Mette Andersen Lepola

Research output

Research output per year 2007 2023 2024 2024

• 1074 Citations
• 43 Journal article
• 5 Review

Research output per year

Research output per year

Search results

• 2024

  Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans

  Lin, L., Andersen, M. K., Stæger, F. F., Li, Z., Hanghøj, K., Linneberg, A., Grarup, N., Jørgensen, M. E., Hansen, T., Moltke, I. & Albrechtsen, A., 2024, In: Genome Medicine. 16, 14 p., 71.

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• Characterization of the gut bacterial and viral microbiota in latent autoimmune diabetes in adults

  Poulsen, C. S., Hesse, D., Fernandes, G. R., Hansen, T. H., Kern, T., Linneberg, A., Van Espen, L., Jørgensen, T., Nielsen, T., Alibegovic, A. C., Matthijnssens, J., Pedersen, O., Vestergaard, H., Hansen, T. & Andersen, M. K., 2024, In: Scientific Reports. 14, 1, 11 p., 8315.

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• Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

  Takele, W. W., Vesco, K. K., Josefson, J. L., Redman, L. M., Hannah, W., Bonham, M. P., Chen, M., Chivers, S. C., Fawcett, A. J., Grieger, J. A., Habibi, N., Leung, G. K. W., Liu, K., Mekonnen, E. G., Pathirana, M., Quinteros, A., Taylor, R., Ukke, G. G., Zhou, S. J., Franks, P. W. & 31 others, Rich, S. S., Wagner, R., Vilsbøll, T., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M., Redondo, M. J., Pratley, R. E., Pop-Busui, R., Pollin, T. I., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Murphy, R., Loos, R. J. F., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 15 p., 75.

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  4 Citations (Scopus)

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• Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation

  Frederiksen, T. C., Christiansen, M. K., Benjamin, E. J., Overvad, K., Olsen, A., Andersen, M. K., Hansen, T., Grarup, N., Jensen, H. K. & Dahm, C. C., 2024, In: Heart. 110, p. :644–649

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• Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

  ADA/EASD PMDI, Merino, J., Thuesen, A. C. B., Andersen, M. K., Clemmensen, C., Hansen, T., Nakabuye, M., Loos, R. J. F., Guasch-Ferré, M. & Vilsbøll, T., 2024, In: Communications Medicine. 4, 1, 8 p., 66.

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  5 Citations (Scopus)

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• Low birthweight in patients with type 2 diabetes is associated with elevated risk of cardiovascular events and mortality

  Hansen, A. L., Brøns, C., Engelhard, L. M., Andersen, M. K., Hansen, T., Nielsen, J. S., Vestergaard, P., Højlund, K., Jessen, N., Olsen, M. H., Sørensen, H. T., Thomsen, R. W. & Vaag, A., 2024, In: Diabetologia. 67, p. 1616–1629

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• Low-grade inflammation in persons with recently diagnosed type 2 diabetes: The role of abdominal adiposity and putative mediators

  Domazet, S. L., Olesen, T. B., Stidsen, J. V., Svensson, C. K., Nielsen, J. S., Thomsen, R. W., Jessen, N., Vestergaard, P., Andersen, M. K., Hansen, T., Brøns, C., Jensen, V. H., Vaag, A. A., Olsen, M. H. & Højlund, K., 2024, In: Diabetes, Obesity and Metabolism. 26, 6, p. 2092-2101

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  4 Citations (Scopus)

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• NK2R control of energy expenditure and feeding to treat metabolic diseases

  Sass, F., Ma, T., Ekberg, J. H., Kirigiti, M., Ureña, M. G., Dollet, L., Brown, J. M., Basse, A. L., Yacawych, W. T., Burm, H. B., Andersen, M. K., Nielsen, T. S., Tomlinson, A. J., Dmytiyeva, O., Christensen, D. P., Bader, L., Vo, C. T., Wang, Y., Rausch, D. M., Kristensen, C. K. & 27 others, Gestal-Mato, M., In het Panhuis, W., Sjøberg, K. A., Kernodle, S., Petersen, J. E., Pavlovskyi, A., Sandhu, M., Moltke, I., Jørgensen, M. E., Albrechtsen, A., Grarup, N., Babu, M. M., Rensen, P. C. N., Kooijman, S., Seeley, R. J., Worthmann, A., Heeren, J., Pers, T. H., Hansen, T., Gustafsson, M. B. F., Tang-Christensen, M., Kilpeläinen, T. O., Myers, M. G., Kievit, P., Schwartz, T. W., Hansen, J. B. & Gerhart-Hines, Z., 2024, In: Nature. 635, 8040, p. 987–1000 37 p.

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  2 Citations (Scopus)

• Precision stratification of prognostic risk factors associated with outcomes in gestational diabetes mellitus: a systematic review

  Semnani-Azad, Z., Gaillard, R., Hughes, A. E., Boyle, K. E., Tobias, D. K., Perng, W., Vilsbøll, T., Loos, R. J. F., Njølstad, P. R., Nakabuye, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 14 p., 9.

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  5 Citations (Scopus)

• Precision treatment of beta-cell monogenic diabetes: a systematic review

  Naylor, R. N., Patel, K. A., Kettunen, J. L. T., Männistö, J. M. E., Støy, J., Beltrand, J., Polak, M., Franks, P. W., Rich, S. S., Wagner, R., Vilsbøll, T., Vesco, K. K., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M., Redondo, M. J. & 31 others, Redman, L. M., Pratley, R. E., Pop-Busui, R., Pollin, T. I., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Murphy, R., Mohan, V., Misra, S., Meigs, J. B., Mathioudakis, N., Mathieu, C., Ma, R. C. W., Loos, R. J. F., Lim, S. S., Laffel, L. M., Kwak, S. H., Josefson, J. L., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 17 p., 145.

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• The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project Cohort and Biobank from 2010 Through 2023 - A Cohort Profile Update

  Kristensen, F. P. B., Nicolaisen, S. K., Nielsen, J. S., Christensen, D. H., Højlund, K., Beck-Nielsen, H., Rungby, J., Friborg, S. G., Brandslund, I., Christiansen, J. S., Vestergaard, P., Jessen, N., Olsen, M. H., Andersen, M. K., Hansen, T., Brøns, C., Vaag, A., Thomsen, R. W. & Sørensen, H. T., 2024, In: Clinical Epidemiology. 16, p. 641-656 16 p.

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• 2023

  A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

  Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, Albrechtsen, A., Moltke, I. & Hansen, T., 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.

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  9 Citations (Scopus)

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• Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes

  Hansen, A. L., Thomsen, R. W., Brøns, C., Svane, H. M. L., Jensen, R. T., Andersen, M. K., Hansen, T., Nielsen, J. S., Vestergaard, P., Højlund, K., Jessen, N., Olsen, M. H., Sørensen, H. T. & Vaag, A. A., 2023, In: Diabetologia. 66, p. 1680-1692 13 p.

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  7 Citations (Scopus)

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• Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review

  Felton, J. L., Griffin, K. J., Oram, R., Speake, C., Long, S. A., Onengut-Gumuscu, S., Rich, S. S., Monaco, G. S. F., Evans-Molina, C., DiMeglio, L. A., Ismail, H. M., Steck, A. K., Dabelea, D., Johnson, R. K., Urazbayeva, M., Gitelman, S., Wentworth, J. M., Redondo, M. J., Sims, E. K., Franks, P. W. & 31 others, Rich, S. S., Wagner, R., Vilsbøll, T., Vesco, K. K., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M., Redman, L. M., Pratley, R. E., Pop-Busui, R., Pollin, T. I., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Loos, R. J. F., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2023, In: Communications Medicine. 3, 1, 16 p., 130.

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• Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives

  Senftleber, N. K., Ramne, S., Moltke, I., Jørgensen, M. E., Albrechtsen, A., Hansen, T. & Andersen, M. K., 2023, In: Application of Clinical Genetics. 16, p. 31-39 9 p.

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  8 Citations (Scopus)

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• Genetics of metabolic traits in Greenlanders

  Thuesen, A. C. B., Andersen, M. K. & Hansen, T., 2023, In: Danish Medical Journal. 70, 12, 9 p., A05230332.

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• Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

  Williamson, A., Norris, D. M., Yin, X., Broadaway, K. A., Moxley, A. H., Vadlamudi, S., Wilson, E. P., Jackson, A. U., Ahuja, V., Andersen, M. K., Arzumanyan, Z., Bonnycastle, L. L., Bornstein, S. R., Bretschneider, M. P., Buchanan, T. A., Chang, Y-C., Chuang, L-M., Chung, R-H., Clausen, T. D., Damm, P. & 31 others, Delgado, G. E., de Mello, V. D., Dupuis, J., Dwivedi, O. P., Erdos, M. R., Silva, L. F., Frayling, T. M., Gieger, C., Goodarzi, M. O., Guo, X., Gustafsson, S., Hakaste, L., Hammar, U., Hatem, G., Herrmann, S., Højlund, K., Horn, K., Jonsson, A., Kovacs, P., Linneberg, A., Mathiesen, E., Rundsten, C. F., Stinson, S. E., Suleman, S., Vistisen, D., Witte, D. R., Hansen, T., Lind, L., Schwarz, P. E. H., Grarup, N. & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), 2023, In: Nature Genetics. 55, 6, p. 973-983 11 p.

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• High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity

  Stinson, S. E., Jonsson, A. E., Andersen, M. K., Lund, M. A. V., Holm, L. A., Fonvig, C. E., Huang, Y., Stankevič, E., Juel, H. B., Ängquist, L., Sørensen, T. I. A., Ongstad, E. L., Gaddipati, R., Grimsby, J., Rhodes, C. J., Pedersen, O., Christiansen, M., Holm, J. C. & Hansen, T., 2023, In: Journal of the American Heart Association. 12, 3, p. 538-544 22 p., e8145.

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• Participant characteristics in the prevention of gestational diabetes as evidence for precision medicine: a systematic review and meta-analysis

  Lim, S. S., Takele, W. W., Vesco, K. K., Redman, L. M., Hannah, W., Bonham, M. P., Chen, M., Chivers, S. C., Fawcett, A. J., Grieger, J. A., Habibi, N., Leung, G. K. W., Liu, K., Mekonnen, E. G., Pathirana, M., Quinteros, A., Taylor, R., Ukke, G. G., Zhou, S. J., Vilsbøll, T. & 9 others, Loos, R. J. F., Nakabuye, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2023, In: Communications Medicine. 3, 1, 11 p., 137.

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• Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity

  Andersen, M. K., Ängquist, L., Bork-Jensen, J., Jonsson, A. E., Stinson, S. E., Sandholt, C. H., Thodberg, M., Pikkupeura, L. M., Ongstad, E. L., Grarup, N., Astrup, A., Pedersen, O., Williams, K., Barrès, R., Sørensen, T. I. A., Linneberg, A., Grimsby, J., Rhodes, C. J. & Hansen, T., 2023, In: Diabetes Care. 46, 5, p. 985–992 9 p.

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  3 Citations (Scopus)

• Precision subclassification of type 2 diabetes: a systematic review

  Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, Stefan, N., Goodarzi, M. O., Ray, D., Selvin, E., Florez, J. C., Meigs, J. B., Udler, M. S. & ADA/EASD PMDI, 2023, In: Communications Medicine. 3, 19 p., 138.

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• Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

  Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, A. C. B., Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Andersen, M. K., Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, C., Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch-Ferré, M., Habibi, N., Hansen, T., Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, M., Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, R. J. F., Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, T., Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

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• The use of precision diagnostics for monogenic diabetes: a systematic review and expert opinion

  Murphy, R., Colclough, K., Pollin, T. I., Ikle, J. M., Svalastoga, P., Maloney, K. A., Saint-Martin, C., Molnes, J., Franks, P. W., Rich, S. S., Wagner, R., Vilsbøll, T., Vesco, K. K., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M. & 31 others, Redondo, M. J., Redman, L. M., Pratley, R. E., Pop-Busui, R., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Murphy, R., Mohan, V., Misra, S., Meigs, J. B., Mathioudakis, N., Mathieu, C., Ma, R. C. W., Loos, R. J. F., Lim, S. S., Laffel, L. M., Kwak, S. H., Josefson, J. L., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2023, In: Communications Medicine. 3, 1, 24 p., 136.

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• Treatment effect heterogeneity following type 2 diabetes treatment with GLP1-receptor agonists and SGLT2-inhibitors: a systematic review

  Young, K. G., McInnes, E. H., Massey, R. J., Kahkoska, A. R., Pilla, S. J., Raghavan, S., Stanislawski, M. A., Tobias, D. K., McGovern, A. P., Dawed, A. Y., Jones, A. G., Pearson, E. R., Dennis, J. M., Vilsbøll, T., Loos, R. J. F., Njølstad, P. R., Nakabuye, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C. & 4 others, Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PDMI, 2023, In: Communications Medicine. 3, 1, 131.

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  7 Citations (Scopus)

• Utility and precision evidence of technology in the treatment of type 1 diabetes: a systematic review

  Jacobsen, L. M., Sherr, J. L., Considine, E., Chen, A., Peeling, S. M., Hulsmans, M., Charleer, S., Urazbayeva, M., Tosur, M., Alamarie, S., Redondo, M. J., Hood, K. K., Gottlieb, P. A., Gillard, P., Wong, J. J., Hirsch, I. B., Pratley, R. E., Laffel, L. M., Mathieu, C., Vilsbøll, T. & 10 others, Loos, R. J. F., Njølstad, P. R., Nakabuye, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2023, In: Communications Medicine. 3, 1, 24 p., 132.

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  7 Citations (Scopus)
• 2022

  An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention

  Jørsboe, E., Andersen, M. K., Skotte, L., Stæger, F. F., Færgeman, N. J., Hanghøj, K., Santander, C. G., Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, M., Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, N., Moltke, I. & 2 others, Albrechtsen, A. & Hansen, T., 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.

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  11 Citations (Scopus)

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• A saturated map of common genetic variants associated with human height

  Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, T., Lin, K., Lull, K., Malden, D. E., Andersen, M. K., Appadurai, V., Bork-Jensen, J., Burgdorf, K. S., Hansen, T. F., Jonsson, A., Jorgensen, T., Liu, J., Mollehave, L. T., Smit, R. A. J., Zhao, J-H., Bisgaard, H., Bonnelykke, K., Dantoft, T. M., Grarup, N., Hansen, T., Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, A., Pedersen, O., Werge, T. M., Sun, Y., Loos, R. J. F., Winkler, T. W., 23andMe Res Team, VA Million Vet Program, DiscovEHR DiscovEHR MyCode Communi, eEMERGE Elect Med Records Genomics, LifeLines Cohort Study, PRACTICAL consortium & Understanding Soc Sci Grp, 2022, In: Nature. 610, p. 704–712

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• Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

  Duncan, C. J. A., Skouboe, M. K., Howarth, S., Hollensen, A. K., Chen, R., Børresen, M. L., Thompson, B. J., Spegarova, J. S., Hatton, C. F., Stæger, F. F., Andersen, M. K., Whittaker, J., Paludan, S. R., Jørgensen, S. E., Thomsen, M. K., Mikkelsen, J. G., Heilmann, C., Buhas, D., Øbro, N. F., Bay, J. T. & 17 others, Marquart, H. V., Morena, M. T. D. L., Klejka, J. A., Hirschfeld, M., Borgwardt, L., Forss, I., Masmas, T., Poulsen, A., Noya, F., Rouleau, G., Hansen, T., Zhou, S., Albrechtsen, A., Alizadehfar, R., Allenspach, E. J., Hambleton, S. & Mogensen, T. H., 2022, In: Journal of Experimental Medicine. 219, 6, 26 p., e20212427.

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  45 Citations (Scopus)

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• Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts

  Andersen, M. K., Skotte, L., Jørsboe, E., Polito, R., Stæger, F. F., Aldiss, P., Hanghøj, K., Waples, R. K., Santander, C. G., Grarup, N., Dahl-Petersen, I. K., Diaz, L. J., Overvad, M., Senftleber, N. K., Søborg, B., Larsen, C. V. L., Lemoine, C., Pedersen, O., Feenstra, B., Bjerregaard, P. & 9 others, Melbye, M., Jørgensen, M. E., Færgeman, N. J., Koch, A., Moritz, T., Gillum, M. P., Moltke, I., Hansen, T. & Albrechtsen, A., 2022, In: Gastroenterology. 162, 4, p. 1171-1182.e3

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  16 Citations (Scopus)

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• 2020

  Estimating narrow-sense heritability using family data from admixed populations

  Athanasiadis, G., Speed, D., Andersen, M. K., Appel, E. V. R., Grarup, N., Brandslund, I., Jørgensen, M. E., Larsen, C. V. L., Bjerregaard, P., Hansen, T. & Albrechtsen, A., 2020, In: Heredity. 124, 6, p. 751-762 12 p.

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  6 Citations (Scopus)

• New Insights into the Genetics of Latent Autoimmune Diabetes in Adults

  Andersen, M. K., 2020, In: Current Diabetes Reports. 20, 10 p., 43.

  Research output: Contribution to journal › Review › Research › peer-review
  14 Citations (Scopus)

• The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

  Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, Boyer, B. B., Jørgensen, M. E., Albrechtsen, A. & Hansen, T., 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.

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  7 Citations (Scopus)

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• 2019

  Genetics of Latent Autoimmune Diabetes in Adults

  Andersen, M. K. & Hansen, T., 2019, In: Current Diabetes Reviews. 15, 3, p. 194-198 5 p.

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  10 Citations (Scopus)
• 2018

  Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations

  Andersen, M. K., Grarup, N., Moltke, I., Albrechtsen, A. & Hansen, T., 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.

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  3 Citations (Scopus)

• Genetics of metabolic traits in Greenlanders: lessons from an isolated population

  Andersen, M. K. & Hansen, T., 2018, In: Journal of Internal Medicine. 284, 5, p. 464-477 14 p.

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  13 Citations (Scopus)

• Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

  Grarup, N., Moltke, I., Andersen, M. K., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, A., Pedersen, O., Jørgensen, M. E., Albrechtsen, A. & Hansen, T., 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

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• Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

  Grarup, N., Moltke, I., Andersen, M. K., Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, O. B., Andersson, R., Bjerregaard, P., Jørgensen, M. E., Albrechtsen, A. & Hansen, T., 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.

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  130 Citations (Scopus)
• 2016

  Genetics of Type 2 diabetes: the power of isolated populations

  Andersen, M. K., Pedersen, C-E. T., Moltke, I., Hansen, T., Albrechtsen, A. & Grarup, N., 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.

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  21 Citations (Scopus)

• Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders

  Andersen, M. K., Jørsboe, E., Sandholt, C. H., Grarup, N., Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, O. B., Moltke, I., Hansen, T. & Albrechtsen, A., 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.

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• 2015

  Recent Progress in the Understanding of Obesity: Contributions of Genome-Wide Association Studies

  Andersen, M. K. & Sandholt, C. H., Dec 2015, In: Current Obesity Reports. 4, 4, p. 401-10 10 p.

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  14 Citations (Scopus)
• 2014

  Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

  Andersen, M. K., Sterner, M., Forsén, T., Käräjämäki, A., Rolandsson, O., Forsblom, C., Groop, P. H., Lahti, K., Nilsson, P. M., Groop, L. & Tuomi, T., 1 Jan 2014, In: Diabetologia. 57, 9, p. 1859-1868 10 p.

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  53 Citations (Scopus)
• 2013

  Family history of Type 1 diabetes affects insulin secretion in patients with 'Type 2' diabetes

  Lundgren, V. M., Andersen, M. K., Isomaa, B. & Tuomi, T., 1 May 2013, In: Diabetic Medicine. 30, 5

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  9 Citations (Scopus)

• Zinc transporter type 8 autoantibodies (ZnT8A): Prevalence and phenotypic associations in latent autoimmune diabetes patients and patients with adult onset type 1 diabetes

  Andersen, M. K., Härkönen, T., Forsblom, C., Groop, P. H., Knip, M. & Tuomi, T., 1 Jun 2013, In: Autoimmunity. 46, 4, p. 251-258 8 p.

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  23 Citations (Scopus)
• 2012

  Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study

  Andersen, M. K., Lundgren, V., Isomaa, B., Groop, L. & Tuomi, T., 1 Jul 2012, In: European Journal of Endocrinology. 167, 1, p. 27-33 7 p.

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  8 Citations (Scopus)
• 2010

  Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

  Andersen, M. K., Lundgren, V., Turunen, J. A., Forsblom, C., Isomaa, B., Groop, P. H., Groop, L. & Tuomi, T., 1 Sep 2010, In: Diabetes Care. 33, 9, p. 2062-2064 3 p.

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  71 Citations (Scopus)
• 2008

  The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects

  Grarup, N., Andreasen, C. H., Andersen, M. K., Albrechtsen, A., Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, O., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.

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  27 Citations (Scopus)
• 2007

  Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

  Grarup, N., Andersen, M. K., Andreasen, C. H., Albrechtsen, A., Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, T. & Pedersen, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.

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  57 Citations (Scopus)

• The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites

  Jensen, D. P., Andersen, M. K., Hansen, L., Eiberg, H., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, O. & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.

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  59 Citations (Scopus)