Marco van de Weert

Research output

Research output per year 1996 2002 2005 2007 2008 2009 2011 2012 2013 2014 2015 2016 2024

• 5924 Citations
• 90 Journal article
• 9 Book chapter
• 6 Review
• 3 Comment/debate
• 8 More
  • 2 Conference abstract for conference
  • 2 Editorial
  • 1 Preface/postscript
  • 1 Conference abstract in journal
  • 1 Letter
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2024

  Amino acids as stabilizers for lysozyme during the spray-drying process and storage

  Zhang, C., Jørgensen, F. S., van de Weert, M., Bjerregaard, S., Rantanen, J. & Yang, M., 2024, In: International Journal of Pharmaceutics. 659, 124217.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  9 Downloads (Pure)

• Leucine as a Moisture-Protective Excipient in Spray-Dried Protein/Trehalose Formulation

  Zhang, C., van de Weert, M., Bjerregaard, S., Rantanen, J. & Yang, M., 2024, In: Journal of Pharmaceutical Sciences. 113, 9, p. 2764-2774

  Research output: Contribution to journal › Journal article › Research › peer-review

• Ligand binding to proteins: When flawed fluorescence quenching methodology and interpretation become the new norm

  van de Weert, M. & Schönbeck, C., 2024, In: European Journal of Pharmaceutical Sciences. 203, 6 p., 106930.

  Research output: Contribution to journal › Letter › Research › peer-review

  Open Access

  File
• 2023

  Corrigendum to "Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites" [J. Colloid Interface Sci. 606(Part 2) (2022) 1928-1939]

  Zhou, X., Galparsoro, D. F., Madsen, A. Ø., Vetri, V., van de Weert, M., Nielsen, H. M. & Foderà, V., 2023, In: Journal of Colloid and Interface Science. 640, p. 917

  Research output: Contribution to journal › Journal article › Communication

  File

• Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy

  Zhou, X., Sinkjær, A. W., Zhang, M., Pinholt, H. D., Nielsen, H. M., Hatzakis, N. S., van de Weert, M. & Foderà, V., 2023, In: The Journal of Physical Chemistry Letters. 14, 4, p. 912-919

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  17 Downloads (Pure)
• 2022

  Interchangeability of biosimilars: A study of expert views and visions regarding the science and substitution

  Druedahl, L. C., Kälvemark Sporrong, S., Minssen, T., Hoogland, H., De Bruin, M. L. M., van de Weert, M. & Almarsdóttir, A. B., 2022, In: PLOS One. 17, 1, p. 1-13 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

  59 Downloads (Pure)

• Ion-Mediated Morphological Diversity in Protein Amyloid Systems

  Chaaban, H., Vallooran, J. J., Van De Weert, M. & Foderà, V., 2022, In: Journal of Physical Chemistry Letters. 13, 16, p. 3586-3593

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)

  22 Downloads (Pure)

• Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites

  Zhou, X., Fennema Galparsoro, D., Østergaard Madsen, A., Vetri, V., van de Weert, M., Mørck Nielsen, H. & Foderà, V., 2022, In: Journal of Colloid and Interface Science. 606, Pt 2, p. 1928-1939

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  16 Downloads (Pure)
• 2021

  Evolving biosimilar clinical requirements: A qualitative interview study with industry experts and European national medicines agency regulators

  Druedahl, L. C., Kälvemark Sporrong, S., van de Weert, M., De Bruin, M. L. M., Hoogland, H., Minssen, T. & Almarsdóttir, A. B., 2021, In: BioDrugs. 35, p. 351-361

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Polysorbate 80 Controls Morphology, Structure and Stability of Human Insulin Amyloid-Like Spherulites

  Zhou, X., Galparsoro, D. F., Madsen, A. Ø., Vetri, V., Weert, M. V. D., Nielsen, H. M. & Foderà, V., 10 Aug 2021, bioRxiv, 52 p.

  Research output: Working paper › Preprint › Research

  Open Access

  File
  29 Downloads (Pure)
• 2020

  A qualitative study of biosimilar manufacturer and regulator perceptions on intellectual property and abbreviated approval pathways

  Druedahl, L. C., Almarsdóttir, A. B., Kälvemark Sporrong, S., De Bruin, M. L., Hoogland, H., Minssen, T., van de Weert, M., Kesselheim, A. S. & Sarpatwari, A., 2020, In: Nature Biotechnology. 38, 11, p. 1253-1256 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  12 Citations (Scopus)

• Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

  Huang, J., Jacobsen, J., Larsen, S. W., Genina, N., van de Weert, M., Müllertz, A., Nielsen, H. M. & Mu, H., 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)
• 2019

  MEDICINES AUTHORITY REGULATOR AND INDUSTRY PERCEPTIONS OF BIOSIMILAR INTERCHANGEABILITY

  Druedahl, L. C., De Bruin, M. L., Hoogland, H., Minssen, T., van de Weert, M., Sporrong, S. K. & Almarsdottir, A. B., Dec 2019, p. E45-E46.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  Open Access

  File
  306 Downloads (Pure)

• Medicines authority regulators and industry perspectives on the European regulation of biosimilars

  Druedahl, L. C., De Bruin, M. L. M., van de Weert, M., Minssen, T., Hoogland, H. & Almarsdóttir, A. B., 2019.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• The dangers of citing papers you did not read or understand

  van de Weert, M. & Stella, L., 15 Jun 2019, In: Journal of Molecular Structure: THEOCHEM. 1186, p. 102-103 2 p.

  Research output: Contribution to journal › Journal article › Communication
  7 Citations (Scopus)
• 2018

  Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

  Wu, C., van de Weert, M., Baldursdottir, S. G., Yang, M. & Mu, H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin

  Høgstedt, U. B., Østergaard, J., Weiss, T., Sjögren, H. & van de Weert, M., Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

  von Halling Laier, C., Gibson, B., van de Weert, M., Boyd, B. J., Rades, T., Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  34 Citations (Scopus)
• 2017

  Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme

  Meng-Lund, H., Friis, N., van de Weert, M., Rantanen, J., Poso, A., Grohganz, H. & Jorgensen, L., 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  10 Citations (Scopus)

• Investigation of factors affecting the stability of lysozyme spray dried from ethanol-water solutions

  Ji, S., Thulstrup, P. W., Mu, H., Hansen, S. H., van de Weert, M., Rantanen, J. & Yang, M., 2017, In: International Journal of Pharmaceutics. 534, 1-2, p. 263-271 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  10 Citations (Scopus)

• Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity

  Lobbens, E. S. B., Vissing, K. J., Jorgensen, L., van de Weert, M. & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  16 Citations (Scopus)
• 2016

  Effect of ethanol as a co-solvent on the aerosol performance and stability of spray-dried lysozyme

  Ji, S., Thulstrup, P. W., Mu, H., Hansen, S. H., van de Weert, M., Rantanen, J. & Yang, M., 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 175-182 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• Effect of the Freezing Step in the Stability and Bioactivity of Protein-Loaded PLGA Nanoparticles Upon Lyophilization

  Fonte, P., Andrade, F., Azevedo, C., Pinto, J., Seabra, V., van de Weert, M., Reis, S. & Sarmento, B., 2016, In: Pharmaceutical Research. 33, 11, p. 2777–2793

  Research output: Contribution to journal › Journal article › Research › peer-review
  35 Citations (Scopus)

• Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

  Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, H., Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, H. M., Jensen, K. J., Berthelsen, J., Sundström, M. & van de Weert, M., 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  13 Citations (Scopus)

• Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin

  Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, L. & van de Weert, M., 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)

• Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

  Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, B., Jäger, A. K., Jørgensen, L., Uversky, V. & van de Weert, M., 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)

• On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra

  Bortolotti, A., Wong, Y. H., Korsholm, S. S., Bahring, N. H. B., Bobone, S., Tayyab, S., Van De Weert, M. & Stella, L., 2016, In: RSC Advances. 6, 114, p. 112870-112876 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  127 Citations (Scopus)

  465 Downloads (Pure)

• Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

  Esmail Nazari, Z., van de Weert, M., Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, K. D., 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Rhamnogalacturonan-I based microcapsules for targeted drug release

  Svagan, A. J., Kusic, A., De Gobba, C., Larsen, F. H., Sassene, P., Zhou, Q., Van De Weert, M., Mullertz, A., Jørgensen, B. & Ulvskov, P., 2016, In: P L o S One. 11, 12, 13 p., e0168050.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  18 Citations (Scopus)

  348 Downloads (Pure)

• Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions

  Høgstedt, U. B., Schwach, G., van de Weert, M. & Østergaard, J., 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  12 Citations (Scopus)

• The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

  Lobbens, E. S., Foderà, V., Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, L. & van de Weert, M., 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  7 Citations (Scopus)
• 2015

  Co-encapsulation of lyoprotectants improves the stability of protein-loaded PLGA nanoparticles upon lyophilization

  Fonte, P., Araújo, F., Seabra, V., Reis, S., van de Weert, M. & Sarmento, B., 30 Dec 2015, In: International Journal of Pharmaceutics. 496, 2, p. 850-62 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  45 Citations (Scopus)

• Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

  Kapp, S. J., Larsson, I., van de Weert, M., Cardenas Gomez, M. & Jorgensen, L., 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  42 Citations (Scopus)

• Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

  Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, M., Andersen, P., Follmann, F. & Foged, C., 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  82 Citations (Scopus)

• Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

  Kapp, S. J., Larsson, I., Van De Weert, M., Ćardenas, M. & Jorgensen, L., 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.

  Research output: Contribution to journal › Comment/debate › Research
  1 Citation (Scopus)

• Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein

  Klukkert, M., Van De Weert, M., Fanø, M., Rades, T. & Leopold, C. S., 2015, In: Journal of Pharmaceutical Sciences. 104, 12, p. 4314–4321 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)

• Preferential interactions and the effect of protein PEGylation

  Holm, L. S., Thulstrup, P. W., Kasimova, M. R. & van de Weert, M., 2015, In: PLOS ONE. 10, 7, 18 p., e0133584.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  13 Citations (Scopus)

  535 Downloads (Pure)
• 2014

  A reassessment of synchronous fluorescence in the separation of Trp and Tyr contributions in protein emission and in the determination of conformational changes

  Bobone, S., van de Weert, M. & Stella, L., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 68-76 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  100 Citations (Scopus)

• Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability

  Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, M. & Jorgensen, L., 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  66 Citations (Scopus)

• Fluorescence spectroscopy and binding: Getting it right

  Stella, L., van de Weert, M., Burrows, H. D. & Fausto, R., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 1-3 3 p.

  Research output: Contribution to journal › Editorial › Research
  7 Citations (Scopus)

• Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin

  Weisbjerg, P. L. G., Caspersen, M. B., Cook, K. & van de Weert, M., 1 Dec 2014, In: Journal of Pharmaceutical Sciences. 104, 2, p. 548-556 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass

  Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, M., Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  57 Citations (Scopus)

• The Effect of Protein PEGylation on Physical Stability in Liquid Formulation

  Holm, L. S., Mcumber, A., Rasmussen, J. E., Obiols-Rabasa, M., Thulstrup, P. W., Kasimova, M. R., Randolph, T. W. & van de Weert, M., 21 Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 10, p. 3043-3054 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  19 Citations (Scopus)
• 2013

  Characterization of Therapeutic Peptides and Proteins

  van de Weert, M. & Arvinte, T., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 49-78

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

• Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy

  Maltesen, M. J., van de Weert, M. & Grohganz, H., 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review

• Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations

  Trnka, H., Wu, J-X., van de Weert, M., Grohganz, H. & Rantanen, J., Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  20 Citations (Scopus)

• Physical Instability of Peptides and Proteins

  van de Weert, M. & Randolph, T. W., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 107-130

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

• Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30)

  Jensen, M. H., Wahlund, P-O., Toft, K. N., Jacobsen, J. K., Steensgaard, D. B., van de Weert, M., Havelund, S. & Vestergaard, B., 15 Jan 2013, In: Biochemistry. 52, 2, p. 282-94 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• The challenges in and importance of analysing protein structure and physical stability in complex formulations

  Jorgensen, L., Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, M., 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.

  Research output: Contribution to journal › Review › Research › peer-review

• Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements

  Neergaard, M. S., Kalonia, D. S., Parshad, H., Nielsen, A., Møller, E. H., van de Weert, M. & Nielsen, A. D., 26 Apr 2013, In: European Journal of Pharmaceutical Sciences. 49, 3, p. 400-410 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  113 Citations (Scopus)