Research output per year
Research output per year
- 39 results
Search results
-
2024
Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data
Mirian, C., Thastrup, M., Mathiasen, R., Schmiegelow, K., Olsen, J. V. & Østergaard, O., 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile1 Citation (Scopus)15 Downloads (Pure) -
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, , 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile380 Citations (Scopus)7 Downloads (Pure) -
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes: [Inkl. Correction]
Ye, Z., Sabatier, P., Martin-Gonzalez, J., Eguchi, A., Lechner, M., Østergaard, O., Xie, J., Guo, Y., Schultz, L., Truffer, R., Bekker-Jensen, D. B., Bache, N. & Olsen, J. V., 2024, In: Nature Communications. 15, 1, 10 p., 2474.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)14 Downloads (Pure) -
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C., Makarov, A. & 2 others, , 2024, (E-pub ahead of print) In: Nature Biotechnology.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access23 Citations (Scopus) -
2023
Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, A. H., Østergaard, O., Emdal, K. B., Svane, I. M. & Olsen, J. V., 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)46 Downloads (Pure) -
2022
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access9 Citations (Scopus) -
2021
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez-Val, A., Bekker-Jensen, D. B., Steigerwald, S., Koenig, C., Østergaard, O., Mehta, A., Tran, T., Sikorski, K., Torres-Vega, E., Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, L. B., Kjøbsted, R., Krogh, N., Lundby, A., Bekker-Jensen, S., Lund-Johansen, F. & Olsen, J. V., 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile75 Downloads (Pure) -
2020
Mass-Spectrometry Based Proteome Comparison of Extracellular Vesicle Isolation Methods: Comparison of ME-kit, Size-Exclusion Chromatography, and High-Speed Centrifugation
Askeland, A., Borup, A., Østergaard, O., Olsen, J. V., Lund, S. M., Christiansen, G., Kristensen, S. R., Heegaard, N. H. H. & Pedersen, S., 2020, In: Biomedicines. 8, 8, 15 p., 246.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Citations (Scopus)47 Downloads (Pure) -
2018
Generation and Characterization of Cell-Derived Microvesicles from HUVECs
Cherre, S., Granberg, M., Østergaard, O., Heegaard, N. H. H. & Rozlosnik, N., 2018, In: BioNanoScience. 8, p. 140–153 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., Beckham, C. & 31 others, , 2018, In: Journal of Extracellular Vesicles. 7, 1, p. 1-47 1535750.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7159 Citations (Scopus)210 Downloads (Pure) -
2017
A review of studies of the proteomes of circulating microparticles: Key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus
Nielsen, C. T., Østergaard, O., Rasmussen, N. S., Jacobsen, S. & Heegaard, N. H. H., 2017, In: Clinical Proteomics. 14, 24 p., 11.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile24 Citations (Scopus)132 Downloads (Pure) -
Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines
Alsarraf, H., Dedic, E., Bjerrum, M. J., Østergaard, O., Kristensen, M. P., Petersen, J. W. & Jørgensen, R., 2017, In: Virulence. 8, 8, p. 1880-1889 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access13 Citations (Scopus) -
Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus
Østergaard, O., Nielsen, C. T., Tanassi, J. T., Iversen, L. V., Jacobsen, S. & Heegaard, N. H. H., 2017, In: Clinical Proteomics. 14, 13 p., 23.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile22 Citations (Scopus)290 Downloads (Pure) -
Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions
Loke, I., Østergaard, O., Heegaard, N. H. H., Packer, N. H. & Thaysen-Andersen, M., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1507-1527 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
50 Citations (Scopus) -
2016
A Novel Fic (Filamentation Induced by cAMP) Protein from Clostridium difficile Reveals an Inhibitory Motif-independent Adenylylation/AMPylation Mechanism
Dedic, E., Alsarraf, H., Welner, D. H., Østergaard, O., Klychnikov, O. I., Hensbergen, P. J., Corver, J., van Leeuwen, H. C. & Jørgensen, R., 2016, In: The Journal of Biological Chemistry. 291, 25, p. 13286-13300 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation
Østergaard, O., Follmann, F., Olsen, A. W., Heegaard, N. H., Andersen, P. & Rosenkrands, I., 2016, In: Molecular and Cellular Proteomics. 15, 12, p. 3540-3550 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access23 Citations (Scopus) -
2015
Cross-sectional study of soluble selectins, fractions of circulating microparticles and their relationship to lung and skin involvement in systemic sclerosis
Iversen, L. V., Ullman, S., Østergaard, O., Nielsen, C. T., Halberg, P., Karlsmark, T., Heegaard, N. H. H. & Jacobsen, S., 2015, In: BMC Musculoskeletal Disorders. 16, 9 p., 191.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access22 Citations (Scopus) -
Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis
Nielsen, C. T., Østergaard, O., Rekvig, O. P., Sturfelt, G., Jacobsen, S. & Heegaard, N. H. H., 2015, In: Lupus. 24, 11, p. 1150-60Research output: Contribution to journal › Journal article › Research › peer-review
51 Citations (Scopus) -
Impact of microRNA-130a on the neutrophil proteome
Pedersen, C. C., Refsgaard, J. C., Østergaard, O., Jensen, L. J., Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access10 Citations (Scopus) -
Important options available--from start to finish--for translating proteomics results to clinical chemistry
Heegaard, N. H. H., Østergaard, O., Bahl, J. M. C., Overgaard, M., Beck, H. C., Rasmussen, L. M. & Larsen, M. R., 2015, In: Proteomics - Clinical Applications. 9, 1-2, p. 235-252 18 p.Research output: Contribution to journal › Review › Research › peer-review
7 Citations (Scopus) -
2014
Filaggrin is a predominant member of the denaturation-resistant nickel-binding proteome of human epidermis
Ross-Hansen, K., Østergaard, O., Tanassi, J. T., Thyssen, J. P., Johansen, J. D., Menné, T. & Heegaard, N. H. H., Apr 2014, In: The Journal of Investigative Dermatology. 134, 4, p. 1164-1166 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
36 Citations (Scopus) -
Papillon-Lefèvre syndrome patient reveals species-dependent requirements for neutrophil defenses
Sørensen, O. E., Clemmensen, S. N., Dahl, S. L., Østergaard, O., Heegaard, N. H. H., Glenthøj, A., Nielsen, F. C. & Borregaard, N., 2014, In: The Journal of Clinical Investigation. 124, 10, p. 4539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
137 Citations (Scopus) -
Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus
Nielsen, C. T., Lood, C., Østergaard, O., Iversen, L. V., Voss, A., Bengtsson, A., Jacobsen, S. & Heegaard, N. H. H., 2014, In: Lupus Now. 1, p. 1-8 8 p., e000026.Research output: Contribution to journal › Journal article › Research › peer-review
36 Citations (Scopus) -
Protein expression, characterization, crystallization and preliminary X-ray crystallographic analysis of a Fic protein from Clostridium difficile
Welner, D., Dedic, E., van Leeuwen, H. C., Kuijper, E., Bjerrum, M. J., Østergaard, O. & Jørgensen, R., 2014, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 70, p. 827-831 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
File4 Citations (Scopus) -
2013
A heparin-based method for flow cytometric analysis of microparticles directly from platelet-poor plasma in calcium containing buffer
Iversen, L. V., Ostergaard, O., Nielsen, C., Jacobsen, S. & Heegaard, N. H. H., 2013, In: Journal of Immunological Methods. 388, 1-2, p. 49-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
Circulating microparticles and plasma levels of soluble E- and P-selectins in patients with systemic sclerosis
Iversen, L., Østergaard, O., Ullman, S., Nielsen, C. T., Halberg, P., Karlsmark, T., Heegaard, N. H. H. & Jacobsen, S., 2013, In: Scandinavian Journal of Rheumatology. 42, 6, p. 473-482 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
29 Citations (Scopus) -
Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors
Rørvig, S., Østergaard, O., Heegaard, N. H. H. & Borregaard, N., 2013, In: Journal of Leukocyte Biology. 94, 4, p. 711-721 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
142 Citations (Scopus) -
Unique Protein Signature of Circulating Microparticles in Systemic Lupus Erythematosus
Østergaard, O., Nielsen, C., Iversen, L. V., Tanassi, J. T., Knudsen, S., Jacobsen, S. & Heegaard, N. H. H., 2013, In: Arthritis & Rheumatism. 65, 10, p. 2680-2690 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
75 Citations (Scopus) -
2012
Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation
Nielsen, C. T., Østergaard, O., Stener, L., Iversen, L. V., Truedsson, L., Gullstrand, B., Jacobsen, S. & Heegaard, N. H. H., 2012, In: Arthritis & Rheumatism. 64, 4, p. 1227-1236 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
151 Citations (Scopus) -
Quantitative proteome profiling of normal human circulating microparticles
Østergaard, O., Nielsen, C. T., Iversen, L. V., Jacobsen, S., Tanassi, J. T. & Heegaard, N. H. H., 2012, In: Journal of Proteome Research. 11, 4, p. 2154-63 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
59 Citations (Scopus) -
2011
Alpha-1-antitrypsin is produced by human neutrophil granulocytes and their precursors and liberated during granule exocytosis
Clemmensen, S. N., Jacobsen, L. C., Rørvig, S., Askaa, B., Christenson, K., Iversen, M., Jørgensen, M. H., Larsen, M. T., van Deurs, B., Østergaard, O., Heegaard, N. H., Cowland, J. B. & Borregaard, N., 1 Jun 2011, In: European Journal of Haematology. 86, 6, p. 517-30 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
47 Citations (Scopus) -
Distinct features of circulating microparticles and their relationship to clinical manifestations in systemic lupus erythematosus
Nielsen, C. T., Østergaard, O., Johnsen, C., Jacobsen, S. & Heegaard, N. H. H., 2011, In: Arthritis & Rheumatism. 63, 10, p. 3067-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
111 Citations (Scopus) -
2009
Integration of the barley genetic and seed proteome maps for chromosome 1H, 2H, 3H, 5H and 7H
Finnie, C., Bagge, M., Steenholdt, T., Østergaard, O., Bak-Jensen, K. S., Backes, G. M., Jensen, A., Giese, N. H., Larsen, J., Roepstorff, P. & Svensson, B., 2009, In: Functional & Integrative Genomics. 9, 1, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access17 Citations (Scopus) -
2007
Lysine 58-cleaved beta2-microglobulin is not detectable by 2D electrophoresis in ex vivo amyloid fibrils of two patients affected by dialysis-related amyloidosis
Giorgetti, S., Stoppini, M., Tennent, G. A., Relini, A., Marchese, L., Raimondi, S., Monti, M., Marini, S., Østergaard, O., Heegaard, N. H. H., Pucci, P., Esposito, G., Merlini, G. & Bellotti, V., 2007, In: Protein Science. 16, 2, p. 343-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
19 Citations (Scopus) -
Spatio-temporal profiling and degradation of alpha-amylase isozymes during barley seed germination
Bak-Jensen, K. S., Laugesen, S., Østergaard, O., Finnie, C., Roepstorff, P. & Svensson, B., 2007, In: F E B S Journal. 274, 10, p. 2552-2565 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
44 Citations (Scopus) -
2004
Aspects of the barley seed proteome during development and germination
Finnie, C., Maeda, K., Østergaard, O., Bak-Jensen, K. S., Larsen, J. & Svensson, B., 2004, In: Biochemical Society Transactions. 32, Pt3, p. 517-9 3 p.Research output: Contribution to journal › Review › Research › peer-review
62 Citations (Scopus) -
Proteome analysis of barley seeds: Identification of major proteins from two-dimensional gels (pI 4-7)
Østergaard, O., Finnie, C., Laugesen, S., Roepstorff, P. & Svensson, B., 2004, In: Proteomics. 4, 8, p. 2437-2447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
124 Citations (Scopus) -
2003
Identification, cloning and characterization of two thioredoxin h isoforms, HvTrxh1 and HvTrxh2, from the barley seed proteome
Maeda, K., Finnie, C., Østergaard, O. & Svensson, B., 2003, In: European Journal of Biochemistry. 270, 12, p. 2633-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
55 Citations (Scopus) -
2002
Initial proteome analysis of mature barley seeds and malt
Østergaard, O., Melchior, S., Roepstorff, P. & Svensson, B., 2002, In: Proteomics. 2, 6, p. 733-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
94 Citations (Scopus)