Research output per year
Research output per year
Personal profile
Current research
- Impact of the Pseudomonas aeruginosa biofilm extracellular matrix on the host immune response
- Regulation of extracellular matrix production in P. aeruginosa by the second messenger cyclic di-GMP
- Modification of the biochemical properties of the P. aeruginosa extracellular matrix
Primary fields of research
- Bacterial biofilm biology
- Host immune responses to biofilms
- Regulation of biofilm formation
Fields of interest
Bacterial biofilm biology. In particular the molecular mechanisms governing the biofilm developmental process.
Knowledge of languages
Fluent in English and Danish. Limited knowledge of German.
Education/Academic qualification
Health Sciences, PhD degree, University of Copenhagen
Award Date: 28 Jun 2012
Biotechnology, Master of Science in Engineering, Technical University of Denmark
Award Date: 29 Aug 2008
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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High efficacytreatment of murine Pseudomonas aeruginosa catheter-associated urinary tract infections using the c-di-GMP modulating anti-biofilmcompound Disperazol in combination with ciprofloxacin
Hultqvist, L. D., Andersen, J. B., Nilsson, C. M., Jansen, C. U., Rybtke, M., Jakobsen, T. H., Nielsen, T. E., Qvortrup, K., Moser, C., Graz, M., Qvortrup, K., Tolker-Nielsen, T. & Givskov, M., 2024, In: Antimicrobial Agents and Chemotherapy. 68, 6, 16 p., e01481-23.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump
Kristensen, R., Andersen, J. B., Rybtke, M., Jansen, C. U., Fritz, B. G., Kiilerich, R. O., Uhd, J., Bjarnsholt, T., Qvortrup, K., Tolker-Nielsen, T., Givskov, M. & Jakobsen, T. H., 2024, In: Antimicrobial Agents and Chemotherapy. 68, 2Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)15 Downloads (Pure) -
Microbial Primer: The catalytic biofilm matrix
Goltermann, L., Shahryari, S., Rybtke, M. & Tolker-Nielsen, T., 2024, In: Microbiology (United Kingdom). 170, 8, 5 p., 001497.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
Role of extracellular matrix components in biofilm formation and adaptation of Pseudomonas ogarae F113 to the rhizosphere environment
Blanco-Romero, E., Garrido-Sanz, D., Durán, D., Rybtke, M., Tolker-Nielsen, T., Redondo-Nieto, M., Rivilla, R. & Martín, M., 2024, In: Frontiers in Microbiology. 15, 12 p., 1341728.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
Effects of antibiotic treatment and phagocyte infiltration on development of Pseudomonas aeruginosa biofilm—Insights from the application of a novel PF hydrogel model in vitro and in vivo
Wu, H., Song, L., Yam, J. K. H., Plotkin, M., Wang, H., Rybtke, M., Seliktar, D., Kofidis, T., Høiby, N., Tolker-Nielsen, T., Song, Z. & Givskov, M., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 826450.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)31 Downloads (Pure) -
Transcription of the Alginate Operon in Pseudomonas aeruginosa Is Regulated by c-di-GMP
Liang, Z., Rybtke, M., Kragh, K. N., Johnson, O., Schicketanz, M., Zhang, Y. E., Andersen, J. B. & Tolker-Nielsen, T., 2022, In: Microbiology Spectrum. 10, 4, 13 p., e00675-22.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)33 Downloads (Pure) -
Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms
Andersen, J. B., Hultqvist, L. D., Jansen, C. U., Jakobsen, T. H., Nilsson, M., Rybtke, M., Uhd, J., Fritz, B. G., Seifert, R., Berthelsen, J., Nielsen, T. E., Qvortrup, K., Givskov, M. & Tolker-Nielsen, T., 2021, In: npj Biofilms and Microbiomes. 7, 13 p., 59.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile43 Citations (Scopus)49 Downloads (Pure) -
Immune Responses to Pseudomonas aeruginosa Biofilm Infections
Moser, C., Jensen, P. Ø., Thomsen, K., Kolpen, M., Rybtke, M., Lauland, A. S., Trøstrup, H. & Tolker-Nielsen, T., 2021, In: Frontiers in Immunology. 12, 625597.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile86 Citations (Scopus)48 Downloads (Pure)