Personal profile
Short presentation
Research focuses on the role of circulating extracellular vesicles in health and disease and their potential as a source for future disease biomarkers
Keywords
- Faculty of Health and Medical Sciences
- Extracelluar vesicles
- Microparticles
- Exosomes
- Biomarkers
- Autoimmune diseases
- Neurodegenerative diseases
- Plasma proteome
- Proteomics
- High resolution mass spectrometry
Collaborations and top research areas from the last five years
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Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer
Guzman, U. H., Rykar, M., Hendriks, I. A., Stewart, H., Denisov, E., Hagedorn, B., Petzoldt, J., Kreutzmann, A., Mueller, Y., Arrey, T. N., Colonius, I., Østergaard, O., Koenig, C., Kraegenbring, J., Fort, K. L., Couzijn, E., Hauschild, J.-P., Hermanson, D., Zabrouskov, V. & Hock, C. & 2 others, , 9 Jan 2026, (E-pub ahead of print) In: Molecular & cellular proteomics : MCP. p. 101504Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of protein biomarker candidates associated with organ-specific immune-related toxicity and response to management by plasma proteomics
Kverneland, A. H., Østergaard, O., Sohlin, J. E., Noringriis, I. M., Jurlander, R. S., Olsen, J. V. & Svane, I. M., 2025, In: BMJ Oncology. 4, 1, 12 p., e000696.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Deep Proteome Analysis of Cerebrospinal Fluid from Pediatric Patients with Central Nervous System Cancer
Mirian, C., Østergaard, O., Thastrup, M., Modvig, S., Foss-Skiftesvik, J., Skjøth-Rasmussen, J., Berntsen, M., Britze, J., Yde Nielsen, A. C., Mathiasen, R., Schmiegelow, K. & Olsen, J. V., 2024, In: Journal of Proteome Research. 23, 11, p. 5107-5121 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)17 Downloads (Pure) -
Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data
Mirian, C., Thastrup, M., Mathiasen, R., Schmiegelow, K., Olsen, J. V. & Østergaard, O., 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.Research output: Contribution to journal › Review › peer-review
Open AccessFile8 Citations (Scopus)57 Downloads (Pure) -
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R. & Ochiya, T. & 31 others, , 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2610 Citations (Scopus)32 Downloads (Pure) -
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes: [Inkl. Correction]
Ye, Z., Sabatier, P., Martin-Gonzalez, J., Eguchi, A., Lechner, M., Østergaard, O., Xie, J., Guo, Y., Schultz, L., Truffer, R., Bekker-Jensen, D. B., Bache, N. & Olsen, J. V., 2024, In: Nature Communications. 15, 1, 10 p., 2474.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile51 Citations (Scopus)41 Downloads (Pure) -
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C. & Makarov, A. & 2 others, , 2024, In: Nature Biotechnology. 42, 12, p. 1855–1866 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile172 Citations (Scopus)23 Downloads (Pure) -
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, A. H., Østergaard, O., Emdal, K. B., Svane, I. M. & Olsen, J. V., 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile26 Citations (Scopus)80 Downloads (Pure)