Research output per year
Research output per year
- 1 - 50 out of 60 results
Search results
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2023
Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury
Rusiecka, O. M., Molica, F., Nielsen, M. S., Tollance, A., Morel, S., Frieden, M., Chanson, M., Boengler, K. & Kwak, B. R., 2023, In: Cardiovascular Research. 119, 13, p. 2342-2354Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)13 Downloads (Pure) -
Phase-2 Re-Entry in Brugada Syndrome: More to Understand Than “Just” Ito
Kanters, J. K. & Nielsen, M. S., 2023, In: JACC: Clinical Electrophysiology. 9, 12, p. 2475-2476Research output: Contribution to journal › Editorial › Research › peer-review
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The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes
Nielsen, M. S., van Opbergen, C. J. M., van Veen, T. A. B. & Delmar, M., 2023, In: Physiological Reviews. 103, 3, p. 2271-2319Research output: Contribution to journal › Review › Research › peer-review
12 Citations (Scopus) -
2021
Connexins and Pannexins in Cardiovascular Disease
Kwak, B. R. & Nielsen, M. S., 2021, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside. Jalife, J. & Stevenson, W. G. (eds.). 8 ed. Philadelphia, PA, USA: Elsevier, p. 168-177 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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2020
Pannexin 1 activation and inhibition is permeant-selective
Nielsen, B. S., Toft-Bertelsen, T. L., Lolansen, S. D., Anderson, C. L., Nielsen, M. S., Thompson, R. J. & MacAulay, N., 2020, In: The Journal of Physiology. 598, 2, p. 361-379 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, M., Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, M. S., Bentzen, B. H., Olsen, J. V. & Lundby, A., 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)43 Downloads (Pure) -
2019
Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se
Jensen, C. F., Bartels, E. D., Braunstein, T. H., Nielsen, L. B., Holstein-Rathlou, N-H., Axelsen, L. N. & Nielsen, M. S., Apr 2019, In: Physiological Reports. 7, 7, 13 p., e14049.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)58 Downloads (Pure) -
Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts
George, S. A., Hoeker, G., Calhoun, P. J., Entz, M., Raisch, T. B., King, D. R., Khan, M., Baker, C., Gourdie, R. G., Smyth, J. W., Nielsen, M. S. & Poelzing, S., 1 Feb 2019, In: American Journal of Physiology: Heart and Circulatory Physiology. 316, 4, p. H849-H861Research output: Contribution to journal › Journal article › Research › peer-review
Open Access26 Citations (Scopus) -
Structural determinants underlying permeant discrimination of the Cx43 hemichannel
Nielsen, B. S., Zonta, F., Farkas, T., Litman, T., Nielsen, M. S. & Macaulay, N., 2019, In: Journal of Biological Chemistry. 294, 45, p. 16789-16803 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile17 Citations (Scopus)45 Downloads (Pure) -
2018
Connexins and Disease
Delmar, M., Laird, D. W., Naus, C. C., Nielsen, M. S., Verselis, V. K. & White, T. W., 2018, In: Cold Spring Harbor perspectives in biology. 10, 9, p. 1-18 a029348.Research output: Contribution to journal › Journal article › Research › peer-review
46 Citations (Scopus) -
Genetically modified animals as tools to personalize the study of arrhythmia mechanisms and treatment
Cerrone, M., Nielsen, M. S. & Delmar, M., 2018, ESC CardioMed. Camm, A. J., Lüscher, T. F., Maurer, G. & Serruys, P. W. (eds.). 3 ed. Oxford University PressResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Probenecid inhibits α-adrenergic receptor-mediated vasoconstriction in the human leg vasculature
Nyberg, M. P., Piil, P. B., Kiehn, O. T., Maagaard, C., Jørgensen, T. S., Egelund, J., Isakson, B. E., Nielsen, M. S., Gliemann, L. & Hellsten, Y., 2018, In: Hypertension. 71, 1, p. 151-159 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
33 Citations (Scopus) -
Protein⁻Protein Interactions with Connexin 43: Regulation and Function
Sorgen, P. L., Trease, A. J., Spagnol, G., Delmar, M. & Nielsen, M. S., 10 May 2018, In: International Journal of Molecular Sciences. 19, 5, 21 p., 1428.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile37 Citations (Scopus)132 Downloads (Pure) -
Uremia increases QRS duration after β-adrenergic stimulation in mice
Thomsen, M. B., Nielsen, M. S., Aarup, A., Bisgaard, L. S. & Pedersen, T. X., 1 Jul 2018, In: Physiological Reports. 6, 13, 13 p., e13720.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)142 Downloads (Pure) -
2017
Astrocytic connexin hemichannels are regulated by PKC phosphorylation in an isoform-specific manner
MacAulay, N., Alstrom, J. S., Hansen, D. B. & Nielsen, M. S., 2017, In: Glia. 65, S1, p. E64-E64 S17-01.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Open Access -
Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics
Nielsen, B. S., Hansen, D. B., Ransom, B. R., Nielsen, M. S. & MacAulay, N., Sep 2017, In: Neurochemical Research. 42, 9, p. 2537–2550 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Thorsen, K., Dam, V. S., Kjaer-Sorensen, K., Pedersen, L. N., Skeberdis, V. A., Jurevicius, J., Treinys, R., Petersen, I. M. B. S., Nielsen, M. S., Oxvig, C., Morth, J. P., Matchkov, V. V., Aalkjaer, C., Bundgaard, H. & Jensen, H. K., 22 Nov 2017, In: Nature Communications. 8, 10 p., 1696.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile74 Citations (Scopus)273 Downloads (Pure) -
Permeant-specific gating of connexin 30 hemichannels
Nielsen, B. S., Alstrom, J. S., Nicholson, B., Nielsen, M. S. & Macaulay, N., 2017, In: Journal of Biological Chemistry. 292, 49, p. 19999-20009Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
T-type Ca(2+) channels and Autoregulation of Local Blood Flow
Jensen, L. J., Nielsen, M. S., Salomonsson, M. & Sørensen, C. M., 2017, In: Channels (Austin). 11, 3, p. 183-195 13 p.Research output: Contribution to journal › Review › Research › peer-review
Open Access7 Citations (Scopus) -
T-type Ca2+ channels and autoregulation of local blood flow
Jensen, L. J., Nielsen, M. S., Salomonsson, M. & Sørensen, C. M., 4 May 2017, In: Channels (Austin). 11, 3, p. 183-195Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Unsupervised Idealization of Ion Channel Recordings by Minimum Description Length: Application to Human PIEZO1-Channels
Gnanasambandam, R., Nielsen, M. S., Nicolai, C., Sachs, F., Hofgaard, J. P. & Dreyer, J. K., 2017, In: Frontiers in Neuroinformatics. 11, 16 p., 31.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)237 Downloads (Pure) -
2016
Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43
Morel, S., Christoffersen, C., Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, M. S., Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
54 Citations (Scopus) -
2015
Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium
Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, S. H., Nielsen, M. S., Grunnet, M., Bentzen, B. H. & Jespersen, T., Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
26 Citations (Scopus) -
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
Axelsen, L. N., Callø, K., Braunstein, T. H., Riemann, M., Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, K. B., Bartels, E. D., Baandrup, U., Jespersen, T., Nielsen, L. B., von Holstein-Rathlou, N-H. & Nielsen, M. S., 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Citations (Scopus)372 Downloads (Pure) -
Gap junctions-guards of excitability
Stroemlund, L. W., Jensen, C. F., Qvortrup, K., Delmar, M. & Nielsen, M. S., 1 Jun 2015, In: Biochemical Society Transactions. 43, 3, p. 508-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
18 Citations (Scopus) -
Isoform-specific phosphorylation-dependent regulation of connexin hemichannels
Alstrøm, J. S., Hansen, D. B., Nielsen, M. S. & MacAulay, N., 15 Nov 2015, In: Journal of Neurophysiology. 114, 5, p. 3014-22 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Protein kinase C-dependent regulation of connexin43 gap junctions and hemichannels
Alstrøm, J. S., Stroemlund, L. W., Nielsen, M. S. & MacAulay, N., Jun 2015, In: Biochemical Society Transactions. 43, 3, p. 519-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access13 Citations (Scopus) -
Sympathetic vasoconstriction takes an unexpected pannexin detour
Schak Nielsen, M., 17 Feb 2015, In: Science Signaling. 8, 364, p. 1-2 2 p., fs4.Research output: Contribution to journal › Comment/debate › Research › peer-review
4 Citations (Scopus) -
2014
Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels
Hansen, D. B., Ye, Z-C., Calloe, K., Braunstein, T. H., Hofgaard, J. P., Ransom, B. R., Nielsen, M. S. & MacAulay, N., 19 Sep 2014, In: The Journal of Biological Chemistry. 289, 38, p. 26058-73 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
35 Citations (Scopus) -
Distinct permeation profiles of the connexin 30 and 43 hemichannels
Hansen, D. B., Braunstein, T. H., Nielsen, M. S. & Macaulay, N., 17 Apr 2014, In: FEBS Letters. 588, 8, p. 1446-57 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
56 Citations (Scopus) -
2013
Managing the complexity of communication: regulation of gap junctions by post-translational modification
Axelsen, L. N., Callø, K., von Holstein-Rathlou, N-H. & Nielsen, M. S., Oct 2013, In: Frontiers in Pharmacology. 4, p. 1-18 18 p., 130.Research output: Contribution to journal › Journal article › Research › peer-review
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Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats
Olsen, K. B., Axelsen, L. N., Braunstein, T. H., Sørensen, C. M., Andersen, C. B., Ploug, T., von Holstein-Rathlou, N-H. & Nielsen, M. S., 2013, In: Cardiovascular Diabetology. 12, p. 19 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
25 Citations (Scopus) -
2012
Estimation of the effective intercellular diffusion coefficient in cell monolayers coupled by gap junctions
Olesen, N. E., Hofgaard, J. P., von Holstein-Rathlou, N-H., Nielsen, M. S. & Jacobsen, J. C. B., 2012, In: European Journal of Pharmaceutical Sciences. 46, 4, p. 222-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus) -
Gap Junctions
Nielsen, M. S., Axelsen, L. N., Sorgen, P., Verma, V., Mario, D. & von Holstein-Rathlou, N-H., 2012, In: Comprehensive Physiology. 2, p. 1981-2035Research output: Contribution to journal › Review › Research › peer-review
342 Citations (Scopus) -
Lateralized gap junctions in pulmonary hypertension - lost but not alone
Nielsen, M. S., 2012, In: Heart Rhythm. 9, 7, p. 1141-1142 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2011
Angiotensin II does not acutely regulate conduction velocity in rat atrial tissue
Olsen, K. B., Braunstein, T. H., Sørensen, C. M., Axelsen, L. N., Holstein-Rathlou, N-H. & Nielsen, M. S., 6 Jul 2011, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 71, 6, p. 492 499 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
Mollerup, S., Hofgaard, J. P., Braunstein, T. H., Kjenseth, A., Leithe, E., Rivedal, E., von Holstein-Rathlou, N-H. & Nielsen, M. S., 21 Sep 2011, In: Cell Communication & Adhesion (Print Edition). 18, 4, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling
Bonde, M. M., Olsen, K. B., Erikstrup, N., Speerschneider, T., Lyngsø, C., Haunsø, S., Nielsen, M. S., Sheikh, S. P. & Hansen, J. L., 2011, In: Regulatory Peptides. 167, 1, p. 21-25 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
19 Citations (Scopus) -
2010
Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles (American Journal of Physiology - Regulatory Integrative and Comparative Physiology (2008) 295, (R840-R847) DOI:10.1152/ajpregu.00491.2007)
Sorensen, C. M., Salomonsson, M., Braunstein, T. H., Nielsen, M. S. & Holstein-Rathlou, N. H., 1 Jan 2010, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 1Research output: Contribution to journal › Comment/debate › Research › peer-review
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2009
Myocyte-fibroblast interactions--risky connections
Nielsen, M. S., 2009, In: Heart Rhythm. 6, 11, p. 1650-1 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Phosphorylation of connexin43 on serine 306 regulates electrical coupling
Procida, K., Jørgensen, L., Schmitt, N., Delmar, M., Taffet, S. M., Holstein-Rathlou, N-H., Nielsen, M. S. & Braunstein, T. H., 2009, In: Heart Rhythm. 6, 11, p. 1632-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
49 Citations (Scopus) -
Quantification of gap junctional intercellular communication based on digital image analysis
Hofgaard, J. P., Mollerup, S., Holstein-Rathlou, N-H. & Nielsen, M. S., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 297, 2, p. R243-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus) -
2008
Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles.
Sørensen, C. M., Salomonsson, M., Braunstein, T. H., Nielsen, M. S. & Holstein-Rathlou, N-H., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 295, 3, p. R840-7Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes
Hofgaard, J. P., Banach, K., Mollerup, S., Jørgensen, H. K., Olesen, S. P., Holstein-Rathlou, N-H. & Nielsen, M. S., 2008, In: Pflügers Archiv: European Journal of Physiology. 457, 2, p. 303-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
RXP-E: a connexin43-binding peptide that prevents action potential propagation block
Lewandowski, R., Procida, K., Vaidyanathan, R., Coombs, W., Jalife, J., Nielsen, M. S., Taffet, S. M. & Delmar, M., 2008, In: Circulation Research. 103, 5, p. 519-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
35 Citations (Scopus) -
Synopsis of the International Gap Junction Conference in Elsinore, Denmark August 5-9, 2007.
Willecke, K. & Nielsen, M. S., 2008, In: Cell Communication & Adhesion (Print Edition). 14, 6, p. 251-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2007
Increasing gap junctional coupling: a tool for dissecting the role of gap junctions.
Axelsen, L. N., Haugan, K., Stahlhut, M., Kjølbye, A-L., Hennan, J. K., Petersen, J. S., Nielsen, M. S. & Holstein-Rathlou, N-H., 2007, In: Journal of Membrane Biology. 216, 1, p. 23-35 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.
Calloe, K., Nielsen, M. S., Grunnet, M., Schmitt, N. & Jorgensen, N. K., 2007, In: BBA General Subjects. 1773, 6, p. 764-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
18 Citations (Scopus) -
2006
Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).
Axelsen, L. N., Stahlhut, M., Mohammed, S., Larsen, B. D., Nielsen, M. S., Andersen, S., Jensen, O. N., Hennan, J. K., Kjølbye, A. L. & Holstein-Rathlou, N-H., 2006, In: Journal of Molecular and Cellular Cardiology. 40, 6, p. 790-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
118 Citations (Scopus) -
Treatment with the gap junction modifier rotigaptide (ZP123) reduces infarct size in rats with chronic myocardial infarction.
Haugan, K., Marcussen, N., Kjølbye, A. L., Nielsen, M. S., Hennan, J. K. & Petersen, J. S., 2006, In: Journal of Cardiovascular Pharmacology. 47, 2, p. 236-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
33 Citations (Scopus)