Personal profile

CV

  • July 1993: First class Honours Degree from the University of Bath, UK (professional placements at Babraham Institute, Cambridge, UK and Max-Planck Institute, Martinsried, München, Germany).
  • March 1997: PhD obtained at Institute of Food Research, Reading, UK/Birkbeck College, London,
  • April 1997-July 2003: Postdoctoral employment at Centre for Crystallographic Studies, Department of Chemistry, University of Copenhagen (funded by the Danish National Research Foundation, the EU and EMBO).
  • August 2003-February 2018: Associate professor at the Department of Chemistry, University of Copenhagen.
  • 2005-2012: Group leader of Biophysical Chemistry Group, Department of Chemistry, University of Copenhagen(Integrated in the Biophysical and Bioinorganic Chemistry Section in 2012)
  • 2016-2021: Section Leader, Biological Chemistry section
  • From March 2018: Professor at the Department of Chemistry, University of Copenhagen
  • Member of ISBUC Structural Biology (https://isbuc.ku.dk/) and Medicinal Chemistry clusters (https://medchem.ku.dk/)
  • 119 published or accepted peer reviewed articles, reviews and conference proceedings, 13 as first author, 51 as corresponding author. 16 additional publications
  • 7081 Web of Science (WoS) and 10209 Google Scholar (GS) citations, 51 cites/article on WoS, H-I of 35 from WoS and 43 from GS, i10index from GS of 99
  • Author of 186 PDB entries

Primary fields of research

Structure-function relationship in proteins, with recent focus mainly on carbohydrate-active protein, DNA-binding transcription factors and protein engineering/design. X-ray crystallography and more recently small angle scattering are the main techniques used.

Teaching

  • Adjunktpædagogikum obtained in August 2003
  • Teaching in various Protein Chemistry, Crystallography, Biophysical Chemistry, Biological Chemistry and General Chemistry courses at undergraduate and master level
  • Co-organizer and teacher of several editions of the annual PhD Course in Protein Crystallography at the Department of Chemistry, University of Copenhagen. Teacher in 2005 in the PhD Course in Biophysical Chemistry, at the Department of Chemistry, University of Copenhagen. Teacher in several rounds of Graduate School Course in Food Enzymology and Glycobiology, Wageningen/Groningen
  • Current main supervisor of 1 Postdoc, 1 PhD student, 1 guest PhD student, 1 Research assistant , 3 MSc students, 2 BSc students
  • Previously main supervisor of 9 Postdocs, 10 PhD students, 28 M.Sc. students, 14 B.Sc. students, 7 projects outside course scope students, 1 trainee technician, > 5 research assistants, 1 staff scientist. 15 foreign guest students/postdocs at different stages in their studies. Co-supervisor of two additional PhD students.

Current research

Recent grants

  • PI for DFF FTP grant ‘HIPPO: InHIbitors of plant Pathogen’s lytic Polysaccharide mono Oxygenases’ (2025-2030, 6.2 million DKK)
  • PI for DFF FTP grant ‘Prodrug production through enzymatic glycosylation’ (2025-2029, 3.2 million DKK)
  • PI for Novo Nordisk Fonden project grant ‘Time-resolved studies of the Lytic Polysaccharide MonoOxygenase reactions’ (2025-2027, 3 million DKK)
  • HALRIC pilot project ‘Towards time-resolved studies of the Lytic Polysaccharide Monooxygenase reaction’ (2024, ~150K DKK)
  • PI for Radical Innovation Sprint project ‘FRESHEN - Facile Removal of hydrogEn SulpHide by Enzymes’ (2024, ~300K DKK)
  • PI for DFF FNU Grant ‘pH dependent protonation of protein residues (pPP)’ (2023-2027, 2.9 million DKK)
  • PI for Green Transition DFF grant ‘Novel biomass derived compounds as biodegradable plasticisers’ (2023-2026, 2.9 million DKK

Keywords

  • Faculty of Science

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or