Signe Schultz Pedersen

Search results

• 2025

  Protection of beta cells against cytokine-induced apoptosis by the gut microbial metabolite butyrate

  Jørgensen, K. S., Pedersen, S. S., Hjorth, S. A., Billestrup, N. & Prause, M., 2025, In: FEBS Journal. 292, 1, p. 226-240

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2024

  Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

  Pedersen, S. S., Ingerslev, L. R., Olsen, M., Prause, M. & Billestrup, N., 2024, In: FEBS Journal. 291, 3, p. 566-583

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)
• 2023

  Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

  Pedersen, S. S., Prause, M., Sørensen, C., Størling, J., Moritz, T., Mariño, E. & Billestrup, N., 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  9 Citations (Scopus)

  35 Downloads (Pure)
• 2022

  Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

  Pedersen, S. S., Prause, M., Williams, K., Barrès, R. & Billestrup, N., 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  40 Downloads (Pure)

• Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis

  Andersen, R. C., Schmidt, J. H., Rombach, J., Lycas, M. D., Christensen, N. R., Lund, V. K., Stapleton, D. S., Pedersen, S. S., Olsen, M. A., Stoklund, M., Noes-Holt, G., Nielsen, T. T. E., Keller, M. P., Jansen, A. M., Herlo, R., Pietropaolo, M., Simonsen, J. B., Kjærulff, O., Holst, B., Attie, A. D. & 2 others, Gether, U. & Madsen, K. L., 2022, In: Journal of Clinical Investigation. 132, 5, e144904.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  48 Downloads (Pure)
• 2021

  Butyrate protects pancreatic beta cells from cytokine-induced dysfunction

  Prause, M., Pedersen, S. S., Tsonkova, V., Qiao, M. & Billestrup, N., 2021, In: International Journal of Molecular Sciences. 22, 19, 18 p., 10427.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

  50 Downloads (Pure)

• Partially Hydrolysed Whey Has Superior Allergy Preventive Capacity Compared to Intact Whey Regardless of Amoxicillin Administration in Brown Norway Rats

  Graversen, K. B., Larsen, J. M., Pedersen, S. S., Sørensen, L. V., Christoffersen, H. F., Jacobsen, L. N., Halken, S., Licht, T. R., Bahl, M. I. & Bøgh, K. L., 2021, In: Frontiers in Immunology. 12, 16 p., 705543.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  11 Citations (Scopus)

  3 Downloads (Pure)