Palle Holmstrup

Search results

• 2024

  Cytokine responses of CD4+ T cells and NKT cells to periodontitis-associated bacteria in individuals with or without periodontitis

  Danielsen, A. K., Massarenti, L., Minculescu, L., Jensen, P. Ø., Hansen, P. R., Holmstrup, P., Damgaard, C. & Nielsen, C. H., 2024, (E-pub ahead of print) In: Journal of Periodontal Research.

  Research output: Contribution to journal › Journal article › Research › peer-review

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• Suitability of machine learning models for prediction of clinically defined Stage III/IV periodontitis from questionnaires and demographic data in Danish cohorts

  Enevold, C., Nielsen, C. H., Christensen, L. B., Kongstad, J., Fiehn, N. E., Hansen, P. R., Holmstrup, P., Havemose-Poulsen, A. & Damgaard, C., 2024, In: Journal of Clinical Periodontology. 51, 12, p. 1561-1573 13 p.

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• 2023

  B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls

  Danielsen, A. K., Damgaard, C., Massarenti, L., Østrup, P., Hansen, P. R., Holmstrup, P. & Nielsen, C. H., 2023, In: Journal of Periodontology. 94, 8, p. 997-1007 11 p.

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  3 Citations (Scopus)

  37 Downloads (Pure)

• Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study

  Wagner, A. K., D'Souza, M., Bang, C. N., Holmstrup, P., Blanche, P., Fiehn, N. E., Gislason, G., Pedersen, C. T., Damgaard, C., Nielsen, C. H. & Hansen, P. R., 2023, In: Journal of Clinical Periodontology. 50, 10, p. 1305-1314 10 p.

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  3 Citations (Scopus)

  30 Downloads (Pure)
• 2022

  Complement component 3 and its activation split-products in saliva associate with periodontitis

  Damgaard, C., Massarenti, L., Danielsen, A. K., Graversen, J. H., Holmstrup, P., Nielsen, C. H. & Palarasah, Y., 2022, In: Journal of Periodontology. 93, 9, p. 1294-1301 8 p.

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  7 Citations (Scopus)

  27 Downloads (Pure)
• 2021

  Circulating antibodies against leukotoxin A as marker of periodontitis grades B and C and oral infection with Aggregatibacter actinomycetemcomitans

  Damgaard, C., Danielsen, A. K., Enevold, C., Reinholdt, J., Holmstrup, P., Nielsen, C. H. & Massarenti, L., 2021, In: Journal of Periodontology. 92, 12, p. 1795-1804 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  7 Citations (Scopus)

• Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatment

  Grande, M. A., Belstrøm, D., Damgaard, C., Holmstrup, P., Thangaraj, S. S., Nielsen, C. H. & Palarasah, Y., 2021, In: Journal of Periodontal Research. 56, 1, p. 27-33 7 p.

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  23 Citations (Scopus)

  48 Downloads (Pure)

• Periodontitis increases risk of viable bacteria in freshly drawn blood donations

  Damgaard, C., Sækmose, S. G., Nilsson, M., Kilian, M., Nielsen, C. H. & Holmstrup, P., 2021, In: Blood Transfusion. 19, 5, p. 376-383

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  11 Citations (Scopus)

  56 Downloads (Pure)

• The impact of oral diseases in cirrhosis on complications and mortality

  Grønkjær, L. L., Holmstrup, P., Jepsen, P. & Vilstrup, H., 2021, In: JGH Open. 5, 2, p. 294-300 7 p.

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  5 Citations (Scopus)

  23 Downloads (Pure)
• 2020

  Salivary concentrations of macrophage activation-related chemokines are influenced by non-surgical periodontal treatment: a 12-week follow-up study

  Grande, M. A., Belstrøm, D., Damgaard, C., Holmstrup, P., Könönen, E., Gursoy, M. & Gursoy, U. K., 2020, In: Journal of Oral Microbiology. 12, 1, 7 p., 1694383.

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  17 Citations (Scopus)

  110 Downloads (Pure)

• Sygdomsrisiko og forebyggelse af sygdomme i mundhulen ved generelle sygdomme

  Pedersen, A. M. L., Holmstrup, P., Larsen, T. & Ellefsen, B., 2020, In: Tandlaegebladet. 124, 12, p. 1116-1124

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  11 Downloads (Pure)

• Transition analysis applied to third molar development in a Danish population

  Arge, S., Wenzel, A., Holmstrup, P., Jensen, N. D., Lynnerup, N. & Boldsen, J. L., 2020, In: Forensic Science International. 308, 9 p., 110145.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)
• 2019

  Æstetik, etik og butik

  Holmstrup, P. & Pallesen, U., 2019, In: Aktuel Nordisk Odontologi. 44, p. 6-19 14 p.

  Research output: Contribution to journal › Journal article › Communication

• Komorbiditet ved parodontitis

  Translated title of the contribution: Comorbidity of periodontitisHolm, N-C. R., Holmstrup, P. & Hansen, P. R., 2019, In: Ugeskrift for Laeger. 181, 13, 4 p., V11180758.

  Research output: Contribution to journal › Journal article › Communication

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• Lewis and AB0 blood group-phenotypes in periodontitis, cardiovascular disease, obesity and stroke

  Enevold, C., Nielsen, C. H., Molbo, D., Lund, R., Bendtzen, K., Fiehn, N-E. & Holmstrup, P., 2019, In: Scientific Reports. 9, 1, 7 p., 6283.

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  8 Citations (Scopus)

  91 Downloads (Pure)

• Porphyromonas gingivalis in saliva associates with chronic and aggressive periodontitis

  Damgaard, C., Danielsen, A. K., Enevold, C., Massarenti, L., Nielsen, C. H., Holmstrup, P. & Belstrøm, D., 2019, In: Journal of Oral Microbiology. 11, 1, p. 1-9 9 p., 1653123.

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  48 Citations (Scopus)

  196 Downloads (Pure)
• 2018

  Impact of Oral Hygiene Discontinuation on Supragingival and Salivary Microbiomes

  Belstrøm, D., Sembler-Møller, M. L., Grande, M. A., Kirkby, N., Cotton, S. L., Paster, B. J., Twetman, S. & Holmstrup, P., 2018, In: JDR Clinical & Translational Research. 3, 1, p. 57-64 8 p.

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  34 Citations (Scopus)

  197 Downloads (Pure)

• Influence of periodontal treatment on subgingival and salivary microbiotas

  Belstrøm, D., Grande, M. A., Sembler-Møller, M. L., Kirkby, N., Cotton, S. L., Paster, B. J. & Holmstrup, P., 2018, In: Journal of Periodontology. 89, 5, p. 531-539

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  78 Citations (Scopus)

  227 Downloads (Pure)

• Ny klassifikation af parodontal sygdom

  Klausen, B. & Holmstrup, P., 2018, In: Tandlaegebladet. 122, 4, p. 2-9 1399.

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• Oral erythroplakia - What is it?

  Holmstrup, P., 2018, In: Oral Diseases. 24, 1-2, p. 138-143 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  30 Citations (Scopus)

• Periodontitis in patients with cirrhosis: a cross-sectional study

  Grønkjær, L. L., Holmstrup, P., Schou, S., Kongstad, J., Jepsen, P. & Vilstrup, H., 2018, In: BMC Oral Health. 18, 1, p. 1-7 22.

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  19 Citations (Scopus)

  139 Downloads (Pure)

• Severe periodontitis and higher cirrhosis mortality

  Gronkjaer, L. L., Holmstrup, P., Schou, S., Jepsen, P. & Vilstrup, H., 2018, In: United European Gastroenterology Journal. 6, 1, p. 73-80

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  18 Citations (Scopus)

• The growing problem of antimicrobial resistance

  Holmstrup, P. & Klausen, B., 2018, In: Oral Diseases. 24, 3, p. 291-295 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• Third molar development in a contemporary Danish 13–25 year old population

  Arge, S. O., Boldsen, J. L., Wenzel, A., Holmstrup, P., Jensen, N. D. & Lynnerup, N., Aug 2018, In: Forensic Science International. 289, p. 12-17

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Unique subgingival microbiota associated with periodontitis in cirrhosis patients

  Jensen, A., Ladegaard Grønkjær, L., Holmstrup, P., Vilstrup, H. & Kilian, M., 2018, In: Scientific Reports. 8, p. 1-16 10718.

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  26 Citations (Scopus)

  111 Downloads (Pure)
• 2017

  Blockade of RAGE in Zucker obese rats with experimental periodontitis

  Grauballe, M. B., Østergaard, J. A., Schou, S., Flyvbjerg, A. & Holmstrup, P., Jan 2017, In: Journal of Periodontal Research. 52, 1, p. 97-106 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

  Køllgaard, T. M. S., Enevold, C., Bendtzen, K., Hansen, P. R., Givskov, M., Holmstrup, P. & Nielsen, C. H., 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.

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  29 Citations (Scopus)

  360 Downloads (Pure)

• Immunoglobulin G antibodies against Porphyromonas gingivalis or Aggregatibacter actinomycetemcomitans in cardiovascular disease and periodontitis

  Damgaard, C., Reinholdt, J., Enevold, C., Fiehn, N-E., Nielsen, C. H. & Holmstrup, P., 2017, In: Journal of Oral Microbiology. 9, 1, 1374154.

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  32 Citations (Scopus)

  200 Downloads (Pure)

• Impact of Periodontitis Case Criteria: A Cross-Sectional Study of Lifestyle

  Kongstad, J., Enevold, C., Christensen, L. B., Fiehn, N-E. & Holmstrup, P., Jun 2017, In: Journal of Periodontology. 88, 6, p. 602-609 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  21 Citations (Scopus)

• In vitro complement activation, adherence to red blood cells and induction of mononuclear cell cytokine production by four strains of Aggregatibacter actinomycetemcomitans with different fimbriation and expression of leukotoxin

  Damgaard, C., Reinholdt, J., Palarasah, Y., Enevold, C., Nielsen, C., Brimnes, M. K., Holmstrup, P. & Nielsen, C. H., 2017, In: Journal of Periodontal Research. 52, 3, p. 485-496 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Ligature-associated bacterial profiles are linked to type 2 diabetes mellitus in a rat model and influenced by antibody treatment against TNF-α or RAGE

  Grauballe, M. B., Belstrøm, D., Østergaard, J. A., Paster, B. J., Schou, S., Flyvbjerg, A. & Holmstrup, P., Feb 2017, In: Clinical Implant Dentistry and Related Research. 3, 1, p. 25-31 7 p.

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  6 Citations (Scopus)

  150 Downloads (Pure)

• Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

  Belstrøm, D., Constancias, F., Liu, Y., Yang, L., Drautz-Moses, D. I., Schuster, S. C., Kohli, G. S., Jakobsen, T. H., Holmstrup, P. & Givskov, M., 2017, In: npj Biofilms and Microbiomes. 3, 8 p., 23.

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  90 Citations (Scopus)

  207 Downloads (Pure)

• Microbial profile comparisons of saliva, pooled and site-specific subgingival samples in periodontitis patients

  Belstrøm, D., Sembler-Møller, M. L., Grande, M. A., Kirkby, N., Cotton, S. L., Paster, B. J. & Holmstrup, P., 2017, In: PLOS ONE. 12, 8, 11 p., e0182992.

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  66 Citations (Scopus)

  301 Downloads (Pure)

• Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1

  Damgaard, C., Kantarci, A., Holmstrup, P., Hasturk, H., Nielsen, C. H. & Van Dyke, T. E., 2017, In: Journal of Periodontal Research. 52, 2, p. 246-254 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  37 Citations (Scopus)

• Salivary cytokine levels in early gingival inflammation

  Belstrøm, D., Damgaard, C., Könönen, E., Gürsoy, M., Holmstrup, P. & Gürsoy, U. K., 2017, In: Journal of Oral Microbiology. 9, 1, 7 p., 1364101.

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  30 Citations (Scopus)

  320 Downloads (Pure)

• Salivary microbiota in individuals with different levels of caries experience

  Belstrøm, D., Holmstrup, P., Fiehn, N-E., Kirkby, N., Kokaras, A., Paster, B. J. & Jensen, A. B., 2017, In: Journal of Oral Microbiology. 9, 1, 1270614.

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  40 Citations (Scopus)

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• 2016

  Bacterial composition in whole saliva from patients with severe hyposalivation: a case-control study

  Belstrøm, D., Holmstrup, P., Fiehn, N-E., Rosing, K., Jensen, A. B., Paster, B. J. & Lynge Pedersen, A. M., 2016, In: Oral Diseases. 22, 4, p. 330-337 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  30 Citations (Scopus)

• Comparative analysis of bacterial profiles in unstimulated and stimulated saliva samples

  Belstrøm, D., Holmstrup, P., Jensen, A. B., Kokaras, A., Fiehn, N-E. & Paster, B. J., 2016, In: Journal of Oral Microbiology. 8, 7 p., 30112.

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  55 Citations (Scopus)

  196 Downloads (Pure)

• Identification of Individuals With Undiagnosed Diabetes and Pre-Diabetes in a Danish Cohort Attending Dental Treatment

  Holm, N-C. R., Belstrøm, D., Østergaard, J. A., Schou, S., Holmstrup, P. & Bay Grauballe, M. C., Apr 2016, In: Journal of Periodontology. 87, 4, p. 395-402 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  52 Citations (Scopus)

• Influence of complement on neutrophil extracellular trap release induced by bacteria

  Palmer, L. J., Damgaard, C., Holmstrup, P. & Nielsen, C. H., Feb 2016, In: Journal of Periodontal Research. 51, 1, p. 70-76 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  59 Citations (Scopus)

• Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls

  Belstrøm, D., Jersie-Christensen, R. R., Lyon, D., Damgaard, C., Jensen, L. J., Holmstrup, P. & Olsen, J. V., 2016, In: PeerJ. 4, 17 p., e2433.

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  61 Citations (Scopus)

  427 Downloads (Pure)

• Oral leukoplakia: To treat or not to treat

  Holmstrup, P. & Dabelsteen, E., 20 Jan 2016, In: Oral Diseases. 22, 6, p. 494-497 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  49 Citations (Scopus)

• Presence and consequence of tooth periapical radiolucency in patients with cirrhosis

  Grønkjær, L. L., Holmstrup, P., Schou, S., Schwartz, K., Kongstad, J., Jepsen, P. & Vilstrup, H., 2016, In: Hepatic Medicine: Evidence and Research. 8, p. 97-103 7 p.

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  212 Downloads (Pure)

• Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction

  Hansen, G. M., Belstrøm, D., Nilsson, C. M. P., Helqvist, S., Nielsen, C. H., Holmstrup, P., Tolker-Nielsen, T., Givskov, M. & Hansen, P. R., 2016, In: P L o S One. 11, 12, 13 p., e0168771.

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  13 Citations (Scopus)

  175 Downloads (Pure)

• Relation of Periodontitis to Risk of Cardiovascular and All-Cause Mortality (from a Danish Nationwide Cohort Study)

  Hansen, G. M., Egeberg, A., Holmstrup, P. & Hansen, P. R., 15 Aug 2016, In: The American Journal of Cardiology. 118, 4, p. 489-993 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  83 Citations (Scopus)

• Salivary bacterial fingerprints of established oral disease revealed by the Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) technique

  Belstrøm, D., Paster, B. J., Fiehn, N-E., Jensen, A. B. & Holmstrup, P., 14 Jan 2016, In: Journal of Oral Microbiology. 8, 7 p., 30170.

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  64 Citations (Scopus)

  237 Downloads (Pure)

• Temporal Stability of the Salivary Microbiota in Oral Health

  Belstrøm, D., Holmstrup, P., Jensen, A. B., Kokaras, A., Fiehn, N-E. & Paster, B. J., 2016, In: PLOS ONE. 11, 1, 9 p., 0147472.

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  105 Citations (Scopus)

  169 Downloads (Pure)
• 2015

  Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay

  Hansen, G. M., Nilsson, M., Nielsen, C. H., Holmstrup, P., Helqvist, S., Tolker-Nielsen, T., Givskov, M. & Hansen, P. R., 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0145657.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  4 Citations (Scopus)

• Differentiation of salivary bacterial profiles of subjects with periodontitis and dental caries

  Belstrøm, D., Fiehn, N-E., Nielsen, C. H., Klepac-Ceraj, V., Paster, B. J., Twetman, S. & Holmstrup, P., 2015, In: Journal of Oral Microbiology. 7, p. 1-5 5 p., 27429.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  30 Citations (Scopus)

• Effects of TNF-α blocking on experimental periodontitis and type 2 diabetes in obese diabetic Zucker rats

  Grauballe, M. B., Østergaard, J. A., Schou, S., Flyvbjerg, A. & Holmstrup, P., Sep 2015, In: Journal of Clinical Periodontology. 42, 9, p. 807-16 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  30 Citations (Scopus)