Otto Kalliokoski

Search results

• 2025

  Development and evaluation of a climbing test in mice: A novel approach for assessing pain-related behaviour

  Malmberg, M. E., Bro, T., Kalliokoski, O., Abelson, K., Bollen, P. & Hestehave, S., 25 Apr 2025.

  Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

• Refining the adjuvant-induced rat model of monoarthritis by optimizing the induction volume and injection site

  Berke, M. S., Hansen, C. P., Kromann, S., Colding-Jørgensen, P., Kalliokoski, O., Jensen, H. E., Sørensen, D. B., Hau, J., Abelson, K. S. P. & Hestehave, S., 10 Mar 2025, (Submitted) 33 p. (bioRxiv).

  Research output: Working paper › Preprint

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  2 Downloads (Pure)

• The threshold for intracranial self-stimulation does not increase in rats exposed to chronic unpredictable stress – A systematic review and meta-analysis

  Berrio Sanchez, J. P., Wilzopolski, J., Hohlbaum, K. & Kalliokoski, O., 2025, In: Behavioural Brain Research. 484, 11 p., 115483.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Downloads (Pure)
• 2024

  Reliability of sucrose preference testing following short or no food and water deprivation—a Systematic Review and Meta-Analysis of rat models of chronic unpredictable stress

  Berrio, J. P., Hestehave, S. & Kalliokoski, O., 2024, In: Translational Psychiatry. 14, 1, 10 p., 39.

  Research output: Contribution to journal › Review › peer-review

  Open Access

  File
  7 Citations (Scopus)

  14 Downloads (Pure)
• 2023

  An autologous blood-derived patch as a hemostatic agent: evidence from thromboelastography experiments and a porcine liver punch biopsy model

  Eskildsen, M. P. R., Kalliokoski, O., Boennelycke, M., Lundquist, R., Settnes, A. & Loekkegaard, E., 2023, In: Journal of Materials Science: Materials in Medicine. 34, 5, 12 p., 20.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  35 Downloads (Pure)

• A systematic review of the development and application of home cage monitoring in laboratory mice and rats

  Kahnau, P., Mieske, P., Wilzopolski, J., Kalliokoski, O., Mandillo, S., Hölter, S. M., Voikar, V., Amfim, A., Badurek, S., Bartelik, A., Caruso, A., Čater, M., Ey, E., Golini, E., Jaap, A., Hrncic, D., Kiryk, A., Lang, B., Loncarevic-Vasiljkovic, N. & Meziane, H. & 10 others, Radzevičienė, A., Rivalan, M., Scattoni, M. L., Torquet, N., Trifkovic, J., Ulfhake, B., Thöne-Reineke, C., Diederich, K., Lewejohann, L. & Hohlbaum, K., 2023, In: BMC Biology. 21, 1, 23 p., 256.

  Research output: Contribution to journal › Review › peer-review

  Open Access

  File
  13 Citations (Scopus)

  27 Downloads (Pure)

• Effects of Multimodal Therapy, Blinding, and Multi-laboratory Protocol Conduct on the Robustness of the Rat Model of Adjuvant Induced Arthritis

  Seveljevic-Jaran, D., Antolic, M., Ognjenovic, A., Kalliokoski, O., Abelson, K. S. P. & Hau, J., 2023, In: In Vivo. 37, 1, p. 115-123 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  34 Downloads (Pure)

• Fighting Irreproducibility in Preclinical Neuroscience Using a Meta-analytical Approach: The Case of the Chronic Unpredictable Stress Model of Depression

  Berrio Sanchez, J. P., Kalliokoski, O. (Supervisor) & Hau, J. (Supervisor), 2023, University of Copenhagen. 80 p.

  Research output: Book/Report › Ph.D. thesis

  Open Access

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  37 Downloads (Pure)

• Hair glucocorticoids are not a historical marker of stress: Exploring the time-scale of corticosterone incorporation into hairs in a rat model

  Colding-Jørgensen, P., Hestehave, S., Abelson, K. S. P. & Kalliokoski, O., 2023, In: General and Comparative Endocrinology. 341, 11 p., 114335.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  20 Downloads (Pure)

• Rapid ammonia build-up in small individually ventilated mouse cages cannot be overcome by adjusting the amount of bedding

  Eskandarani, M. A., Hau, J. & Kalliokoski, O., 2023, In: Lab Animal. 52, p. 130-135

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  35 Downloads (Pure)

• Rethinking data treatment: The sucrose preference threshold for anhedonia in stress-induced rat models of depression

  Berrio, J. P. & Kalliokoski, O., 2023, In: Journal of Neuroscience Methods. 395, 11 p., 109910.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  26 Downloads (Pure)
• 2022

  Antidepressant Fluoxetine Does Not Appear to Interfere With Key Translational Parameters in the Rat Adjuvant-induced Arthritis Model

  Seveljevic-Jaran, D., Kalliokoski, O., Abelson, K. S. P. & Hau, J., 2022, In: In Vivo. 36, 2, p. 635-642

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  30 Downloads (Pure)

• Autologous blood-derived patches: a new means of preventing postsurgical adhesions

  Eskildsen, M., Kalliokoski, O., Bønnelycke, M., Lundquist, R., Settnes, A. & Løkkegaard, E. C. L., 2022, In: Laboratory Animals. 56, S1, p. 188-188 PE13.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  File

• Autologous Blood-derived Patches Used as Anti-adhesives in a Rat Uterine Horn Damage Model

  Eskildsen, M. P., Kalliokoski, O., Boennelycke, M., Lundquist, R., Settnes, A. & Løkkegaard, E., 2022, In: Journal of Surgical Research. 275, p. 225-234

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  30 Downloads (Pure)

• Effects of buprenorphine on acute pain and inflammation in the adjuvant-induced monoarthritis rat model

  Berke, M. S., Colding-Jørgensen, P., Hestehave, S., Kalliokoski, O., Jensen, H. E., Sørensen, D. B., Hau, J. & Abelson, K. S. P., 2022, In: Heliyon. 8, 11, 9 p., e11554.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  22 Downloads (Pure)

• Effects of buprenorphine on model development in an adjuvant-induced monoarthritis rat model

  Berke, M. S., Fensholdt, L. K. D., Hestehave, S., Kalliokoski, O. & Abelson, K. S. P., Jan 2022, In: PLoS ONE. 17, 1, 21 p., e0260356.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  37 Downloads (Pure)

• Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

  Berke, M. S., Colding-Jørgensen, P., Pedersen, L. G., Hestehave, S., Kalliokoski, O., Jensen, H. E., Sørensen, D. B., Hau, J. & Abelson, K. S., 2022, In: Comparative Medicine. 72, 5, p. 320–329 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  23 Downloads (Pure)

• Empirical study of bias in a rat model of rheumatoid arthritis (RA)

  Seveljevic-Jaran, D., Hau, J. (Supervisor), Abelson, K. (Supervisor) & Kalliokoski, O. (Supervisor), 2022, University of Copenhagen. 91 p.

  Research output: Book/Report › Ph.D. thesis

  Open Access

  File
  15 Downloads (Pure)

• Is sweet consumption under thirst and hunger really a good indicatior or depression?

  Berrio Sanchez, J. P., Kalliokoski, O. & Hestehave, S., 2022, In: Laboratory Animals. 56, S1, p. 25-26 S2A5.4.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  File

• We need to talk about fraudulent animal studies: learnings from a systematic review

  Berrio Sanchez, J. P. & Kalliokoski, O., 2022, In: Laboratory Animals. 56, S1, p. 172-172 PD15.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  File
• 2021

  An exploratory investigation of glucocorticoids, personality and survival rates in wild and rehabilitated hedgehogs (Erinaceus europaeus) in Denmark

  Rasmussen, S. L., Kalliokoski, O., Dabelsteen, T. & Abelson, K., 2021, In: BMC Ecology and Evolution. 21, 16 p., 96.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  44 Downloads (Pure)

• Experimental Design and Statistical Analysis

  Kalliokoski, O., 2021, Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, J. & Shapiro, S. J. (eds.). 4 ed. Boca Ration (FL), USA: CRC Press, p. 69-107 39 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
• 2020

  The Mills Have Ayes: A Fictional Account of Real Fraud

  Kalliokoski, O. & Heathers, J., 26 Sept 2020, 27 p.

  Research output: Other contribution › Communication

  Open Access

  File
  30 Downloads (Pure)
• 2019

  A systematic review of studies utilizing hair glucocorticoids as a measure of stress suggests the marker is more appropriate for quantifying short-term stressors

  Kalliokoski, O., Jellestad, F. K. & Murison, R., 1 Dec 2019, In: Scientific Reports. 9, 1, p. 1-14 14 p., 11997.

  Research output: Contribution to journal › Review › peer-review

  Open Access

  File
  66 Citations (Scopus)

  90 Downloads (Pure)

• Failure to replicate? Exacerbated 8-OH-DPAT-induced hypothermia could not be established in single housed mice when tested as part of a battery of depression tests

  Skriver, H., Kjær, M. R., Sørensen, D. B. & Kalliokoski, O., 2019, In: Scandinavian Journal of Laboratory Animal Science. 45, p. 1-11 11 p., 4.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  43 Downloads (Pure)

• Markers of HPA-axis activity and nucleic acid damage from oxidation after electroconvulsive stimulations in rats

  Jørgensen, A., Breitenstein, K., Kalliokoski, O., Weimann, A., Henriksen, T., Poulsen, H. E., Jørgensen, M. B. & Wörtwein, G., 2019, In: Acta Neuropsychiatrica. 31, 6, p. 287-293 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  41 Downloads (Pure)
• 2018

  Are we overestimating the utility of hair glucocorticoids? A systematic review exploring the empirical evidence supporting hair glucocorticoids as a measure of stress

  Kalliokoski, O., Jellestad, F. K. & Murison, R., 24 Jul 2018, In: bioRxiv. 375667.

  Research output: Contribution to journal › Journal article › Research

  Open Access
• 2017

  A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats

  Jorgensen, A., Kalliokoski, O., Forsberg, K., Breitenstein, K., Weimann, A., Henriksen, T., Hau, J., Wörtwein, G., Poulsen, H. E. & Jorgensen, M. B., Mar 2017, In: Free Radical Biology & Medicine. 104, p. 64-74 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Exploring the antigenic response to multiplexed immunizations in a chicken model of antibody production

  Kousted, T. M., Kalliokoski, O., Christensen, S. K., Winther, J. R. & Hau, J., Mar 2017, In: Heliyon. 3, 3, 19 p., e00267.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  191 Downloads (Pure)
• 2016

  Albumin Is an Overlooked but Highly Relevant Allergen Potentially Affecting Laboratory Animal Professionals

  Kalliokoski, O., Kousted, T. M., Koch, J. & Hau, J., 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 696 1 p., PS70.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Applicability of Commercially Available ELISA Kits for the Quantification of Faecal Immunoreactive Corticosterone Metabolites in Mice

  Abelson, K. S. P., Kalliokoski, O., Teilmann, A. C. & Hau, J., 1 Nov 2016, In: In Vivo. 30, 6, p. 739-744 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  608 Downloads (Pure)

• Carotid Catheterization and Automated Blood Sampling Induce Systemic IL-6 Secretion and Local Tissue Damage and Inflammation in the Heart, Kidneys, Liver and Salivary Glands in NMRI Mice

  Teilmann, A. C., Rozell, B., Kalliokoski, O., Hau, J. & Abelson, K. S. P., 10 Nov 2016, In: P L o S One. 11, 11, p. 1-14 14 p., e0166353.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  377 Downloads (Pure)

• Comparison of Per Diem Rates in Europe and the USA

  Hau, J. & Kalliokoski, O., Sept 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 679-680 2 p., PS1.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• The Effect of Induced Antibodies with Respect to Neutralization, Clearance Rate and Functional Activity in a Rabbit/Infliximab Model

  Henriksen, M. L., Teisner, A., Kjeldsen, J., Kalliokoski, O., Hau, J. & Hansen, S. W. K., Sept 2016, In: In Vivo. 30, 5, p. 557-565 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  1 Citation (Scopus)

• Welfare indicators in laying hens in relation to nest exclusion

  Alm, M., Tauson, R., Holm, L., Wichman, A., Kalliokoski, O. & Wall, H., Jun 2016, In: Poultry Science. 95, 6, p. 1238-1247 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  24 Citations (Scopus)
• 2015

  The distorting effect of varying diets on fecal glucocorticoid measurements as indicators of stress: A cautionary demonstration using laboratory mice

  Kalliokoski, O., Teilmann, A. C., Abelson, K. S. P. & Hau, J., 15 Jan 2015, In: General and Comparative Endocrinology. 211, p. 147-153 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)
• 2014

  Amyloid beta_1–42 and the phoshorylated tau threonine 231 in brains of aged cynomolgus monkeys (Macaca fascicularis)

  Darusman, H. S., Gjedde, A., Sajuthi, D., Schapiro, S., Kalliokoski, O., Kristianingrum, Y. P., Handaryani, E. & Hau, J., Nov 2014, In: Frontiers in Aging Neuroscience. 6, p. 1-7 7 p., 313.

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)

• Delayed response task performance as a function of age in cynomolgus monkeys (Macaca fascicularis)

  Darusman, H. S., Call, J., Sajuthi, D., Schapiro, S. J., Gjedde, A., Kalliokoski, O. & Hau, J., Apr 2014, In: Primates. 55, 2, p. 259-67 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  35 Citations (Scopus)

• Impact of heparin and short term anesthesia on the quantification of cytokines in laboratory mouse plasma

  Teilmann, A. C., Kalliokoski, O., Jacobsen, K. R., Hau, J. & Abelson, K. S. P., 20 May 2014, In: Acta Veterinaria Scandinavica (Online). 56, p. 1-9 9 p., 33.

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)

• Manual versus automated blood sampling: Impact of repeated blood sampling on stress parameters and behavior in male NMRI mice

  Teilmann, A. C., Kalliokoski, O., Sørensen, D. B., Hau, J. & Abelson, K. S. P., Oct 2014, In: Laboratory Animals. 48, 4, p. 278-91 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  35 Citations (Scopus)

• Poor Memory Performance in Aged Cynomolgus Monkeys with Hippocampal Atrophy, Depletion of Amyloid Beta 1-42 and Accumulation of Tau Proteins in Cerebrospinal Fluid

  Darusman, H. S., Pandelaki, J., Mulyadi, R., Sajuthi, D., Putri, I. A., Kalliokoski, O. H., Call, J., Abelson, K. S. P., Schapiro, S., Gjedde, A. & Hau, J., 19 Mar 2014, In: In Vivo. 28, 2, p. 173-84 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• The Lonely Mouse - Single Housing Affects Serotonergic Signaling Integrity Measured by 8-OH-DPAT-Induced Hypothermia in Male Mice

  Kalliokoski, O., Teilmann, A. C., Jacobsen, K. R., Abelson, K. S. P. & Hau, J., 1 Dec 2014, In: P L o S One. 9, 12, p. 1-13 13 p., e111065.

  Research output: Contribution to journal › Journal article › Research › peer-review
  37 Citations (Scopus)

• The Success Rate in a Complicated Spatial Memory Test Is Determined by Age, Sex, Life History and Search Strategies in Cynomolgus Monkeys

  Darusman, H. S., Kalliokoski, O., Sajuthi, D., Schapiro, S., Gjedde, A. & Hau, J., 6 Sept 2014, In: In Vivo. 28, 5, p. 741-50 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  1 Citation (Scopus)
• 2013

  Correlations between serum levels of beta amyloid, cerebrospinal levels of tau and phospho tau, and delayed response tasks in young and aged cynomolgus monkeys (Macaca fascicularis)

  Darusman, H. S., Sajuthi, D., Kalliokoski, O., Jacobsen, K. R., Call, J., Schapiro, S. J., Gjedde, A., Abelson, K. S. P. & Hau, J., Jun 2013, In: Journal of Medical Primatology. 42, 3, p. 137-46 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)

• Effects of buprenorphine and meloxicam analgesia on induced cerebral ischemia in C57BL/6 male mice

  Jacobsen, K. R., Fauerby, N., Raida, Z., Kalliokoski, O., Hau, J., Johansen, F. F. & Abelson, K. S., Apr 2013, In: Comparative Medicine. 63, 2, p. 105-13 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  30 Citations (Scopus)

• Mice Do Not Habituate to Metabolism Cage Housing: A Three Week Study of Male BALB/c Mice

  Kalliokoski, O., Jacobsen, K. R., Darusman, H. S., Henriksen, T., Weimann, A., Poulsen, H. E., Hau, J. & Abelson, K., 7 Mar 2013, In: P L o S One. 8, 3

  Research output: Contribution to journal › Journal article › Research › peer-review
  70 Citations (Scopus)
• 2012

  Acclimatization of mice to different cage types and social groupings with respect to fecal secretion of IgA and corticosterone metabolites

  Bundgaard, C. J., Kalliokoski, O., Abelson, K. S. & Hau, J., 2012, In: In Vivo. 26, 6, p. 883-8 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  23 Citations (Scopus)

• Fecal glucocorticoid response to environmental stressors in green iguanas (Iguana iguana)

  Kalliokoski, O., Timm, J., Ibsen, I., Hau, J., Frederiksen, A.-M. & Bertelsen, M. F., 2012, In: General and Comparative Endocrinology. 177, 1, p. 93-97 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  32 Citations (Scopus)

• Postsurgical food and water consumption, fecal corticosterone metabolites, and behavior assessment as noninvasive measures of pain in vasectomized BALB/c mice

  Jacobsen, K. R., Kalliokoski, O., Teilmann, A. C., Hau, J. & Abelson, K. S., Jan 2012, In: Journal of the American Association for Laboratory Animal Science. 51, 1, p. 69-75 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  26 Citations (Scopus)

• Quantitative effects of diet on fecal corticosterone metabolites in two strains of laboratory mice

  Kalliokoski, O., Jacobsen, K. R., Teilmann, A. C., Hau, J. & Abelson, K., Mar 2012, In: In Vivo. 26, 2, p. 213-221 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  25 Citations (Scopus)