CURRENT POSITION

PhD fellow - Kiehn & Allodi Laboratories, University of Copenhagen, Denmark

EDUCATION

On-going:   PhD in Neuroscience - University of Copenhagen, Denmark

2016:   MSc in Biomedicine - University of Southern Denmark, Denmark

2014:   BSc in Biochemistry and Biomedical Sciences - Universitat de València, Spain

RESEARCH EXPERIENCE

Mar 2019 - Feb 2020:   Research Assistant - Kiehn Laboratory, University of Copenhagen, Denmark

Feb 2017 - Feb 2019:   Research Assistant - Goldman Laboratory, University of Copenhagen, Denmark

Sep 2015 - Sep 2016:   Master thesis student - Kjems Laboratory, Aarhus University, Denmark

Feb 2015 - Jun 2015:   Intern student - Owens Laboratory, University of Southern Denmark, Denmark

Jun 2014 - Aug 2014:   Intern student - Flames Laboratory, Instituto de Biomedicina de Valencia IBV-CSIC, Spain

EXTERNAL RESEARCH GRANTS

2018:   Louis-Hansen Fonden, 225.000 DKK

TEACHING & SUPERVISION

Teaching assistant:

2022:   "Animal models of disease and behavioral analysis" PhD course, Locomotor assessment practicals - University of Copenhagen, Denmark

2021, 2022:   "Advanced Cell Biology" MSc course, Practical course - University of Copenhagen, Denmark

2020, 2021, 2022:   "Neuroscience I - Cells and circuits" MSc course, Animal models in motor function practical - University of Copenhagen, Denmark

2020:   "Neuronal Signaling" MSc course, Neuroanatomy practical - University of Copenhagen, Denmark

Co-supervision:

2022 (on-going):   Dana Blenda Ahlmark, MSc in Neuroscience - University of Copenhagen, Denmark

2021:   Kevin Weng, BSc in Machine Learning and Computer Science - University of Copenhagen, Denmark

RELEVANT SCIENTIFIC SKILLS

Animal manipulation of rodents (FELASA ABD certificate no. ABD-F032/10/21-8), maintenance of transgenic colonies, handling of ALS and PD models, microsurgery (neonatal and adult), phenotyping and genotyping, behavioural testing and locomotor analysis, non-invasive analysis with IVIS. DNA and RNA handling, spatial transcriptomic techniques including RNAscope in situ hybridization, CARTANA/10X Genomics in situ sequencing, and Nanostring spatial profiling. Primary and stem cell culture, in vitro differentiation of stem cells. Conventional histology. Flow cytometry. Imaging and data analysis, R programming.

I am a PhD fellow in Kiehn and Allodi Laboratories of the Department of Neuroscience, studying spinal interneuron dysfunction in ALS pathophysiology. While the first part of my project uncovered the early loss of inhibitory pre-motor inputs in ALS and its consequences for locomotor phenotype, I am currently focused on describing the temporal dynamics of spinal interneuron dysregulation in the disease from a transcriptomic point of view. For this purpose, I make use of several multiplexing techniques, including RNAscope HiPlexUp in situ hybridization, spatial transcriptomics, and bioinformatic analysis.