Research output per year
Research output per year
medical doctor, phD, Dr.med.
Blegdamsvej 3B, 2200 København N, 24 Bygning 24, 24-1-10
Blegdamsvej 3B
2200 København N
Research activity per year
Bacterial evolution during persistence in biofilms with special focus on the development of antibiotic resistance as well as new anti-biofilm treatment strategies such as combination of antibiotics with bacteriophages or hyperbaric oxygen treatment.
Curriculum vitae
PERSONAL INFORMATION
Family name, First name: Ciofu, Oana
Researcher unique identifier(s) ORCID https://orcid.org/0000-0001-5648-4858
Date of birth: 03/07/1967
Nationality: Danish
My research focuses on bacterial evolution and adaptation in biofilms, with special interest in development of antibiotic resistance with the aim of optimizing the treatment and improving the outcome of patients with chronic infections including the potential use of viruses (bacteriophages) to control pathogenic biofilms.
Total number of peer-reviewed publications: 104 and 14 book chapters
Number of first authorships: 21
Number of corresponding authorships: 32
Number of citations: 9499
H-index: 45 Web of Science
Ciofu, O. - Search Results - PubMed (nih.gov)
The Family Hede Nielsen Award, 2005 for “Research in prevention of development of antibiotic resistance by use of antioxidants”, 400.000 DKK
Supervisor of 8 PhD students; 15 master projects for students with biological educations; more than 30 bachelor and master projects of medical students;
External examiner for Bachelor of Science (BSc) and Master of Science (MSc) in Engineering programmes and master programmes the field of Civil - Kemi. : appointed by the Danish Agency for Higher Education since 2012 til 2026
ISIM Department supervisor for assistant professors and post docs participating in the Teacher Course for Teaching and Learning in Higher Education (Adjunktpædagogikum).
Grant application review
The National Authority for Scientific Research of the Romanian Government, French Research Council, Flemish Research Council, Finish Research Council, Austrian Research Council, Estonian Research Council, German Cystic Fibrosis Foundation, Irish Research Council, Estonian Research Council, Italian Cystic Fibrosis Foundation, United Kingdom CF Trust, ESCMID Research grants evaluator, EU Research Council
Associate editor Frontiers in Cellular and Infection Microbiology;
Reviewer for following scientific journals
Reviewer for several scientific journals: Antimicrobial Agents and Chemotherapy, Applied and Environmental Microbiology, Microbiology, Microbiology Open, Microbiological Research, mBio, npj Biofilms and Microbiomes, Microbiology Spectrum, BMC Infectious Diseases, BMC Pulmonary Medicine, Scientific report ( Nature), ISME Journal, Journal of Cystic Fibrosis, Journal of Antimicrobial Chemotherapy, Journal of Global Antimicrobial Resistance, Frontiers Microbiology, FEMS Microbiology Reviews, FEMS Microbiology Letters, Protein Engineering, Design and Selection, Biomedicine and Pharmacotherapy, Applied Microbiology and Biotechnology, European Respiratory Journal, Expert Review of Anti-infective Therapy, Computational and Structural Biotechnology Journal, APMIS.
Ass. prof. Research Laboratory Leader Laia Fernández Barat, University of Barcelona, Spain Topic: treatment of biofilm infection
Ass. prof. Coen van Hasselt, University of Leiden, the Netherlands. Topic: modelling of antimicrobial resistance development
Dr.rer. nat. Oliwia Makarewicz , Bereichsleiterin Laborforschung, Institut für Infektionsmedizin und Krankenhaushygiene, Jena, Germany. Topic: phage treatment of Pseudomonas aeruginosa biofilms
Organizer of Cultural Night ISIM event October 2022
Course leader and teacher in the “Medical Microbiology” course as part of bachelor education of medical students
Coordinator of the first interdisciplinary One Health course at the Faculty of Health and medical Sciences “Antimicrobial resistance: a threat for humans and animals health”where medical and veterinary students are working together in mixed groups around specific infectious diseases cases.
Supervisor phD students: 6, several master and bachelor students
I am primarily interested in the cure of persistent, chronic infections due to bacterial biofilms and my goal is to improve the treatment of this type of infections by interfering with the bacterial evolution and by enhancing the activity of antibiotics in biofilms.
I have no possible conflicts of interest.
Evolution of antibiotic resistance in biofilms vs planktonic cultures under treatment with sub-inhibitory concentrations of antibiotics
The role of oxidative stress in bacterial evolution in biofilms
The interaction between bacteriophages and P.aeruginosa biofilms in the presence and absence of antibiotics.
The effect of the new combination of ceftazidime-avibactam on P. aeruginosa biofilms.
The development of resistance to azithromycin in P. aeruginosa biofilms.
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review
Research output: Contribution to journal › Review › Research › peer-review
Research output: Contribution to journal › Journal article › Research › peer-review