Personal profile
Short presentation
Morten Meldal was rewarded the Nobel Prize in Chemistry 2022.
- Morten Meldal is a professor at the University of Copenhagen and head of the Center of Evolutionary Chemical Biology.
- He has served as the Deputy Head of Department for Education (VILU) at UCPH's Department of Chemistry.
- He has a unique influence on methods used in peptide and combinatorial chemistry. His specialties span combinatorial chemistry, click chemistry, polymer chemistry, organic synthesis, automation in synthesis, artificial receptors and enzymes, nano assays, biomolecular recognition, enzyme activity, cellular assays, molecular immunology, nano scale MS and NMR, encoding.
- He founded the Society of Combinatorial Sciences, of which he is also president.
- He has published more than 300 publications and holds 21 patents.
- He is also the company founder and CSO of Betamab, a company that conducts biotechnology and pharmacological research, diagnostics and pharmaceutical development.
CV
University Education:
| 1983 | PhD | Institute of Organic Chemistry, Technical University of Denmark (DTU) |
| 1981 | M.Sc. | Chemical Engineering, DTU |
| 1896 | Postdoc | Cambridge University |
Positions/Affiliations:
- 2019 - 2020 Vice-Institute Director of Teaching, Department of Chemistry University of Copenhagen (UCPH)
- 2013 - 2018 Center Director, Center of Evolutionary Chemical Biology, UCPH
- 2011 - Professor in Chemistry, Department of Chemistry, UCPH
- 1988 - 2011 Professor & Director, SPOCC Centre, Carlsberg Laboratory, Copenhagen, Denmark
- 1996 - 2007 Ajunct Professor at DTU and at University of Pharmaceutical Sciences, Copenhagen.
- 1986 - 1988 Postdoc H. C. Ørsted Institute, UCPH
- 1985 - 1986 Postdoc, Laboratory of Molecular Biology, Cambridge, England (Robert C. Sheppard)
- 1983 - 1985 Postdoc Technical University of Denmark
Selected recognitions and Awards:
- 2022 The Nobel Prize in Chemistry 2022
- 2019 Top 3 candidate for the Nobel prize 2019
- 2011 Vincent du Vigneaud Award, American Peptide Society
- 2009 Ralph F. Hirschmann Award, American Chemical Society
- 1997 Bjerrum-Brønsted-Lang lecture in Danish Royal Society of Science and Letters
- 1996 Niels Bjerrum Gold Medal in Chemistry, Denmark
- 1996 The Leonidas Zervas Award, European Peptide Society
- 1996 NKT-Award, Danish Society of Chemistry
- 1995 Mitzutani Foundation Award, Japan
- 1990 Danish Chemistry Award, Danish Society of Chemistry
- 1988 Kirstine Meyers Award, Kirstine Meyers Foundation, Denmark
Large research awards:
- 2013 Research Award from Applied Biomimetic / HT
- 2013 Research Award from University of Copenhagen
- 2012 Research Award from Lundbeck Foundation
- 2012 Research Award from Novonordisk/HT
- 2007 Research Award from the EU-CAMP Research Program
- 1997 Research Award from the Danish National Research Foundation (renewed 2002 and 4)
- 1997 Research Award from the Danish Cancer Society
- 1995 Research Award from the EU-INCO-DC program
- 1992 Research Award from the EU-Science Program
Start-up companies:
- 2000 Cofounder of Combio A/S
- 2002 Cofounder of Versamatrix A/S
- 2019 Cofounder of Betamab APS
Commission of trust:
- 2010 Chairman and Organizer of the 31'st European Peptide Symposium
- 2003 Chairman and Organizer of 2’nd Symposium of Combinatorial Sciences
- 2000 - Elected member of The Royal Danish Academy of Sciences and Letters
- 1999 - Chairman and Co-founder of the Society of Combinatorial Sciences
- 1992 - 2004 Board member of the European Peptide Society
Primary fields of research
- Computational chemistry
- Chemical biology
- Organic chemistry
- Polymer science
- Combinatorial chemistry
- Enzymology
- Protein chemistry
- GPCR’s
- Structural chemistry
- Immunology
- Molecular recognition
- Catalysis
- Nanomaterials.
Keywords
- Faculty of Science
- Computational Chemistry
- Chemical biology
- Organic chemistry
- Polymer science
- Combinatorial chemistry
- Enzymology
- Protein Chemistry
- GPCRs
- Structural chemistry
- Immunology
- Molecular recognition
- Catalysis
- Nanomaterials
Collaborations and top research areas from the last five years
Research output
-
Click-Cyclized Cell Penetrating Peptides Containing Hydrophobic Proline Derivatives for Efficient Intracellular Delivery
Zhang, Y., Kæstel-Hansen, J., Teze, D., Huang, G., Schoffelen, S., Lisby, M., Zhang, M., Hatzakis, N. S. & Meldal, M., 2025, In: Angewandte Chemie - International Edition. 64, 50, 10 p., e202504862.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Green Resins for All: Sustainable Preparation of PEGA Resin for Peptide and Protein Synthesis and Immobilization
Ramsing, M. L., Warming, C. & Meldal, M., 2025, In: ACS Applied Materials and Interfaces. 17, 17, p. 25764−25773 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Parthenolide disrupts mitosis by inhibiting ZNF207/BUGZ-promoted kinetochore-microtubule attachment
Eibes, S., Lakshmi, R. B., Rajendraprasad, G., Weinert, B. T., Kamounah, F. S., Gamon, L. F., Rodriguez-Calado, S., Meldal, M., Davies, M. J., Pittelkow, M., Choudhary, C. & Barisic, M., 2025, In: EMBO Journal. 44, p. 3764-3793 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)7 Downloads (Pure) -
Hydrodynamic Control of Alzheimer Aβ Fibrillation with Glucosaminic Acid Containing Click-Cyclized β-Bodies
Zhang, Y., Borch, L. A., Fischer, N. H. & Meldal, M., 2024, In: Journal of the American Chemical Society. 164, 4, p. 2654–2662 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus) -
Cascade autohydrolysis of Alzheimer's Aβ peptides
Wolfram, M., Tiwari, M. K., Hassenkam, T., Li, M., Bjerrum, M. J. & Meldal, M., 2023, In: Chemical Science. 14, 19, p. 4986–4996 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)129 Downloads (Pure) -
Development of Selective ADAMTS-5 Peptide Substrates to Monitor Proteinase Activity
Fowkes, M. M., Troeberg, L., Brennan, P. E., Vincent, T. L., Meldal, M. & Lim, N. H., 2023, In: Journal of Medicinal Chemistry. 66, 5, p. 3522-3539 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)57 Downloads (Pure) -
Attachment of cyclodextrin acids to PEGA resin and study of binding with fluorescence microscopy
Langhorn, L. M., Wang, B., Meldal, M. & Bols, M., 2021, In: Bioorganic & Medicinal Chemistry Letters. 43, 4 p., 128060.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)125 Downloads (Pure) -
Combinatorial library screening for selective ADAMTS-5 peptide substrates to study aggrecanase activity
Fowkes, M. M., Vincent, T. L., Brennan, P. E., Meldal, M. & Lim, N. H., Aug 2021, p. A11-A12. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review