Leif Breum

Research output

Research output per year 1991 1995 2008 2009 2016 2020 2024

• 681 Citations
• 19 Journal article
• 2 Conference abstract in journal
• 1 Comment/debate
• 1 Review

Research output per year

Research output per year

Search results

• 2024

  Exercise in newly diagnosed patients with multiple myeloma: A randomized controlled trial of effects on physical function, physical activity, lean body mass, bone mineral density, pain, and quality of life

  Larsen, R. F., Jarden, M., Minet, L. R., Frølund, U. C., Hermann, A. P., Breum, L., Möller, S. & Abildgaard, N., 2024, In: European Journal of Haematology. 113, 3, p. 298-309 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Downloads (Pure)
• 2023

  Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

  Olsen, M. H., Almdal, T. P., Madsbad, S., Ovesen, C., Gluud, C., Sneppen, S. B., Breum, L., Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, E. R., Røder, M. E., Vestergaard, H., Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  19 Downloads (Pure)
• 2022

  Effects of 18-months metformin versus placebo in combination with three insulin regimens on RNA and DNA oxidation in individuals with type 2 diabetes: A post-hoc analysis of a randomized clinical trial

  Larsen, E. L., Kjær, L. K., Lundby-Christensen, L., Boesgaard, T. W., Breum, L., Gluud, C., Hedetoft, C., Krarup, T., Lund, S. S., Mathiesen, E. R., Perrild, H., Sneppen, S. B., Tarnow, L., Thorsteinsson, B., Vestergaard, H., Poulsen, H. E., Madsbad, S. & Almdal, T. P., 2022, In: Free Radical Biology and Medicine. 178, p. 18-25 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  13 Downloads (Pure)
• 2021

  Effect of metformin and insulin vs. placebo and insulin on whole body composition in overweight patients with type 2 diabetes: a randomized placebo-controlled trial

  Nordklint, A. K., Almdal, T. P., Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, L., Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Perrild, H., Madsbad, S., Mathiesen, E. R., Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., 2021, In: Osteoporosis International. 32, p. 1837–1848

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)
• 2020

  Effect of Metformin vs. Placebo in Combination with Insulin Analogues on Bone Markers P1NP and CTX in Patients with Type 2 Diabetes Mellitus

  Nordklint, A. K., Almdal, T. P., Vestergaard, P., Lundby-Christensen, L., Jørgensen, N. R., Boesgaard, T. W., Breum, L., Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Krarup, T., Madsbad, S., Mathiesen, E. R., Perrild, H., Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., 2020, In: Calcified Tissue International. 107, 2, p. 160-169 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes

  Winckler, K., Thorsteinsson, B., Wiinberg, N., Jensen, A. K., Lundby-Christensen, L., Heitmann, B. L., Lund, S. S., Krarup, T., Jensen, T., Vestergaard, H., Breum, L., Sneppen, S., Boesgaard, T., Madsbad, S., Gluud, C., Vaag, A., Almdal, T. P., Tarnow, L. & The CIMT trial group, Oct 2020, In: Journal of Diabetes and its Complications. 34, 10, 107681.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)
• 2018

  The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial

  Nordklint, A. K., Almdal, T. P., Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, L., Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, S., Mathiesen, E. R., Perrild, H., Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)
• 2016

  Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial

  Lundby-Christensen, L., Vaag, A., Tarnow, L., Almdal, T. P., Lund, S. S., Wetterslev, J., Gluud, C., Boesgaard, T. W., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L. & 6 others, Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B., Carstensen, B. & Madsbad, S., 2016, In: B M J Open. 6, 2, e008377.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  14 Citations (Scopus)

• Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus: the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial

  Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., Lund, S. S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B. & 6 others, Carstensen, B., Madsbad, S., Gluud, C., Wetterslev, J., Vaag, A. & Almdal, T. P., 2016, In: B M J Open. 6, 2, e008376.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  34 Citations (Scopus)

• Search for supersymmetry at root s=13 TeV in final states with jets and two same-sign leptons or three leptons with the ATLAS detector

  Aad, G., Abbott, B., Abdallah, J., Abdinov, O., Abeloos, B., Aben, R., Abolins, M., AbouZeid, O. S., Abramowicz, H., Abreu, H., Breum, L., Abreu, R., Adye, T., Dam, M., Hansen, J. D., Hansen, J. B., Xella, S., Hansen, P. H., Petersen, T. C., Thomsen, L. A. & 7 others, Pingel, A. M., Løvschall-Jensen, A. E., Alonso Diaz, A., Monk, J. W., Pedersen, L. E., Wiglesworth, G. & Galster, G. A. G. K., 7 May 2016, In: European Physical Journal C. 76, 5, 259.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  74 Citations (Scopus)

  142 Downloads (Pure)
• 2013

  Under-reporting of adverse effects of tesofensine

  Astrup, A., Madsbad, S., Breum, L., Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2013, In: Lancet. 382, 9887, p. 127 1 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review
  8 Citations (Scopus)
• 2012

  Bilateral primary adrenal lymphoma presenting with adrenal insufficiency

  Holm, J., Breum, L., Stenfeldt, K. & Friberg Hitz, M., 2012, In: Case Reports in Endocrinology. 2012, p. 638298

  Research output: Contribution to journal › Journal article › Research
• 2009

  Effekt af tesofensine på kropsvægt og kropssammensætning hos svært overvægtige

  Nielsen, A-L. H., Larsen, T. M., Madsbad, S., Breum, L., Jensen, T. J., Kroustrup, J. P. & Astrup, A., 2009, In: Ugeskrift for læger. 171, 41-42, p. 2974-2977 4 p.

  Research output: Contribution to journal › Journal article › Research
  8 Citations (Scopus)

• Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial

  Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M. & 31 others, Snorgaard, O., Tarnow, L., Thorsteinsson, B., Vaag, A., Vestergaard, H., Wetterslev, J., Wiinberg, N., CIMT Trial Group, Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M., Snorgaard, O., Thorsteinsson, B. & Vestergaard, H., 2009, In: Diabetes, Obesity and Metabolism. 11, 4, p. 315-22 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  25 Citations (Scopus)

• The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study

  Astrup, A., Madsbad, S., Breum, L., Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, A. M., 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.

  Research output: Contribution to journal › Conference abstract in journal › Research

• The long-term effect of tesofensine on weight loss: interim results from a one-armed, open-labelled extension study

  Sjödin, A. M., Madsbad, S., Breum, L., Kroustrup, J. P., Raben, A. B., Jensen, J. K. S., Meier, D. & Astrup, A., 2009, In: Obesity. 17, Suppl. 2, p. S107 1 p.

  Research output: Contribution to journal › Conference abstract in journal › Research

  46 Citations (Scopus)
• 2008

  Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

  Astrup, A., Madsbad, S., Breum, L., Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-1913 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  172 Citations (Scopus)

• Initiating or Switching to Biphasic Insulin Aspart 30/70 Therapy in Subjects with Type 2 Diabetes Mellitus. An Observational Study

  Breum, L., Almdal, T., Eiken, P., Lund, P. & Christiansen, E., 2008, In: Review of Diabetic Studies. 5, 3, p. 154-162 8 p.

  Research output: Contribution to journal › Journal article › Research

  6 Citations (Scopus)
• 1996

  Aggression and personality: Association with amino acids and monoamine metabolites

  Møller, S. E., Mortensen, E. L., Breum, L., Alling, C., Larsen, O. G., Bøge-Rasmussen, T., Jensen, C. & Bennicke, K., Mar 1996, In: Psychological Medicine. 26, 2, p. 323-331 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  56 Citations (Scopus)
• 1995

  Collagen metabolism in obesity: the effect of weight loss

  Rasmussen, M. H., Jensen, L. T., Andersen, T., Breum, L. & Hilsted, J., Sep 1995, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 19, 9, p. 659-63 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  27 Citations (Scopus)

• Long-term effects of fluoxetine on glycemic control in obese patients with non-insulin-dependent diabetes mellitus or glucose intolerance: Influence on muscle glycogen synthase and insulin receptor kinase activity

  Breum, L., Bjerre, U., Bak, J. F., Jacobsen, S. & Astrup, A., 1995, In: Metabolism - Clinical and Experimental. 44, 12, p. 1570-1576 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  72 Citations (Scopus)

• Pharmacological and clinical studies of ephedrine and other thermogenic agonists

  Astrup, A., Breum, L. & Toubro, S., 1995, In: Obesity Research. 3, Suppl. 4, p. 537S-540S 4 p.

  Research output: Contribution to journal › Review › Research › peer-review

  62 Citations (Scopus)
• 1991

  Cardiac contractility, central haemodynamics and blood pressure regulation during semistarvation

  Stokholm, K. H., Breum, L. & Astrup, A., 1991, In: Clinical Physiology. 11, 6, p. 513-523 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  30 Citations (Scopus)