I have two major focus areas in my research and clinical work.

The first focus on the pathophysiology of metabolic diseases such as liver diseases. I am in particular interested in how our gastrointestinal tract regulates metabolism and how impaired inter-organ communication (the liver-alpha cell axis) contribute to development of comorbidities such as diabetes. To capture these dysmetabolic conditions I have developed and evaluate biochemical based measurement technologies that have enabled my research group to pinpoint disturbances and common pathways in diabetes and fatty liver disease.

The second focus on using state of the art mass-spectrometry based proteomics to study human disease and to explore the clinical applicability of such technology. I am currently the team leader of a visionary effort that bridges forefront technology from NNF Center of Protein Research to Denmark most specialized hospital, Rigshospitalet. Here, we together with several departments and clinicians utilizes this advanced technology to evaluate its clinical potential application for diagnostic, prognostics and disease monitoring.

PUBLICATIONS

127 scientific papers: 102 original and 25 reviews in international peer-reviewed journals. 34 first authorship or shared co-first authorship. 18 corresponding/last authorships. Bibliometric Index: H-index 33, i10-index 72. ~3300 citations since 2014 (Web of Science). ORCID: https://orcid.org/0000-0003-4230-5753  

AWARDS

2014: Krogsgaard mindelegat (University of Copenhagen); 2014: Albert Renold Fellowship (EFSD) from the European Foundation for the Study of Diabetes; 2014: European Molecular Biology Organization Fellowship Award; 2015: Invited member of the Harvard Alumni & Harvard Medical School Alumni by Associate Dean, Global Education MBBS, FRCP (UK), MBA Ajay K. Singh, ([email protected]); 2015: Eliteforsk Fellowship (200.000 DKK); 2016: Talent price from the Lundbeck Foundation (100.000DKK); 2017: Elected overseas member of the Royal Society of Medicine, UK.; 2019: Boserup Price (100.000DKK; 2020: Bagger-Sørensens Talent price in Diabetes Research; 2020: Elected Fellow of ‘Det Unge Akademi’ at The Royal Danish Academy of Sciences and Letters; 2020: Astrup Price (Nordic Biochemistry). 2021: EFSD Future Leader Award (5 millionDKK); 2021: Diabetes Foreningen Forskningslegat (Danish Society of Diabetes, yearly scientific award) (100,000DKK); 2021: Danish Diabetes Academy Young Investigator Award (25.000DKK)

EDITORIAL BOARDS and PEER-REVIEW

Guest Editor at Journal of Clinical Medicine (IF:5.6). Review Editor at Frontiers in Endocrinology (IF:3.5) and at Molecules (IF: 4.1) and Associate Editor at BBMJS (Impact factor 1.6). Peer-reviewed >100 articles from various journals including Cell Reports, Cell Metabolism, Diabetes, Diabetes, Obesity and Metabolism, Nature Communications.

LEADERSHIP, SUPERVISING, AND TEACHING ACTIVITIES

Organizer of two international symposia (2021: ‘Insight in Diabetes’, and 2016: ‘Measurement of Hormones’) and several nationals workshops/seminars (latest a nationwide speaker series in diagnostic medicine hosted by the Danish Society for Laboratory Medicine)

Instructor for three massive online open courses with more than 90,000 students listed (https://www.coursera.org/learn/diabetes).

Course Instructor in PhD course ‘Introduction to Omics for Clinical Researchers’ at SUND, KU.

Current primary or co-supervisor for 15 students at University of Copenhagen. Former supervisor for more than 12 students. > 350 class hours at UCPH (Endocrinology, Human Biology, Energy Expenditure). University Pedagogy Course (1-year program) and Responsible Conduct Course for Investigators (UCPH). Mentor for medical students appointed by the Municipality of Copenhagen. Teacher at the Elite Master Program in Personalized Medicine (KU, AAU, AU, SDU).

EDUCATION

2008- 9 January 2014: Medical Doctor, University of Copenhagen (Cand. med.) with top grades

21 June 2014- 5 June 2015: Global Clinical Scholar at Harvard Medical School, Cambridge, MA, USA

2014- 28 March 2017: PhD thesis: ‘Measurement of Gastrointestinal Hormones’ supervised by Assoc. prof. Bolette Hartmann, Prof. Jens J. Holst Assoc. prof. Carolyn F. Deacon and Prof. Matthias Mann

ACADEMIC POSITIONS

Sep 2011 – January 2017: Research Fellow and since 2014 Ph.D. student at the JJ Holst and M. Mann Laboratories

2015-ongoing: Guest Researcher of the Professor Ronald Kahn laboratory at the Joslin Diabetes Center, Harvard Medical School, Boston

2017-2019: Post Doc at Clinical Proteomics, NNF Center for Protein Research, University of Copenhagen, Denmark

2017-ongoing: Affiliated Research Member at the Department of Biomedical Sciences (prof. JJ Holst group)

2017-ongoing: Affiliated Research Member of Max-Planck Institute of Biochemistry (Proteomics and Signal Transduction)

May 2019-Sep 2020: Assistant Professor at Clinical Proteomics, NNF Center for Protein Research, University of Copenhagen, Denmark

Oct 2020 – Associate Professor at Clinical Proteomics and Metabolism, NNF Center for Protein Research, University of Copenhagen, Denmark

CLINICAL POSITIONS

2017-2018: Junior Resident, Emergency Room, Herlev Hospital, Denmark & general practitioner (Laura Lundby)

2018-Current: Specialist Registrar, Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark

INVITED ORAL PRESENTATIONS AT INTERNATIONAL CONFERENCES

Invited speaker to several (>20) national and international conferences the last five years.

PUBLIC DISSEMINATION

I am actively communicating both to laymen and professionals’ exemplified including AAAS and EurekAlert, ScienceNews,  Ugeskriftet For Læger(podcast+article), Videnskab.dk, Innovation Origins. Also see https://www.coursera.org/learn/diabetes

GRANTS

Primary recipients of more than 20 grants (~3 million Euro) from private and public funding agencies including Independent Research Fund Denmark, European Research Council and the Novo Nordisk Foundation.

I am principal investigator on the following large grants

A: NNF Excellence Emerging Investigator Grant – Endocrinology and Metabolism (Application No. NNF19OC0055001)

B: EFSD Future Leader Award (NNF21SA0072746) and

C: DFF Sapere Aude (awardee in year 2021) by the Danish Independent Counsil