Research output per year
Research output per year
Personal profile
Primary fields of research
My current research is on ocular comorbidity in Atopic Dermatitis with focus on Ocular Surface Diseases and speciel interest in Goblet Cells.
Current research
PhD-project: "Ocular comorbidity in Atopic Dermatitis"
In this project we explore and characterise the eye manifestations to Atopic Dermatitis, here among atopic keratoconjunctivitis (AKC), which is a potential sigh-threatening disease. We aim identify potential risk factors for developing AKC and hope to increase the diagnostic specificity through a broad knowledge of the phenotypic presentation. To reveal some of the pathomechanisms behind, we investigate the conjunctival goblet cells. Hereby, a better understanding of the disease will make it possible for earlier treatment initiation, and thus lower the risk of severe complications with vision loss and blindness.
CV
Employments:
2019-ongoing: Department of Ophthalmology, Copenhagen University Hospital - Rigshospitalet
Academic degrees:
2019-ongoing: PhD Fellow, Eye Translational Research Unit, Department of Drug Design and Pharmacology, University of Copenhagen
2018: MsC in Medicine, University of Southern Denmark
2015: BsC in Medicine, University of Southern Denmark
Funding:
2019-2023: Synoptik-Fonden
2020-2022: Øjenforeningen (Fight for Sight, Denmark)
2020 + 2022: Den lægevidenskabelige del af det Sundhedsvidenskabelige Fakultets fond for videnskabeligt ansatte kandidater og studerende ved Københavns Universitet
2020-2021: Kgl. Hofbuntmager Aage Bangs Fond
2021: Carl og Ellen Hertz' Legat til dansk læge- og naturvidenskab
2021: Gehejmeråd P. Hersleb Classens Rejsestipendium for læger
External positions
Afdeling for Øjensygdomme, Rigshospitalet
Nov 2019 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Comparing the effect of benzalkonium chloride-preserved, polyquad-preserved, and preservative-free prostaglandin analogue eye drops on cultured human conjunctival goblet cells
Hedengran, A., Freiberg, J., May Hansen, P., Boix-Lemonche, G., Utheim, T. P., Dartt, D. A., Petrovski, G., Heegaard, S. & Kolko, M., 2024, In: Journal of Optometry. 17, 1, 7 p., 100481.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)17 Downloads (Pure) -
Higher occurrence of Ocular Surface Disease symptoms in patients with Atopic Dermatitis: data in the FOREVER study
Hansen, P. M., Rovelt, J., Tolstrup, J., Thyssen, J. P., Heegaard, S. & Kolko, M., 2023, In: Investigative Ophthalmology & Visual Science. 64, 8Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Open Access -
Factors associated with ocular surface disease and severity in adults with atopic dermatitis: a nationwide survey
Rønnstad, A., Hansen, P. M., Halling, A. S., Egeberg, A., Kolko, M., Heegaard, S. & Thyssen, J. P., 2022, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 36, 4, p. 592-601Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Downloads (Pure) -
Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties
Hedengran, A., Freiberg, J. C., Hansen, P. M., Jacobsen, J., Larsen, S. W., Harloff‐helleberg, S., Freude, K., Boix‐lemonche, G., Petrovski, G., Heegaard, S. & Kolko, M., 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)34 Downloads (Pure) -
IFNγ reduces viability in human conjunctival goblet cells in vitro
Rævdal, P., Nagstrup, A. H., Thyssen, J. P., Heegaard, S. & Kolko, M., 2022, In: Acta Ophthalmologica. 100, S267Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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IL-4 and IL-13 both contribute to the homeostasis of human conjunctival goblet cells in vitro
Hansen, P. M., Tollenaere, M. A. X., Hedengran, A., Heegaard, S., Amoudruz, P., Røpke, M., Thyssen, J. P., Kolko, M. & Norsgaard, H., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 8, p. 2555-2558Research output: Contribution to journal › Letter › Research › peer-review
Open AccessFile20 Citations (Scopus)25 Downloads (Pure) -
Interleukin (IL)-13 and IL-4 promote proliferation and mRNA expression of MUC2 and MUC5AC in primary human conjunctival goblet cells
Tollenaere, M. A. X., Raevdal, P., Hedengran, A., Heegaard, S., Roepke, M., Schneider, S., Norsgaard, H., Thyssen, J. P. & Kolko, M., 2022, In: British Journal of Dermatology. 186, 4, p. E146-E146 1 p., 620.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Bidirectional association between atopic dermatitis, conjunctivitis, and other ocular surface diseases: A systematic review and meta-analysis
Ravn, N. H., Ahmadzay, Z. F., Christensen, T. A., Larsen, H. H. P., Loft, N., Rævdal, P., Heegaard, S., Kolko, M., Egeberg, A., Silverberg, J. I., Halling, A. S. & Thyssen, J. P., 2021, In: Journal of the American Academy of Dermatology. 85, 2, p. 453-461 9 p.Research output: Contribution to journal › Review › Research › peer-review
24 Citations (Scopus)