Research output per year
Research output per year
Personal profile
CV
Education:
2013 : Ph.D, Structural Biology and NMR Laboratory, the Department of Biology, University of Copenhagen. Ph.D. grant awarded by the Oticon Foundation.
2008 : M.Sc. Chemistry, the Deparment of Chemistry, University of Copenhagen
Ohter positions:
2017- : Post Doc, Team VAR2CSA, ISIM, University of Copenhagen
2015-17: Post Doc, University College London, UK
2014-15 : Post Doc, team VAR2CSA, ISIM, University of Copenhagen
Short presentation
In the VAR2CSA team I am involved in protein production, protein conjugation experiments and development within upstream/downstream processes to optimize production of recombinant malaria protein for use in in vitro and in vivo experiments.
During my education I have worked with proteins, focused on studying their structural and functional relationship and characterising the atomic details of their ligand interaction. The main tool for this has been NMR spectroscopy; however, I have also worked with crystallography, molecular modeling, binding kinetics measured by Attana and isothermal titration calorimetry.
Keywords
- Faculty of Science
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 650 Citations
- 24 Journal article
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Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages
Walker, M. R., Underwood, A., Björnsson, K. H., Raghavan, S. S. R., Bassi, M. R., Binderup, A., Pham, L. V., Ramirez, S., Pinholt, M., Dagil, R., Knudsen, A. S., Idorn, M., Soegaard, M., Wang, K., Ward, A. B., Salanti, A., Bukh, J. & Barfod, L., 2024, In: Communications Biology . 7, 1, 14 p., 1239.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Downloads (Pure) -
Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate
Vidal-Calvo, E. E., Martin-Salazar, A., Choudhary, S., Dagil, R., Raghavan, S. S. R., Duvnjak, L., Nordmaj, M. A., Clausen, T. M., Skafte, A., Oberkofler, J., Wang, K., Agerbæk, M. Ø., Løppke, C., Jørgensen, A. M., Ropac, D., Mujollari, J., Willis, S., Garcias López, A., Miller, R. L., Karlsson, R. T. G. & 21 others, , 2024, In: Nature Communications. 15, 1, 20 p., 7553.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice
Skeltved, N., Nordmaj, M. A. A., Berendtsen, N. T., Dagil, R., Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, T., Choudhary, S., Gogenur, I., Christensen, J. P. P., Theander, T. G. G., Daugaard, M., Salanti, A. & Nielsen, M. A. A., 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)51 Downloads (Pure) -
First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Citations (Scopus)57 Downloads (Pure) -
Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching
Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, , 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile69 Downloads (Pure) -
Malaria biomimetic for tumor targeted drug delivery
Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, T., Dagil, R., Daugaard, M., Choudhary, S., Foged, C., Esko, J. D., Zhang, L., Fang, R. H. & Salanti, A., 2023, In: ACS Nano. 17, 14, p. 13500–13509Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus) -
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, S. S. R., Dagil, R., Lopez-Perez, M., Conrad, J., Bassi, M. R., Quintana, M. D. P., Choudhary, S., Gustavsson, T., Wang, Y., Gourdon, P., Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, C., Nielsen, M. A., Barfod, L., Hviid, L., Salanti, A., Lavstsen, T. & Wang, K., 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)69 Downloads (Pure) -
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
Wang, C. K., Nelepcu, I., Hui, D., Oo, H. Z., Truong, S., Zhao, S., Tahiry, Z., Esfandnia, S., Ghaidi, F., Adomat, H., Dagil, R., Gustavsson, T., Choudhary, S., Salanti, A., Sorensen, P. H., Al Nakouzi, N. & Daugaard, M., 2022, In: Scientific Reports. 12, 3075.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)37 Downloads (Pure)