Research output per year
Research output per year
Msc., Ph.D. (Physiology)
Grønnegårdsvej 7
1870 Frederiksberg C
Research activity per year
The central part of my research is understanding how small arterioles and arterioles detect a local change in blood pressure, blood flow or oxygen availability and translates it into a change in the diameter of the vessel. This is also called arteriolar tone regulation. In this process K+ channels are extremely important for setting the resting membrane potential of the vascular smooth muscle and endothelial cells of the vascular wall. Voltage-dependent and receptor- or mechano-activated Ca2+ channels are important for providing the Ca2+ influx that is crucial for active constriction of the arterioles. Finally, I am interested in the molecular mechanisms that detect a change in pressure, flow or PO2, and which leads to the downstream activation of signaling mechanisms in the vascular wall and changes in arteriolar tone.
English (fluent), Danish (native), German (basic), French (basic), Spanish (basic), Japanese (beginner)
Education
Present and Previous Employments
Invited Lectures
Teaching (overview)
Lectures, theoretical exercises and practicals of cardiovascular and respiratory physiology, acid/base regulation, and the physiology of the autonomous nervous system. Course responsible for the bachelor course in Advanced Mammalian Biology at the Biology-Biotechnology education.
Review- and assessment committees
Member or chairman of several assessment committees for Ph.D. theses, Research Grant Proposals and employment of university tenure track positions in Denmark and abroad. Reviewer for The Journal of Physiology, American Journal of Physiology (Heart and Circulatory), British Journal of Pharmacology, Journal of Molecular and Cellular Cardiology, Journal of Cerebral Blood Flow and Metabolism, Journal of Neurophysiology, Acta Physiologica (Oxford), Basic & Clinical Pharmacology & Toxicology, Journal of Smooth Muscle Research, and Journal of Comparative Physiology (Part B).
Courses
Certified to teach English Language course, project management courses, research group leadership course, and various scientific courses and workshops.
External Funding
Until now I have attracted approx. DKK 5.3 mio. for my independent research projects from The Danish Medical Research Council as well as from several private foundations
Current Research Methodology
Pressure myography of small arteries, calcium imaging of pressurized small arteries, organoid culture of small arteries under pressure and flow, in vivo and in vitro pharmacological studies, immunofluorescense microscopy, quantitative real-time PCR
Memberships
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Conference abstract in journal › Research
Research output: Contribution to journal › Review › Research
Research output: Contribution to journal › Editorial › Research › peer-review
Research output: Contribution to journal › Review › Research › peer-review
Lars Jørn Jensen (Other)
Activity: Talk or presentation types › Lecture and oral contribution
Lars Jørn Jensen (Participant)
Activity: Participating in an event - types › Organisation of and participation in conference
Kirstine Callø (Participant), Sara Enevoldsen (Participant), Helena Bøgeholm Dehn Magnusson (Participant) & Lars Jørn Jensen (Participant)
Activity: Participating in an event - types › Organisation of and participation in conference
Lars Jørn Jensen (Other)
Activity: Talk or presentation types › Lecture and oral contribution
Lars Jørn Jensen (Other)
Activity: Talk or presentation types › Lecture and oral contribution
Lars Jørn Jensen (Participant)
Activity: Participating in an event - types › Participation in workshop, seminar, course
Lars Jørn Jensen (Participant)
Activity: Participating in an event - types › Organisation of and participation in conference
Lars Jørn Jensen (Participant)
Activity: Participating in an event - types › Participation in workshop, seminar, course