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Research output

Research output per year 2015 2016 2017 2020 2022 2023

• 640 Citations
• 10 Journal article
• 3 Review
• 1 Comment/debate
• 1 Conference abstract in journal

Research output per year

Research output per year

Search results

• 2023

  LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

  Kaastrup, K., Gillberg, L., Mikkelsen, S. U., Ørskov, A. D., Schöllkopf, C., Mortensen, B. K., Porse, B., Hansen, J. W. & Grønbæk, K., 2023, In: Clinical Epigenetics. 15, 13 p., 91.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  15 Downloads (Pure)
• 2022

  Inflammatory Cytokine Profiles Do Not Differ Between Patients With Idiopathic Cytopenias of Undetermined Significance and Myelodysplastic Syndromes

  Nielsen, A. B., Hansen, J. W., Ørskov, A. D., Dimopoulos, K., Salem, M., Grigorian, M., Bruunsgaard, H. K. & Grønbæk, K., 2022, In: HemaSphere. 6, 5, 10 p., e0713.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  26 Downloads (Pure)

• Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine

  O'Connell, C. L., Baer, M. R., Ørskov, A. D., Saini, S. K., Duong, V. H., Kropf, P., Hansen, J. W., Tsao-Wei, D., Jang, H. S., Emadi, A., Holmberg-Thyden, S., Cowland, J., Brinker, B. T., Horwood, K., Burgos, R., Hostetter, G., Youngblood, B. A., Hadrup, S. R., Issa, J. P., Jones, P. & 3 others, Baylin, S. B., Siddiqi, I. & Grønbaek, K., 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 24, p. 5306-5316 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

  8 Downloads (Pure)
• 2021

  Mutations known from B-cell lymphoid malignancies are not found in CD34⁺ stem cells from patients with lymphoma

  Husby, S., Favero, F., Rodriguez-Gonzalez, F. G., Sutton, L. A., Haastrup, E. K., Ørskov, A. D., Hansen, J. W., Arboe, B., Aslan, D., Clasen-Linde, E., Rahbek Gjerdrum, L. M., Gørlev, J. S., Brown, P., Fischer-Nielsen, A., Rosenquist, R., Weischenfeldt, J. & Grønbæk, K., 2021, In: Leukemia and Lymphoma. 62, 11, p. 2808-2811

  Research output: Contribution to journal › Journal article › Research › peer-review
  2 Citations (Scopus)
• 2020

  Activation of a subset of evolutionarily young transposable elements and innate immunity are linked to clinical responses to 5-azacytidine

  Ohtani, H., Ørskov, A. D., Helbo, A. S., Gillberg, L., Liu, M., Zhou, W., Ungerstedt, J., Hellström-Lindberg, E., Sun, W., Liang, G., Jones, P. A. & Grønbæk, K., 2020, In: Cancer Research. 80, 12, p. 2441-2450 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  32 Citations (Scopus)

• Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

  Saini, S. K., Ørskov, A. D., Bjerregaard, A. M., Unnikrishnan, A., Holmberg-Thydén, S., Borch, A., Jensen, K. V., Anande, G., Bentzen, A. K., Marquard, A. M., Tamhane, T., Treppendahl, M. B., Gang, A. O., Dufva, I. H., Szallasi, Z., Ternette, N., Pedersen, A. G., Eklund, A. C., Pimanda, J., Grønbæk, K. & 1 others, Hadrup, S. R., 2020, In: Nature Communications. 11, 1, 5660.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  54 Citations (Scopus)

  55 Downloads (Pure)

• Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers with low mutational burden

  Saini, S. K., Orskov, A., Bjerregaard, A-M., Unnikrishnam, A., Holmberg-Thyden, S., Borch, A., Anande, G., Bentzen, A., Marquard, A., Tamhane, T., Gang, A., Defva, I., Szallasi, Z., Eklund, A., Pimanda, J., Gronbaek, K. & Hadrup, S., 1 May 2020, In: Journal of Immunology. 204, 1 supplement, 2 p., 242.14.

  Research output: Contribution to journal › Conference abstract in journal › Research
• 2019

  Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

  Gillberg, L., Ørskov, A. D., Nasif, A., Ohtani, H., Madaj, Z., Hansen, J. W., Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, J., Hajkova, P., Jones, P. A. & Grønbæk, K., 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  49 Citations (Scopus)

  38 Downloads (Pure)
• 2018

  Vitamin C - A new player in regulation of the cancer epigenome

  Gillberg, L., Ørskov, A. D., Liu, M., Harsløf, L. B. S., Jones, P. A. & Grønbæk, K., Aug 2018, In: Seminars in Cancer Biology. 51, p. 59-67

  Research output: Contribution to journal › Review › Research › peer-review
  76 Citations (Scopus)
• 2017

  Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

  Hansen, J. W., Sandholdt, H., Siersma, V., Ørskov, A. D., Holmberg, S., Bjerrum, O. W., Hasselbalch, H. C., Olivarius, N. D. F., Grønbæk, K. & Andersen, C. L., Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review
  5 Citations (Scopus)

• DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

  Ørskov, A. D. & Grønbæk, K., Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.

  Research output: Contribution to journal › Review › Research › peer-review
  6 Citations (Scopus)
• 2016

  Immune Mechanisms in Myelodysplastic Syndrome

  Glenthøj, A., Ørskov, A. D., Hansen, J. W., Hadrup, S. R., O'Connell, C. & Grønbæk, K., 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access
  54 Citations (Scopus)

• Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

  Hansen, J. W., Westman, M. K., Sjö, L. D., Saft, L., Sommer Kristensen, L., Ørskov, A. D., Treppendahl, M., Andersen, M. K. & Grønbaek, K., Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  35 Citations (Scopus)

• Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine

  Liu, M., Ohtani, H., Zhou, W., Ørskov, A. D., Charlet, J., Zhang, Y. W., Shen, H-R., Baylin, S. B., Liang, G., Grønbæk, K. & Jones, P. A., 13 Sep 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 37, 7 p., 10238-44.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  156 Citations (Scopus)
• 2015

  Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

  Ørskov, A. D., Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, K., 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  160 Citations (Scopus)