Research output per year
Research output per year
Search results
-
2024
A mutational atlas for Parkin proteostasis
Clausen, L., Voutsinos, V., Cagiada, M., Johansson, K. E., Grønbæk-Thygesen, M., Nariya, S., Powell, R. L., Have, M. K. N., Oestergaard, V. H., Stein, A., Fowler, D. M., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2024, In: Nature Communications. 15, 1, 17 p., 1541.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)18 Downloads (Pure) -
Cellular and molecular mechanisms of aspartoacylase and its role in Canavan disease
Grønbæk-Thygesen, M. & Hartmann-Petersen, R., 2024, In: Cell and Bioscience. 14, 1, 33 p., 45.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile8 Downloads (Pure) -
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
Grønbæk-Thygesen, M., Voutsinos, V., Johansson, K. E., Schulze, T. K., Cagiada, M., Pedersen, L., Clausen, L., Nariya, S., Powell, R. L., Stein, A., Fowler, D. M., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2024, In: Nature Communications. 15, 1, 18 p., 4026.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
2023
Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components
Kampmeyer, C., Grønbæk-Thygesen, M., Oelerich, N., Tatham, M. H., Cagiada, M., Lindorff-Larsen, K., Boomsma, W., Hofmann, K. & Hartmann-Petersen, R., 2023, In: Cellular and Molecular Life Sciences. 80, 6, 18 p., 143.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)15 Downloads (Pure) -
The moonlighting of RAD23 in DNA repair and protein degradation
Grønbæk-Thygesen, M., Kampmeyer, C., Hofmann, K. & Hartmann-Petersen, R., 2023, In: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1866, 2, 16 p., 194925.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile3 Citations (Scopus)16 Downloads (Pure) -
2022
Studies on how protein missense mutations affect protein stability and degradation
Grønbæk-Thygesen, M., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 203 p.Research output: Book/Report › Ph.D. thesis › Research
-
2021
Mapping the degradation pathway of a disease-linked aspartoacylase variant
Gersing, S. K., Wang, Y., Grønbæk-Thygesen, M., Kampmeyer, C., Clausen, L., Willemoës, M., Andréasson, C., Stein, A., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)31 Downloads (Pure) -
2020
Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation
Clausen, L., Stein, A., Grønbæk-Thygesen, M., Nygaard, L., Søltoft, C. L., Nielsen, S. V., Lisby, M., Ravid, T., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2020, In: PLOS Genetics. 16, 11, 28 p., e1009187.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Citations (Scopus)55 Downloads (Pure)