Signe Simonsen

Search results

• 2025

  Synthesis and evaluation of fluorinated tetrahydrocarbazoles as probes in NMR based binding assay of the E. coli β sliding clamp

  Olsen, C. E., Simonsen, S., Merugu, S. R., Eigner, V., Aachmann, F. L., Kragelund, B. B., Sundby, E. & Hoff, B. H., 2025, In: Bioorganic and Medicinal Chemistry. 122, 14 p., 118139.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Downloads (Pure)
• 2024

  Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

  Olsen, J. G., Prestel, A., Kassem, N., Broendum, S. S., Shamim, H. M., Simonsen, S., Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, C., Carr, A. M., Crehuet, R., Nielsen, O. & Kragelund, B. B., 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  37 Downloads (Pure)

• SLiM-mediated interactions of DNA sliding clamps and implications for dynamics and drug discovery

  Simonsen, S., 2024, Department of Biology, Faculty of Science, University of Copenhagen. 254 p.

  Research output: Book/Report › Ph.D. thesis

  File

• The bacterial DNA sliding clamp, β-clamp: structure, interactions, dynamics and drug discovery

  Simonsen, S., Søgaard, C. K., Olsen, J. G., Otterlei, M. & Kragelund, B. B., 2024, In: Cellular and Molecular Life Sciences. 81, 1, 25 p., 245.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  9 Downloads (Pure)
• 2021

  Identification of a Catalytic Nucleophile-Activating Network in the endo-α-N-Acetylgalactosaminidase of Family GH101

  Hansen, A. L., Koivisto, J. M., Simonsen, S., Dong, Z., Crehuet, R., Hansen, D. K. & Willemoës, M., 2021, In: Biochemistry. 60, 45, p. 3398-3407 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  9 Downloads (Pure)