Morten Grunnet

EmailMGRUlundbeckcom

Universitetsparken 2
2100 København Ø

Primary fields of research

Morten Grunnet har viden om hjertets fysiologi - især om de ionkanaler, der tillader forskellige stoffer at passerer cellemembranen, hvoraf nogle er afgørende for, at hjertet kan slå.

Keywords

Faculty of Health and Medical Sciences
Cardiovascular Diseases
Arteriosclerosis

109 Journal article
1 Conference abstract in journal
1 Conference article
1 Review
More
- 1 Other contribution

Na_V1.5 or K_Ca2 channel blockade does not increase arrhythmia risk in hypokalemic rabbit hearts, unlike K_V11.1 inhibition with dofetilide
Yan, Y., Abildgaard, L., Skarsfeldt, M. A., Bomholtz, S. H., Sørensen, U., Holst, A. G., Grunnet, M., Diness, J. G. & Bentzen, B. H., 2025, In: IJC Heart and Vasculature. 59, 8 p., 101699.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
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2 Downloads (Pure)
A phase 1 trial of AP30663, a K_Ca2 channel inhibitor in development for conversion of atrial fibrillation
Yfanti, C., Vestbjerg, B., van't Westende, J., Edvardsson, N., Monfort, L. M., Olesen, M. S., Bentzen, B. H., Grunnet, M., Eveleens Maarse, B. C., Diness, J. G., Kemme, M. J. B., Sørensen, U., Moerland, M., van Esdonk, M. J., Klaassen, E. S., Gal, P. & Holst, A. G., 2024, In: British Journal of Clinical Pharmacology. 90, 4, p. 1027-1035
Research output: Contribution to journal › Journal article › Research › peer-review

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1 Citation (Scopus)

25 Downloads (Pure)
Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial
Holst, A. G., Tomcsányi, J., Vestbjerg, B., Grunnet, M., Sørensen, U. S., Diness, J. G., Bentzen, B. H., Edvardsson, N., Hohnloser, S. H., Bhatt, D. L. & Dorian, P., 2024, In: Nature Medicine. 30, 1, p. 106-111
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
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19 Citations (Scopus)

9 Downloads (Pure)
Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing
Citerni, C., Kirchhoff, J., Olsen, L. H., Sattler, S. M., Gentilini, F., Forni, M., Zannoni, A., Grunnet, M., Edvardsson, N., Bentzen, B. H. & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.
Research output: Contribution to journal › Journal article › Research › peer-review

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16 Citations (Scopus)

152 Downloads (Pure)
Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction
Citerni, C., Kirchhoff, J., Olsen, L. H., Sattler, S. M., Grunnet, M., Edvardsson, N., Bentzen, B. H. & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 11 p., 556.
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2 Citations (Scopus)

87 Downloads (Pure)
The K_Ca2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs
Diness, J. G., Kirchhoff, J. E., Speerschneider, T., Abildgaard, L., Edvardsson, N., Sorensen, U. S., Grunnet, M. & Bentzen, B. H., 2020, In: Frontiers in Pharmacology. 11, 9 p., 159.
Research output: Contribution to journal › Journal article › Research › peer-review

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34 Citations (Scopus)

85 Downloads (Pure)
Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model
Lubberding, A. F., Sattler, S. M., Grunnet, M., Sørensen, U. S., Tfelt-Hansen, J. & Jespersen, T., Oct 2019, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21, 10, p. 1584–1593
Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)
Impact of arrhythmogenic calmodulin variants on small conductance Ca²⁺-activated K⁺ (SK3) channels
Saljic, A., Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, M., Berchtold, M. W. & Jespersen, T., 2019, In: Physiological Reports. 7, 19, 13 p., e14210.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
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9 Citations (Scopus)

109 Downloads (Pure)

Morten Grunnet

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Primary fields of research

Keywords

Collaborations and top research areas from the last five years

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Na_V1.5 or K_Ca2 channel blockade does not increase arrhythmia risk in hypokalemic rabbit hearts, unlike K_V11.1 inhibition with dofetilide

A phase 1 trial of AP30663, a K_Ca2 channel inhibitor in development for conversion of atrial fibrillation

Inhibition of the KCa2 potassium channel in atrial fibrillation: a randomized phase 2 trial

Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing

Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction

The K_Ca2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

Impact of arrhythmogenic calmodulin variants on small conductance Ca²⁺-activated K⁺ (SK3) channels

Morten Grunnet

Personal profile

Primary fields of research

Keywords

Collaborations and top research areas from the last five years

Research output