Rune Ehrenreich Kuhre

Search results

• 2024

  Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans

  Jacobsen, J. M., Petersen, N., Torz, L., Gerstenberg, M. K., Pedersen, K., Østergaard, S., Wulff, B. S., Andersen, B., Christoffersen, B. O., Reitman, M. L., John, L. M. & Kuhre, R. E., 2024, In: Cell Reports. 43, 8, 18 p., 114501.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)

• Improved leptin sensitivity and increased soluble leptin receptor concentrations may underlie the additive effects of combining PYY [ 1–34] and exendin-4 on body weight lowering in diet-induced obese mice

  Wulff, B. S., Kuhre, R. E., Selvaraj, M., Rehfeld, J. F., Niss, K., Fels, J. J., Anna, S., Raun, K. & Gerstenberg, M. K., 2024, In: Heliyon. 10, 12, 13 p., e32009.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Downloads (Pure)
• 2023

  GDF15 promotes weight loss by enhancing energy expenditure in muscle

  Wang, D., Townsend, L. K., DesOrmeaux, G. J., Frangos, S. M., Batchuluun, B., Dumont, L., Kuhre, R. E., Ahmadi, E., Hu, S., Rebalka, I. A., Gautam, J., Jabile, M. J. T., Pileggi, C. A., Rehal, S., Desjardins, E. M., Tsakiridis, E. E., Lally, J. S. V., Juracic, E. S., Tupling, A. R., Gerstein, H. C. & 9 others, Paré, G., Tsakiridis, T., Harper, M. E., Hawke, T. J., Speakman, J. R., Blondin, D. P., Holloway, G. P., Jørgensen, S. B. & Steinberg, G. R., 2023, In: Nature. 619, 7968, p. 143-150 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  74 Citations (Scopus)

  6 Downloads (Pure)

• Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

  Pedersen, K., Andersen, H., Fledelius, C., Holst, J. J., Hjuler, S. T. & Kuhre, R. E., 2023, In: Molecular Metabolism. 69, 101689.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  10 Downloads (Pure)

• Weight loss by calorie restriction does not alter appetite-regulating gut hormone responses from perfused rat small intestine

  Gerstenberg, M. K., Andersen, D. B., Torz, L., Castorena, C. M., Bookout, A. L., Hartmann, B., Rehfeld, J. F., Petersen, N., Holst, J. J. & Kuhre, R. E., 2023, In: Acta Physiologica. 238, 1, 12 p., e13947.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  26 Downloads (Pure)
• 2022

  Housing-temperature reveals energy intake counter-balances energy expenditure in normal-weight, but not diet-induced obese, male mice

  John, L. M., Petersen, N., Gerstenberg, M. K., Torz, L., Pedersen, K., Christoffersen, B. Ø. & Kuhre, R. E., 2022, In: Communications Biology . 5, 1, 13 p., 946.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  14 Downloads (Pure)

• Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

  Grunddal, K. V., Trammell, S. A. J., Bæch-Laursen, C., Andersen, D. B., Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, I., Tyrberg, B., Li, C., Rosenkilde, M. M., Hartmann, B., Holst, J. J. & Kuhre, R. E., 2022, In: Diabetologia. 65, p. 1018–1031

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  38 Downloads (Pure)
• 2021

  Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans

  Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, R. E., Holst, J. J., Rehfeld, J. F. & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

  Modvig, I. M., Kuhre, R. E., Jepsen, S. L., Xu, S., Engelstoft, M. S., Egerod, K. L., Schwartz, T. W., Ørskov, C., Rosenkilde, M. M. & Holst, J. J., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  33 Citations (Scopus)

  30 Downloads (Pure)

• Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

  Jonsson, I., Bojsen-Moller, K. N., Kristiansen, V. B., Veedfald, S., Albrechtsen, N. J. W., Clausen, T. R., Kuhre, R. E., Rehfeld, J. F., Holst, J. J., Madsbad, S. & Svane, M. S., 2021, In: Frontiers in Endocrinology. 12, 11 p., 681116.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)

  44 Downloads (Pure)

• L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion

  Kuhre, R. E., Modvig, I. M., Jepsen, S. L., Kizilkaya, H. S., Bæch-Laursen, C., Smith, C. A., Reimann, F., Gribble, F. M., Rosenkilde, M. M. & Holst, J. J., 2021, In: Frontiers in Endocrinology. 12, 12 p., 690387.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  41 Downloads (Pure)

• Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

  Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, C. Z., Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, J. J., Wewer Albrechtsen, N. J., Madsbad, S. & Kuhre, R. E., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  10 Citations (Scopus)

• Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

  Andersen, D. B., Grunddal, K. V., Pedersen, J., Kuhre, R. E., Lund, M. L., Holst, J. J. & Ørskov, C., 2021, In: Endocrinology. 162, 3, bqaa246.

  Research output: Contribution to journal › Journal article › Research › peer-review
  36 Citations (Scopus)
• 2020

  An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

  Madsen, T. D., Hansen, L. H., Hintze, J., Ye, Z., Jebari, S., Andersen, D. B., Joshi, H. J., Ju, T., Goetze, J. P., Martin, C., Rosenkilde, M. M., Holst, J. J., Kuhre, R. E., Goth, C. K., Vakhrushev, S. Y. & Schjoldager, K. T., 2020, In: Nature Communications. 11, 1, 13 p., 4033.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  52 Citations (Scopus)

  134 Downloads (Pure)

• Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

  Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, R. E., Albrechtsen, N. J. W., Hansen, S. H., Trammell, S. A. J., Svenningsen, J. S., Rehfeld, J. F., Bojsen-Møller, K. N., Jørgensen, N. B., Holst, J. J., Madsbad, S., Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1

  Jepsen, S. L., Vestergaard, E. T., Larraufie, P., Gribble, F. M., Reimann, F., Jorgensen, J. O. L., Holst, J. J. & Kuhre, R. E., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 1, p. 266-275

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  9 Citations (Scopus)

• Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

  Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, H. C., Eriksen, P. L., Vilstrup, H., Gluud, L. L., Holst, J. J. & Wewer Albrechtsen, N. J., 2020, In: Molecular Metabolism. 42, 18 p., 101080.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  81 Citations (Scopus)

  167 Downloads (Pure)

• Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5

  Trammell, S. A. J., Svenningsen, J. S., Holst, J. J., Gillum, M. P. & Kuhre, R. E., 2020, In: Molecules. 25, 14 p., 2371.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  75 Downloads (Pure)

• In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion

  Xu, S. F. S., Andersen, D. B., Izarzugaza, J. M. G., Kuhre, R. E. & Holst, J. J., 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.

  Research output: Contribution to journal › Journal article › Research › peer-review
  31 Citations (Scopus)

• Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery

  Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, B., Albrechtsen, N. J. W., Kuhre, R. E., Kristiansen, V. B., Rehfeld, J. F., Clausen, T. R., Holst, J. J. & Madsbad, S., 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  29 Citations (Scopus)

• Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

  Modvig, I. M., Andersen, D. B., Grunddal, K. V., Kuhre, R. E., Martinussen, C., Christiansen, C. B., Orskov, C., Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, B., Bojsen-Moller, K. N., Madsbad, S., Albrechtsen, N. J. W. & Holst, J. J., 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  30 Citations (Scopus)

  29 Downloads (Pure)
• 2019

  Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine

  Booz, V., Christiansen, C. B., Kuhre, R. E., Saltiel, M. Y., Sociali, G., Schaltenberg, N., Fischer, A. W., Heeren, J., Zocchi, E., Holst, J. J. & Bruzzone, S., 2019, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 35, 8 p., e3102.

  Research output: Contribution to journal › Journal article › Research › peer-review
  9 Citations (Scopus)

• Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients

  Vestergaard, E. T., Hjelholt, A. J., Kuhre, R. E., Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, J. J. & Jørgensen, J. O. L., 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2581-2592

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  6 Citations (Scopus)

  76 Downloads (Pure)

• Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

  Christiansen, C. B., Trammell, S. A. J., Albrechtsen, N. J. W., Schoonjans, K., Albrechtsen, R., Gillum, M. P., Kuhre, R. E. & Holst, J. J., 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  47 Citations (Scopus)

  266 Downloads (Pure)

• Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

  Kuhre, R. E. & Holst, J. J., 2019, In: Journal of Visualized Experiments. 144, e58533.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  13 Citations (Scopus)

  1 Downloads (Pure)

• Neuromedin U Does Not Act as a Decretin in Rats

  Kuhre, R. E., Christiansen, C. B., Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, I. M., Mandrup-Poulsen, T., Albrechtsen, R., Rosenkilde, M. M., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  9 Citations (Scopus)

  153 Downloads (Pure)

• No direct effect of SGLT2 activity on glucagon secretion

  Kuhre, R. E., Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, N. J. W., Andersen, D. B., Aivazidis, A., Chen, L., Mandrup-Poulsen, T., Ørskov, C., Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, J. J., 2019, In: Diabetologia. 62, 6, p. 1011-1023

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  64 Citations (Scopus)

  139 Downloads (Pure)

• Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors

  Modvig, I. M., Kuhre, R. E. & Holst, J. J., Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  42 Citations (Scopus)

  127 Downloads (Pure)
• 2018

  Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

  Christiansen, C. B., Lind, S. J., Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, R. E., Hartmann, B., Mandrup-Poulsen, T., Deacon, C. F., Albrechtsen, N. J. W. & Holst, J. J., 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  138 Downloads (Pure)

• Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

  Kuhre, R. E., Albrechtsen, N. J. W., Larsen, O., Jepsen, S. L., Balk-Møller, E., Andersen, D. B., Deacon, C. F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, R., Hartmann, B., Rosenkilde, M. & Holst, J. J., 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  157 Citations (Scopus)

  257 Downloads (Pure)
• 2017

  A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

  Wewer Albrechtsen, N. J., Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, R. E., Asmar, M., Veedfald, S., Plamboeck, A., Knop, F. K., Vilsbøll, T., Madsbad, S., Nauck, M. A., Deacon, C. F., Bülow, J., Holst, J. J. & Hartmann, B., 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

  Research output: Contribution to journal › Journal article › Research › peer-review
  13 Citations (Scopus)

• Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

  Nielsen, S., Svane, M. S., Kuhre, R. E., Clausen, T. R., Kristiansen, V. B., Rehfeld, J. F., Holst, J. J., Madsbad, S. & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  36 Citations (Scopus)

  162 Downloads (Pure)

• Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

  Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  363 Downloads (Pure)

• On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat

  Kuhre, R. E., Christiansen, C. B., Saltiel, M. Y., Albrechtsen, N. J. W. & Holst, J. J., 3 Dec 2017, In: Physiological Reports. 5, 23, 13 p., e13507.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  34 Citations (Scopus)

  195 Downloads (Pure)

• Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion

  Saltiel, M. Y., Kuhre, R. E., Christiansen, C. B., Eliasen, R., Conde-Frieboes, K. W., Rosenkilde, M. M. & Holst, J. J., 2017, In: Nutrients. 9, 4, 15 p., 418.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  29 Citations (Scopus)

  191 Downloads (Pure)

• Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

  Windeløv, J. A., Wewer Albrechtsen, N. J., Kuhre, R. E., Jepsen, S. L., Hornburg, D., Pedersen, J., Jensen, E. P., Galsgaard, K. D., Winther-Sørensen, M., Ørgaard, A., Deacon, C. F., Mann, M., Kissow, H., Hartmann, B. & Holst, J. J., Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  48 Citations (Scopus)
• 2016

  Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

  Albrechtsen, N. J. W., Kuhre, R. E., Windeløv, J. A., Ørgaard, A., Deacon, C. F., Kissow, H., Hartmann, B. & Holst, J. J., 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  35 Citations (Scopus)

• Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes

  Albrechtsen, N. J. W., Albrechtsen, R., Bremholm, L., Svendsen, B., Kuhre, R. E., Poulsen, S. S., Christiansen, C. B., Jensen, E. P., Janus, C., Hilsted, L., Deacon, C. F., Hartmann, B. & Holst, J. J., 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  27 Citations (Scopus)

  892 Downloads (Pure)

• Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

  Wewer Albrechtsen, N. J., Hornburg, D., Albrechtsen, R., Svendsen, B., Toräng, S., Jepsen, S. L., Kuhre, R. E., Hansen, M., Janus, C., Floyd, A., Lund, A., Lauritsen, T. V., Knop, F. K., Vestergaard, H., Deacon, C. F., Meissner, F., Mann, M., Holst, J. J. & Hartmann, B., May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  56 Citations (Scopus)

• Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.

  Kuhre, R. E., Albrechtsen, N. J. W., Deacon, C. F., Balk-Møller, E., Rehfeld, J. F., Relman, F., Gribble, F. M. & Holst, J. J., 2016, In: Journal of Molecular Endocrinology. 56, p. 201-211

  Research output: Contribution to journal › Journal article › Research › peer-review
  84 Citations (Scopus)

• The biology of glucagon and the consequences of hyperglucagonemia

  Wewer Albrechtsen, N. J., Kuhre, R. E., Pedersen, J., Knop, F. K. & Holst, J. J., 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  96 Citations (Scopus)

  360 Downloads (Pure)

• The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

  Albrechtsen, N. J. W., Kuhre, R. E., Toräng, S. & Holst, J. J., 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  57 Citations (Scopus)

  138 Downloads (Pure)
• 2015

  Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

  Brighton, C. A., Rievaj, J., Kuhre, R. E., Glass, L. L., Schoonjans, K., Holst, J. J., Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  271 Citations (Scopus)

• Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx

  Kuhre, R. E., Bechmann, L. E., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 21 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, p. E1123–E1130 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  37 Citations (Scopus)

• Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

  Kuhre, R. E., Wewer Albrechtsen, N. J., Hartmann, B., Deacon, C. F. & Holst, J. J., Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  62 Citations (Scopus)

• Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

  Kuhre, R. E., Frost, C. R., Svendsen, B. & Holst, J. J., Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  141 Citations (Scopus)

• Stability of glucagon-like peptide-1 and glucagon in human plasma

  Albrechtsen, N. J. W., Bak, M. J., Hartmann, B., Christensen, L. W., Kuhre, R. E., Deacon, C. & Holst, J. J., 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

• Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine

  Christensen, L. W., Kuhre, R. E., Janus, C., Svendsen, B. & Holst, J. J., 17 Sep 2015, In: Physiological Reports. 3, 9, p. 1-13 13 p., e122551.

  Research output: Contribution to journal › Journal article › Research › peer-review
  80 Citations (Scopus)
• 2014

  Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

  Kuhre, R. E., Gribble, F. M., Hartmann, B., Reimann, F., Windeløv, J. A., Rehfeld, J. F. & Holst, J. J., 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  97 Citations (Scopus)

• GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

  Kuhre, R. E., Albrechtsen, N. J. W., Windeløv, J. A., Svendsen, B., Hartmann, B. & Holst, J. J., 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  50 Citations (Scopus)