Research output per year
Research output per year
Personal profile
Primary fields of research
My PhD project focuses on using mass spectrometry (MS)- based proteomics technology to understand chronic liver disease, particularly steatohepatitis and liver fibrosis which are the key events on the spectrum of liver disease progression. For this, I'm establishing a cell-type resolved human liver proteome atlas, which will be a publicly available resource for research on both basic liver physiology and pathology. I'm also investigating the proteome changes of both plasma and liver tissue under pathological states.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis
Steigerwald, S., Sinha, A., Fort, K. L., Zeng, W-F., Niu, L., Wichmann, C., Kreutzmann, A., Mourad, D., Aizikov, K., Grinfeld, D., Makarov, A., Mann, M. & Meier, F., 2024, In: Molecular and Cellular Proteomics. 12 p., 100713.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)16 Downloads (Pure) -
Imputation of label-free quantitative mass spectrometry-based proteomics data using self-supervised deep learning
Webel, H., Niu, L., Nielsen, A. B., Locard-Paulet, M., Mann, M., Jensen, L. J. & Rasmussen, S., 2024, In: Nature Communications. 15, 15 p., 5405.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)7 Downloads (Pure) -
Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases
Thiele, M., Villesen, I. F., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Espen, L. V., Keller, M., Israelsen, M., Suvitaival, T., Zawadzki, A. D., Juel, H. B., Brol, M. J., Stinson, S. E., Huang, Y., Silva, M. C. A., Kuhn, M., Anastasiadou, E., Leeming, D. J., Karsdal, M. & 12 others, , 2024, In: Journal of Hepatology. 81, 2, p. 345-359Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile6 Citations (Scopus)5 Downloads (Pure) -
Unbiased Proteomic Exploration Suggests Overexpression of Complement Cascade Proteins in Plasma from Patients with Psoriasis Compared with Healthy Individuals
Kromann, B., Niu, L., Møller, L. B. P., Sølberg, J., Sulek, K., Gyldenløve, M., Dyring-Andersen, B., Skov, L. & Løvendorf, M. B., 2024, In: International Journal of Molecular Sciences. 25, 16, 7 p., 8791.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure) -
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]
Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, , 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile37 Citations (Scopus)90 Downloads (Pure) -
A knowledge graph to interpret clinical proteomics data
Santos, A., Colaço, A. R., Nielsen, A. B., Niu, L., Strauss, M., Geyer, P. E., Coscia, F., Albrechtsen, N. J. W., Mundt, F., Jensen, L. J. & Mann, M., 2022, In: Nature Biotechnology. 40, p. 692–702Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile132 Citations (Scopus)93 Downloads (Pure) -
Dynamic human liver proteome atlas reveals functional insights into disease pathways
Niu, L., Geyer, P. E., Gupta, R., Santos, A., Meier, F., Doll, S., Wewer Albrechtsen, N. J., Klein, S., Ortiz, C., Uschner, F. E., Schierwagen, R., Trebicka, J. & Mann, M., 2022, In: Molecular Systems Biology. 18, 5, 24 p., e10947.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Citations (Scopus)29 Downloads (Pure) -
Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation
Stocks, B., Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, L., Zierath, J. R. & Deshmukh, A. S., 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Citations (Scopus)57 Downloads (Pure)