Research output per year
Research output per year
- 1 - 50 out of 204 results
Search results
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2024
Pharmacogenetic testing of CYP2D6, CYP2C19 and CYP2C9 in Denmark: Agreement between publicly funded genotyping tests and the subsequent phenotype classification
Baltzer Houlind, M., Hansen, L., Iversen, E., Rasmussen, H. B., Larsen, J. B., Jørgensen, S., Dalhoff, K., Damkier, P., Walls, A. B., Vermehren, C., Andersen, T. R. H., Kallemose, T., Christrup, L. & Westergaard, N., 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 5, p. 756-763 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Use of drugs with pharmacogenomics (PGx)-based dosing guidelines in a Danish cohort of persons with chronic kidney disease, both on dialysis and not on dialysis: Perspectives for prescribing optimization
Westergaard, N., Baltzer Houlind, M., Christrup, L. L., Juul-Larsen, H. G., Strandhave, C. & Olesen, A. E., 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 4, p. 531-542Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
2023
The Sixth European Society of Pharmacogenomics and Personalised Therapy Congress
Van Schaik, R. H. N., Manolopoulos, V. G., Daly, A. K., Niemi, M., Zukic, B., Patrinos, G. P., Primorac, D., Swen, J. J., Ingelman-Sundberg, M., Morris, T., Molden, E., Müller, D., Pavlovic, S., Russmann, S., Ansari, M., Henricks, L. M., Van Den Broek, W., Florindi, F., Bozina, N., Akin, D. & 4 others, , 2023, In: Pharmacogenomics. 24, 5, p. 243-246 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
2022
Farmakogenetik kan blive supplement til fremtidens ordinationspraksis
Clausen, E., Koch, N. E., Christrup, L. L., Houlind, M. B. & Nørgaard, L. S., 2022, In: Best Practice Nordic.Research output: Contribution to journal › Journal article › Research
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2021
Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone
Ladebo, L., Abuhelwa, A. Y., Foster, D. J. R., Kroustrup, J. P., Pacyk, G. J., Kongstad, K. T., Drewes, A. M., Christrup, L. L. & Olesen, A. E., 2021, In: Basic and Clinical Pharmacology and Toxicology. 129, 3, p. 232-245Research output: Contribution to journal › Journal article › Research › peer-review
File4 Citations (Scopus) -
Oral absorption of oxycodone in patients with short bowel syndrome
Ladebo, L., Vinter-Jensen, L., Hestvang, J., Mikkelsen, M. S., Rasmussen, H. H., Christrup, L. L., Drewes, A. M. & Olesen, A. E., 2021, In: Scandinavian Journal of Gastroenterology. 56, 9, p. 1023-1029Research output: Contribution to journal › Journal article › Research › peer-review
File1 Citation (Scopus) -
2020
Chronic abdominal pain and persistent opioid use after bariatric surgery
Simoni, A. H., Ladebo, L., Christrup, L. L., Drewes, A. M., Johnsen, S. P. & Olesen, A. E., 2020, In: Scandinavian Journal of Pain. 20, 2, p. 239-251Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile17 Citations (Scopus)74 Downloads (Pure) -
Opioider til kroniske nonmaligne smerter
Translated title of the contribution :Opioids for chronic non-malignant pain Research output: Contribution to journal › Review › Research › peer-review
Open Access1 Citation (Scopus) -
Population pharmacokinetic-pharmacodynamic modelling of liquid and controlled-release formulations of oxycodone in healthy volunteers
Ladebo, L., Foster, D. J. R., Abuhelwa, A. Y., Upton, R. N., Kongstad, K. T., Drewes, A. M., Christrup, L. L. & Olesen, A. E., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 3, p. 263-276Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
2019
Differences in Kidney Function Estimates Based on Creatinine and/or Cystatin C in Non-Traumatic Amputation Patients and Their Impact on Drug Prescribing
Aakjaer, M., Houlind, M. B., Treldal, C., Ankarfeldt, M. Z., Jensen, P. S., Andersen, O., Iversen, E., Christrup, L. L. & Petersen, J., 2019, In: Journal of Clinical Medicine. 8, 1, 14 p., 89.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)229 Downloads (Pure) -
2018
Association Between Genetic Polymorphisms and Pain Sensitivity in Patients with Hip Osteoarthritis
Olesen, A. E., Nielsen, L. M., Feddersen, S., Erlenwein, J., Petzke, F., Przemeck, M., Christrup, L. L. & Drewes, A. M., 2018, In: Pain Practice. 18, 5, 587 p.Research output: Contribution to journal › Journal article › Research › peer-review
24 Citations (Scopus) -
Creatinine-Based Renal Function Estimates and Dosage of Postoperative Pain Management for Elderly Acute Hip Fracture Patients
Houlind, M. B., Petersen, K. K., Palm, H., Jorgensen, L. M., Aakjaer, M., Christrup, L. L., Petersen, J., Andersen, O. & Treldal, C., 2018, In: Pharmaceuticals. 11, 3, 14 p., 88.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)318 Downloads (Pure) -
GENOMIC AIDED PHARMACOTHERAPY (GAP): A PILOT STUDY IN PATIENTS SUFFERING FROM CHRONIC NON-CANCER PAIN
Houlind, M. B., Treldal, C., Vagn-Hansen, L., Hansen, R. W. & Christrup, L. L., May 2018, p. 10-10.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Open AccessFile769 Downloads (Pure) -
Healthcare professionals’ agreement on clinical relevance of drug-related problems among elderly patients
Bech, C. F., Frederiksen, T., Villesen, C. T., Højsted, J., Nielsen, P. R., Kjeldsen, L. J., Nørgaard, L. S. & Christrup, L. L., 2018, In: International Journal of Clinical Pharmacy. 40, 1, p. 119-125Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Offset Analgesia and The Impact of Treatment with Oxycodone and Venlafaxine: A Placebo-Controlled, Randomized Trial in Healthy Volunteers
Olesen, A. E., Nissen, T. D., Nilsson, M., Lelic, D., Brock, C., Christrup, L. L. & Drewes, A. M., 2018, In: Basic and Clinical Pharmacology and Toxicology. 123, 6, p. 727-731Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Recreational drug use at a major music festival: trend analysis of anonymised pooled urine
Hoegberg, L., Christiansen, C., Søe, J. L., Telving, R., Andreasen, M. F., Stærk, D., Christrup, L. L. & Kongstad, K. T., 2018, In: Clinical Toxicology. 56, p. 245-255 1360496.Research output: Contribution to journal › Journal article › Research › peer-review
16 Citations (Scopus) -
2017
Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches
Juul, R. V., Nyberg, J., Kreilgaard, M., Christrup, L. L., Simonsson, U. S. H. & Lund, T. M., Aug 2017, In: Journal of Pharmacokinetics and Pharmacodynamics. 44, 4, p. 325-333 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Cortical and spinal assessment - a comparative study using encephalography and the nociceptive withdrawal reflex
Fischer, I. W., Gram, M., Hansen, T. M., Brokjaer, A., Graversen, C., Malver, L. P., Mørch, C. D., Christrup, L. L., Drewes, A. M. & Olesen, A. E., Mar 2017, In: Journal of Pharmacological and Toxicological Methods. 84, p. 37-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
European Pain Federation position paper on appropriate opioid use in chronic pain management
O'Brien, T., Christrup, L. L., Drewes, A. M., Fallon, M. T., Kress, H. G., McQuay, H. J., Mikus, G., Morlion, B. J., Perez-Cajaraville, J., Pogatzki-Zahn, E., Varrassi, G. & Wells, J. C. D., Jan 2017, In: European Journal of Pain. 21, 1, p. 3-19 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile167 Citations (Scopus)154 Downloads (Pure) -
Genetic Influences of OPRM1, OPRD1 and COMT on Morphine Analgesia in a Multi-Modal, Multi-Tissue Human Experimental Pain Model
Nielsen, L. M., Christrup, L. L., Sato, H., Drewes, A. M. & Olesen, A. E., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology Online. 121, 1, p. 6-12Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics
Nielsen, L. M., Sverrisdóttir, E., Stage, T. B., Feddersen, S., Brøsen, K., Christrup, L. L., Drewes, A. M. & Olesen, A. E., 1 Mar 2017, In: European Journal of Pharmaceutical Sciences. 99, p. 337-342 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
24 Citations (Scopus) -
Objective methods for the assessment of the spinal and supraspinal effects of opioids
Fischer, I. W., Hansen, T. M., Lelic, D., Brokjaer, A., Frøkjær, J., Christrup, L. L. & Olesen, A. E., Jan 2017, In: Scandinavian Journal of Pain. 14, p. 15-24 10 p.Research output: Contribution to journal › Review › Research › peer-review
13 Citations (Scopus) -
2016
A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain
Knøsgaard, K., Juul, R. V., Olesen, A. E., Pedersen, K. V., Kreilgaard, M., Christrup, L. L., Osther, P. J. S., Drewes, A. M. & Lund, T. M., Jun 2016.Research output: Contribution to conference › Poster › Research
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A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain
Juul, R. V., Knøsgaard, K. R., Olesen, A. E., Pedersen, K. V., Kreilgaard, M., Christrup, L. L., Osther, P. J., Drewes, A. M. & Lund, T. M., Jul 2016, In: A A P S Journal. 18, 4, p. 1013-1022 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
A pharmacokinetic-pharmacodynamic model of morphine exposure and subsequent morphine consumption in postoperative pain
Juul, R. V., Nyberg, J., Lund, T. M., Rasmussen, S., Kreilgaard, M., Christrup, L. L. & Simonsson, U. S. H., 2016, In: Pharmaceutical Research. 33, 5, p. 1093–1103 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Association between Gene Polymorphisms and Pain Sensitivity Assessed in a Multi-Modal Multi-Tissue Human Experimental Model - An Explorative Study
Nielsen, L. M., Olesen, A. E., Sato, H., Christrup, L. L. & Drewes, A. M., Oct 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 4, p. 360-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Definition, diagnosis and treatment strategies for opioid-induced bowel dysfunction - Recommendations of the Nordic Working Group
Drewes, A. M., Munkholm, P., Simrén, M., Breivik, H., Kongsgaard, U. E., Hatlebakk, J. G., Agreus, L., Friedrichsen, M. & Christrup, L. L., 2016, In: Scandinavian Journal of Pain. 11, p. 111-122 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access76 Citations (Scopus) -
Pharmacokinetic Metamodel of Morphine and Morphine-6-Glucuronide in Neonates and Adults
Sverrisdóttir, E., Foster, D. J. R., Olesen, A. E., Lund, T. M., Drewes, A. M., Christrup, L. L., Kreilgaard, M. & Upton, R. N., Jun 2016.Research output: Contribution to conference › Poster › Research
Open AccessFile219 Downloads (Pure) -
Short-term oxycodone treatment does not affect electrogenic ion transport in isolated mucosa from the human rectosigmoid colon
Nilsson, M., Brock, C., Poulsen, J. L., Bindslev, N., Hansen, M. B., Louring Christrup, L. & Drewes, A. M., 2016, In: Scandinavian Journal of Gastroenterology. 51, 5, p. 538-47 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
2015
A cortical source localization analysis of resting EEG data after remifentanil infusion
Khodayari-Rostamabad, A., Graversen, C., Malver, L. P., Kurita, G. P., Christrup, L. L., Sjøgren, P. & Drewes, A. M., 2015, In: Clinical Neurophysiology. 126, 5, p. 898-905Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Altered Frequency Distribution in the Electroencephalogram is Correlated to the Analgesic Effect of Remifentanil
Graversen, C., Malver, L. P., Kurita, G. P., Staahl, C., Christrup, L. L., Sjøgren, P. & Drewes, A. M., May 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 5, p. 414-422 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain
Sverrisdóttir, E., Lund, T. M., Olesen, A. E., Drewes, A. M., Christrup, L. L. & Kreilgaard, M., 7 Apr 2015, In: European Journal of Pharmaceutical Sciences. 74, p. 45–62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
106 Citations (Scopus) -
Association Between Human Pain-Related Genotypes and Variability in Opioid Analgesia: An Updated Review
Nielsen, L. M., Olesen, A. E., Branford, R., Christrup, L. L., Sato, H. & Drewes, A. M., 2015, In: Pain Practice. 15, 6, p. 580–594 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
58 Citations (Scopus) -
Disruption of Cortical Connectivity during Remifentanil Administration Is Associated with Cognitive Impairment but Not with Analgesia
Khodayari-Rostamabad, A., Olesen, S. S., Graversen, C., Malver, L. P., Kurita, G. P., Sjøgren, P., Christrup, L. L. & Drewes, A. M., 2015, In: Anesthesiology. 122, p. 140-49 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
16 Citations (Scopus) -
Does mutual compensation of the cognitive effects induced by pain and opioids exist? An experimental study
Kurita, G. P., Malver, L. P., Andresen, T., Polianskis, R., Drewes, A. M., Christrup, L. L., Højsted, J. & Sjøgren, P., 2015, In: Psychopharmacology. 232, 8, p. 1373-1381 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
Exploratory survey study of long-term users of nicotine replacement therapy in Danish consumers
Borup, G., Lyngby Mikkelsen, K., Tønnesen, P. & Christrup, L. L., 19 Jan 2015, In: Harm Reduction Journal. 12, 2, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access4 Citations (Scopus) -
Exploring the relationship between analgesic event rate and pain intensity in kidney stone surgery: A Repeated Time to Event Pilot Study
Juul, R. V., Pedersen, K. V., Christrup, L. L., Olesen, A. E., Drewes, A., Osther, P. J. S. & Lund, T. M., Jun 2015.Research output: Contribution to conference › Poster › Research › peer-review
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Management of non-malignant chronic pain conditions with opioids; cross-sectional challenges
Villesen, C. T., Højsted, J., Nørgaard, L. S., Kjeldsen, L. J., Nielsen, P. R. & Christrup, L. L., 2015, In: International Journal of Clinical Pharmacy. 37, 1, p. 255 1 p., HP-CE022.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Modelling concentration-analgesia relationships for morphine to evaluate experimental pain models
Sverrisdóttir, E., Foster, D. J. R., Upton, R. N., Olesen, A. E., Lund, T. M., Gabel-Jensen, C., Drewes, A. M., Christrup, L. L. & Kreilgaard, M., 23 Jan 2015, In: European Journal of Pharmaceutical Sciences. 66, p. 50-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
16 Citations (Scopus) -
Modelling drug-drug interactions between morphine and methylnaltrexone
Sverrisdóttir, E., Kreilgaard, M., Brokjær, A., Miltersen, K. K., Olesen, A. E., Christrup, L. L. & Drewes, A., 2015.Research output: Contribution to conference › Poster › Research
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Objective markers of the analgesic response to morphine in experimental pain research
Brokjær, A., Olesen, A. E., Kreilgaard, M., Graversen, C., Gram, M., Christrup, L. L., Dahan, A. & Drewes, A. M., 7 Feb 2015, In: Journal of Pharmacological and Toxicological Methods. 73, p. 7-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
7 Citations (Scopus) -
PS-109 Barriers and facilitators to implementing drug changes caused by drug tenders and shortages
Rishøj, R. M., Christrup, L. L. & Clemmensen, M. H., 2015, In: European Journal of Hospital Pharmacy - Science and Practice. 22, p. A185-A186 2 p.Research output: Contribution to journal › Journal article › Research
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Renal function and symptoms/adverse effects in opioid-treated patients with cancer
Kurita, G. P., Lundström, S., Sjøgren, P., Ekholm, O., Christrup, L., Davies, A., Kaasa, S., Klepstad, P. & Dale, O., Sep 2015, In: Acta Anaesthesiologica Scandinavica. 59, 8, p. 1049-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
23 Citations (Scopus) -
Repeated Time-to-event Analysis of Consecutive Analgesic Events in Postoperative Pain
Juul, R. V., Rasmussen, S., Kreilgaard, M., Christrup, L. L., Simonsson, U. S. H. & Lund, T. M., 2015, In: Anesthesiology. 123, 12, p. 1411-1419 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
28 Citations (Scopus) -
Symptoms and side effects in chronic non-cancer pain patients: clinical implications and development of new assessment tools
Olsen, T. S., Jonsson, T., Højsted, J., Sjøgren, P. & Christrup, L., Sep 2015, In: Acta Anaesthesiologica Scandinavica. 59, 8, p. 1060-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of morphine and methylnaltrexone on gastrointestinal pain in healthy male participants
Brokjaer, A., Olesen, A. E., Christrup, L. L., Dahan, A. & Drewes, A. M., May 2015, In: Neurogastroenterology and Motility. 27, 5, p. 693-704 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
2014
Altered cortical causality after remifentanil administration in healthy volunteers: A novel approach for pharmaco-EEG
Khodayari-Rostamabad, A., Graversen, C., Olesen, S. S., Malver, L. P., Kurita, G. P., Sjogren, P., Christrup, L. L. & Drewes, A. M., Aug 2014, In: I E E E Engineering in Medicine and Biology Society. Conference Proceedings. 2014, p. 4290-4293 4 p.Research output: Contribution to journal › Conference article › Research › peer-review
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Barriers to cancer pain management in danish and lithuanian patients treated in pain and palliative care units
Jacobsen, R., Samsanaviciene, J., Liubarskiene, Z., Sjøgren, P., Møldrup, C., Christrup, L. L., Sciupokas, A. & Hansen, O. B., Mar 2014, In: Pain management nursing : official journal of the American Society of Pain Management Nurses. 15, 1, p. 51-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Being a long-term user of nicotine replacement therapy: Interpretative phenomenological analysis of former smokers’ experience of continued nicotine dependence
Borup, G., Nørgaard, L. S., Tønnesen, P. & Christrup, L. L., 18 Sep 2014.Research output: Contribution to conference › Poster › Research
File866 Downloads (Pure) -
Comparison of 5 health care professionals’ratings of the clinical significance of drug related problems
Villesen, C., Hojsted, J., Kjeldsen, L. J., Nørgaard, L. S., Nielsen, P. R. & Christrup, L. L., Mar 2014, In: European Journal of Hospital Pharmacy - Science and Practice. 21, p. A61-A62Research output: Contribution to journal › Conference abstract in journal › Research › peer-review