Personal profile
Short presentation
Glycosaminoglycans are clinically used heterogeneous polysaccharides drugs derived from animal sources. Miller R. Group works on applying genetic engineering of the GAG biosynthetic pathway in cells to generate materials that can be used to systematically develop instrumentation, such as mass spectrometry and single-molecule methods. Characterisation of the glycosaminoglycan sulfation code with its function paves the way for the development of sustainable lab-derived homogenous glycosaminoglycan drugs.
Education/Academic qualification
Human Physiology, MSc., Involvement of RhoA in regulating skeletal muscle mass and insulin-stimulated muscle glucose uptake, The August Krogh Section for Molecular Physiology
1 Sept 2019 → 10 Jan 2022
Award Date: 10 Jan 2022
Sport Sciences & Health, BSc., GDF-11 declines with age but cannot be used as a biomarker for sarcopenia, University of Southern Denmark (SDU)
1 Sept 2016 → 12 Jun 2019
Award Date: 12 Jun 2019
Collaborations and top research areas from the last five years
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Structural basis for human chondroitin sulfate chain polymerization
Dutta, P., Cordeiro, R. L., Friedel-Arboleas, M., Bourgeais, M., Vallet, S. D., Weber, M., Molinas, M., Shu, H., Grønset, M. N. N., Miller, R. L., Boeri Erba, E. & Wild, R., 2025, In: Nature Communications. 16, 1, 15 p., 11663.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Downloads (Pure) -
Mammalian cell-based production of glycans, glycopeptides and glycomodules
Jaroentomeechai, T., Karlsson, R., Goerdeler, F., Teoh, F. K. Y., Grønset, M. N., de Wit, D., Chen, Y.-H., Furukawa, S., Psomiadou, V., Hurtado-Guerrero, R., Vidal-Calvo, E. E., Salanti, A., Boltje, T. J., van den Bos, L. J., Wunder, C., Johannes, L., Schjoldager, K. T., Joshi, H. J., Miller, R. L. & Clausen, H. & 2 others, , 2024, In: Nature Communications. 15, 1, 16 p., 9668.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)25 Downloads (Pure) -
Methods and Materials for Studying Proteoglycans and Glycosaminoglycans
Karlsson, R., Grønset, M. N., Chuang, C., Hippensteel, J. A. & Miller, R. L., 2024, New Developments in Mass Spectrometry. Struwe, W. B. (ed.). Royal Society of Chemistry, Vol. 15. p. 29-60 32 p. (New Developments in Mass Spectrometry, Vol. 15).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Remodeling of skeletal muscle myosin metabolic states in hibernating mammals
Lewis, C. T. A., Melhedegaard, E. G., Ognjanovic, M. M., Olsen, M. S., Laitila, J., Seaborne, R. A. E., Gronset, M., Zhang, C., Iwamoto, H., Hessel, A. L., Kuehn, M. N., Merino, C., Amigo, N., Frobert, O., Giroud, S., Staples, J. F., Goropashnaya, A. V., Fedorov, V. B., Barnes, B. & Toien, O. & 3 others, , 2024, In: eLife. 13, 26 p., RP94616.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile38 Downloads (Pure)