Research output per year
Research output per year
PhD
Universitetsparken 2, 2100 København Ø, 13 Bygning 13, 13-6-616
Universitetsparken 2
2100 København Ø
Research activity per year
Short prosentation
Mingshi Yang received his Ph.D. from Shenyang Pharmaceutical University, China, in 2003, and then conducted postdoctoral research in Gifu Pharmaceutical University, Japan (2003-2005) and The Danish University of Pharmaceutical Sciences (2005-2006), respectively. After having worked as a research scientist in Novo Nordisk A/S (2006-2009), he took up the current position in University of Copenhagen in June 2009. His research has been focused on engineering micro/nanoparticles to improve delivery of both biopharmaceuticals and small molecule therapeutics via various administration routes. He is a board member of two international peer-reviewed scientific journals, and Chinese Society of Particuology - Bioparticle Association, also serves as a reviewer for more than 20 international scientific journals. He received a senior visiting scholarship from Fudan University (2014-2015), and received Pan Deng Scholar from Liaoning Province, China, 2015.
Micro/nanoparticulate systems may provide bio-actives with a few functionalities, e.g. targeted delivery, extended effects, improved stability, enhanced solubility, enhanced bioavailability and reduced side effects, which are desired for various medical uses such as drug delivery, tissue engineering and new therapies. Mechanistic understanding of the formation process of the micro/nanoparticles and their impact on bio-environment is essential for rational design of these systems. My research interests include understanding physical and chemical mechanisms that determine the engineering of aforementioned micro/nanoparticulate systems with optimal functionalities, the interplay between the micro/nanoparticulates and bio-membranes or cells, as well as the mechanisms that control the release of the bio-actives from the micro/nanoparticulate systems.
The current research is focused on engineering of micro/nanoparticles or nano-composite particles via wet chemistry or atomization technologies including spray-drying, spray freeze-drying and electrospraying/electrospinning for respiratory, peroral or subcutaneous administration of poorly water-soluble drugs, protein/peptide drugs and siRNA. Another emphasis of the current research is placed on characterization of the physical and chemical stability of the protein and peptide drugs upon the processing.
Projects ongoing:
PhD projects
Postdoc project
PhD projects supervised
Master students supervised
2013
2012
2011
2010
2009
Adjunct Professor, Shenyang Pharmaceutical University, China, 2015 -
Associate Professor, Department of Pharmacy, School of Pharmaceutical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark, 2012 -
Associate Professor, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Denmark, 2009 - 2012
Research Scientist, Novo Nordisk A/S, Denmark, 2006 - 2009
Postdoctoral Researcher, Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, Denmark, 2005 - 2006
Postdoctoral Researcher, Gifu Pharmaceutical University, Japan, 2003 - 2005
Ph.D. (Pharmaceutics), Shenyang Pharmaceutical University, China, 2003
Research and teaching assistant, Yanbian Medical College, Yanbian University, China 1997 - 1999
MSc, Yanbian Medical College, Yanbian University, China 1997
BSc, Yanbian Medical College, Yanbian University, China 1994
Adjunct professor, Shenyang Pharmaceutical University
1 Jan 2015 → …
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Review › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review