Research output per year
Research output per year
Personal profile
CV
Associate Professor at Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen 2010 -
Assistant Professor at the Department of Pharmaceutics and Analytical Chemistry, The Faculty of Pharmaceutical Sciences, University of Copenhagen, 2005 - 2010.
PhD degree from the Danish University of Pharmaceutical Sciences, 2004
Primary fields of research
Analysis of the structure and stability of biomacromolecules in pharmaceutical processes and pharmaceutical formulations.
Formulation and effects from formulation on the stability of proteins.
Regulatry aspects of protein product design and production.
Teaching
BA project in Pharmacy
Master courses at MIND and/or MRA
Thesis supervison of students of pharmacy, MPS, MIND and MRA.
Keywords
- Former Faculty of Pharmaceutical Sciences
- Protein formulation
- Drug delivery
- emulsion/microemulsion
- drug release
- excipients interactions
- Protein characterisation
- FTIR
- fluorescence
- dynamic light scattering
- bovine serum albumin (BSA)
- nanoparticles
- peptide delivery
- pharmaceuticals
- surfactants
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces
Pinholt, C., Kapp, S. J., Bukrinsky, J. T., Hostrup, S., Frokjaer, S., Norde, W. & Jorgensen, L., 2013, In: International Journal of Pharmaceutics. 440, 1, p. 63-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients
Jørgensen, L., Hostrup, S., Møller, E. H. & Grohganz, H., 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230Research output: Contribution to journal › Review › Research
107 Citations (Scopus) -
The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?
Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, L., 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964Research output: Contribution to journal › Journal article › Research › peer-review
94 Citations (Scopus) -
Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines
Jørgensen, L. & Nielsen, H. M., 2009, Wiley. 413 p.Research output: Book/Report › Book › Research › peer-review
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Screening of novel excipients for freeze-dried protein formulations
Holm, T. P., Meng-Lund, H., Rantanen, J., Jorgensen, L. & Grohganz, H., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains
Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jorgensen, L. & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Exploring the chemical space for freeze-drying excipients
Meng-Lund, H., Holm, T. P., Poso, A., Jorgensen, L., Rantanen, J. & Grohganz, H., 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices
Zeeshan, F., Tabbassum, M., Jorgensen, L. & Medlicott, N. J., 2018, In: Applied Spectroscopy. 72, 2, p. 268-279 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus)
Activities
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Protein physical stability in drug delivery systems, and protein absorption to interfaces: Challanges in the delivery of large molecules
Lene Jørgensen (Lecturer)
17 Feb 2010 → 18 Feb 2010Activity: Talk or presentation types › Lecture and oral contribution
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Protein physical stability in drug delivery systems, and protein absorption to interfaces: Challanges in the delivery of large molecules
Lene Jørgensen (Lecturer)
17 Feb 2010 → 18 Feb 2010Activity: Talk or presentation types › Lecture and oral contribution
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Peptider og proteiner- udvikling, fremstilling og formulering: FormuleringPrincipper, pulver, opløsninger, suspensioner tilinjektion. Oral administration, formuleringer tilsubcutan og intramuskulær administration)Produktionsudfordringer (Sterilitet, stabilitet, isotonimm)
Lene Jørgensen (Participant)
3 Apr 2008Activity: Other activity types › Other (prizes, external teaching and other activities) - External teaching and subject coordination
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Hvordan laver man lægemidler?
Lene Jørgensen (Lecturer)
2 Apr 2008Activity: Talk or presentation types › Lecture and oral contribution
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Hvordan laver man lægemidler?
Lene Jørgensen (Lecturer)
7 Feb 2008Activity: Talk or presentation types › Lecture and oral contribution
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Fortællinger om EPO
Lene Jørgensen (Lecturer)
15 Nov 2007Activity: Talk or presentation types › Lecture and oral contribution
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Insulin før nu og i fremtiden
Lene Jørgensen (Lecturer)
26 Jan 2007Activity: Talk or presentation types › Lecture and oral contribution
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Peptider og proteiner- udvikling, fremstilling og formulering: FormuleringPrincipper, pulver, opløsninger, suspensioner tilinjektion. Oral administration, formuleringer tilsubcutan og intramuskulær administration)Produktionsudfordringer (Sterilitet, stabilitet, isotonimm)
Lene Jørgensen (Participant)
25 Jan 2007Activity: Other activity types › Other (prizes, external teaching and other activities) - External teaching and subject coordination