Personal profile
CV
Education.
University of Copenhagen Medical School, M.D., February 1983.
Doctoral Thesis: Dynamic aspects of the tubuloglomerular feedback mechanism. University of Copenhagen, March 1992.
- Professional Background
Resident, State University Hospital, Copenhangen, Denmark, February 1983 - August 1983. - Post doctoral fellow, University of Copenhagen, Denmark. September 1983 - May 1987.
- Assistant Professor of Physiology, University of Copenhagen, Denmark. May 1987 - April 1992.
- Associate Professor of Physiology and Biophysics, University of Southern California, USA. February 1988 - January 1993.
- Associate Professor of Physiology, University of Copenhagen, Denmark. February 1993 - September 1994.
- Adjunct Associate Professor of Physiology and Biophysics, Brown University, Providence, USA. February 1993 - June 1994.
- Adjunct Professor of Physiology and Biophysics, Brown University, Providence, USA. July 1994 - december 2005.
- Professor of Physiology, University of Copenhagen, Denmark. October 1994 - present.
- Chairman, Department of Medical Physiology, University of Copenhagen, July 2006 - December 2007.
- Head of Department, Department of Biomedical Sciences, January 2007 - 2015.
Society memberships
- Scandinavian Physiological Society
- American Physiological Society
- The Council for High Blood, Pressure Research - the American Heart Association
- The Danish Hypertension Society
- The Mathematical Association of America
- The American Mathematical Society
- The Society for Mathematical Biology
- The Society for Industrial and Applied Mathematics
Administrative work
- Member of the Research Committe of the American Heart Association-Greater Los Angeles Affiliate, 1990-1993.
- Member of the Department Board, the Department of Medical Physiology, University of Copenhagen, fall 1995 - present.
- Member of the Life Science Working Group, The European Space Agency, Paris France, spring 1994 - fall 1998.
- Member of the Research Committee for the School of Medicine, The University of Copenhagen, fall 1995 - present.
- Member of the Steering Committee of the Research Committee for the School of Medicine, The University of Copenhagen, fall 1999 - present.
- Member of the Strategic Planning Committee for the School of Medicine, The University of Copenhagen, Spring 2002 - present.
- Member of the Board for the following foundations: Kaj Bunch-Jensen og Alis Bunch-Jensens Fund, Ruth-Koenig-Petersens Fund, Johan Quentin and wife's Fund (Chairman).
Consultantships
- Member of the Fellowship Study Section, the American Heart Association-Greater Los Angeles Affiliate, 1989-1994
- Member of the Study Section for Kidney and Urology Research Centers, National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Washington D.C., fall 1991.
- Ad hoc reviewer of Nephrology Grants for the Department of Veterans Affairs, Veterans Health Administration, Washington D.C. Spring 1992.
- Special Study Section Member (review of grant applications), National Institutes of Health, Washington, D.C., 1992 - present.
- Member of the International Study Section for Integrative Physiology, ESA/NASA, Washington D.C. Review of grants in connection with the International Space Station, summer 1997, winter 1999, and winter 2000.
- External consultant in connection with the international evaluation of Dutch Biomedical research, The Royal Dutch Academy of Science, Amsterdam, Holland, spring 1998.
- Member of the Study Section (review of grant applications), the Danish Heart Association, 2001 - 2007.
- Member of the Study Section (review of grant applications), the Novo-Nordisk Foundation, 2006 - present
Editorial work
- Invited guest editor on a special issue of Cardiovascular Research on the use of "Chaos theory" in cardiology, 1995-1996.
- Member of the Editorial Board for American Journal of Physiology - Integrative and Regulatory Physiology, 2001- present.
Supervision
Supervisor for 14 completed Ph.D. students (12 at the University of Copenhagen, and 2 at the University of Southern California). Currently supervising 6 Ph.D. students.
Publications
Published 175 peer reviewed papers in international journals, and 18 book chapters.
Patents
Holder of 2 patents.
Primary fields of research
- Renal and Cardiovascular Physiology.
- Regulation of the extracellular volume.
- Hypertension. Regulation of microvascular function.
- Gap junction function in heart and smooth muscle.
- Intercellular signaling. Mathematical Modeling of Physiological Systems.
- Application of the theory of non-linear dynamical systems to physiological problems.
Keywords
- Faculty of Health and Medical Sciences
Collaborations and top research areas from the last five years
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From blood flow to organ function: The physiology of autoregulatory dynamics
Holstein-Rathlou, N. H. & Marsh, D. J., 2026, In: Experimental Physiology. 111, 1Research output: Contribution to journal › Editorial › Research › peer-review
Open AccessFile4 Downloads (Pure) -
Response of the Nephron Arterial Network and Its Interactions to Acute Hypertension: A Simulation
Marsh, D. J. & Holstein-Rathlou, N. H., 2025, In: Function. 6, 2, 15 p., zqae049.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)18 Downloads (Pure) -
Toward a full-scale model of renal hemodynamics using a reconstructed vascular tree
Xu, P., Darkner, S., Sosnovtseva, O. & Holstein-Rathlou, N. H., 2025, In: American Journal of Physiology - Renal Physiology. 328, 5, p. F702-F723Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Downloads (Pure) -
Cardiovascular autonomic nervous function in children conceived by assisted reproductive technology with frozen or fresh embryo transfer
Mizrak, I., Lund, M. A. V., Landgrebe, A. V., Asserhøj, L. L., Holstein-Rathlou, N. H., Greisen, G., Clausen, T. D., Main, K. M., Vejlstrup, N. G., Jensen, R. B., Pinborg, A. & Madsen, P. L., 2024, In: American journal of physiology. Heart and circulatory physiology. 326, 1, p. H216-H222 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)19 Downloads (Pure) -
Ephaptic coupling enables action potential conduction
Waaben, J., Hofgaard, J. P., Pick, G.-L., Loisel, C., Engstrøm, T., von Holstein-Rathlou, N.-H., Poelzing, S. & Nielsen, M. S., 2024, bioRxiv, 18 p. (bioRxiv).Research output: Working paper › Preprint
Open AccessFile6 Downloads (Pure) -
The renal vasodilatation from β-adrenergic activation in vivo in rats is not driven by KV7 and BKCa channels.
Sorensen, C. M., Salomonsson, M., Lubberding, A. F. & Holstein-Rathlou, N.-H., 9 Mar 2024, In: Experimental Physiology. 109, 6, p. 791-803Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile41 Downloads (Pure) -
A hybrid approach to full-scale reconstruction of renal arterial network
Xu, P., Holstein-Rathlou, N.-H., Søgaard, S. B., Gundlach, C., Sørensen, C. M., Erleben, K., Sosnovtseva, O. & Darkner, S., 9 May 2023, In: Scientific Reports. 13, 1, 15 p., 7569.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)111 Downloads (Pure) -
Dynamic changes in renal sodium handling during sympathetic stimulation in healthy human males
Petersen, J. C. G., Jonassen, T. E. N., Holstein-Rathlou, N.-H., Petersen, L. G. & Sorensen, C. M., 2023, In: Autonomic Neuroscience: Basic and Clinical. 250, 11 p., 103131.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus)