Sofia Hammami Bomholtz

Research output

Research output per year 2007 2009 2010 2013 2018 2020 2022

• 287 Citations
• 17 Journal article
• 5 Conference abstract in journal
• 1 Ph.D. thesis
• 1 Conference abstract for conference

Research output per year

Research output per year

Search results

• 2022

  Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation

  Vad, O. B., Yan, Y., Denti, F., Ahlberg, G., Refsgaard, L., Bomholtz, S. H., Santos, J. L., Rasmussen, S., Haunsø, S., Svendsen, J. H., Christophersen, I. E., Schmitt, N., Olesen, M. S. & Bentzen, B. H., 2022, In: Frontiers in Genetics. 13, 8 p., 806429.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  25 Downloads (Pure)
• 2020

  Functional phenotype variations of two novel K_v 7.1 mutations identified in patients with Long QT syndrome

  Hammami Bomholtz, S., Refaat, M., Buur Steffensen, A., David, J-P., Espinosa, K., Nussbaum, R., Wojciak, J., Hjorth Bentzen, B., Scheinman, M. & Schmitt, N., 2020, In: Pacing and Clinical Electrophysiology. 43, 2, p. 210-216 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  4 Citations (Scopus)

• Inhibition of K_Ca2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

  Diness, J. G., Abildgaard, L., Bomholtz, S. H., Skarsfeldt, M. A., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Bentzen, B. H., 2020, In: Frontiers in Pharmacology. 11, 10 p., 749.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  48 Downloads (Pure)

• Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

  Bentzen, B. H., Bomholtz, S. H., Simó-Vicens, R., Folkersen, L., Abildgaard, L., Speerschneider, T., Muthukumarasamy, K. M., Edvardsson, N., Sørensen, U. S., Grunnet, M. & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 610.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  84 Downloads (Pure)
• 2019

  The K_Ca2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

  Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, S. H., Abildgaard, L., Jespersen, T., Sørensen, U. S., Grunnet, M., Bentzen, B. H. & Diness, J. G., 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  8 Citations (Scopus)

  160 Downloads (Pure)
• 2018

  2,6-Bis(2-Benzimidazolyl)Pyridine (BBP) Is a Potent and Selective Inhibitor of Small Conductance Calcium-Activated Potassium (SK) Channels

  Simó-Vicens, R., Bomholtz, S. H., Sørensen, U. S. & Bentzen, B. H., 3 Dec 2018, In: Frontiers in Pharmacology. 9, 1409.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  237 Downloads (Pure)

• Atrium-specific ion channels in the zebrafish: A role of Iin atrial repolarization

  Skarsfeldt, M. A., Bomholtz, S. H., Lundegaard, P. R., Lopez-Izquierdo, A., Tristani-Firouzi, M. & Bentzen, B. H., Jul 2018, In: Acta Physiologica (Print). 223, 3, 17 p., e13049.

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• PKD Phosphorylation as Novel Pathway of K_V11.1 Regulation

  Steffensen, A. B., Bomholtz, S. H., Andersen, M. N., Olsen, J. V., Mutsaers, N., Lundegaard, P. R., Lundby, A. & Schmitt, N., 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  136 Downloads (Pure)

• Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus

  Söderhielm, P. C., Klein, A. B., Bomholtz, S. H. & Jensen, A. A., 2018, In: Life Sciences. 214, p. 145-152

  Research output: Contribution to journal › Journal article › Research › peer-review
  6 Citations (Scopus)
• 2017

  Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

  Diness, J. G., Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, P. R., Citerni, C., Sauter, D. R. P., Bomholtz, S. H., Svendsen, J. H., Olesen, S-P., Sørensen, U. S., Jespersen, T., Grunnet, M. & Bentzen, B. H., 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  59 Citations (Scopus)

  396 Downloads (Pure)
• 2016

  pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

  Skarsfeldt, M. A., Jepps, T. A., Bomholtz, S. H., Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, J. H., Diness, J. G., Grunnet, M., Schmitt, N., Olesen, S-P. & Bentzen, B. H., Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  18 Citations (Scopus)
• 2015

  Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

  Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, S. H., Nielsen, M. S., Grunnet, M., Bentzen, B. H. & Jespersen, T., Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  26 Citations (Scopus)
• 2014

  Cell volume changes regulate Slick (Slo2.1), but not Slack (Slo2.2) K⁺ channels

  Tejada, M. D. L. A., Stople, K., Bomholtz, S. H., Meinild, A-K., Poulsen, A. N. & Klærke, D. A., 2014, In: P L o S One. 9, 10, p. 1-8 8 p., e110833.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  18 Citations (Scopus)

  990 Downloads (Pure)
• 2013

  A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

  Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, S. H., Olesen, S-P., Abriel, H., Jespersen, T. & Rasmussen, H. B., 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  27 Citations (Scopus)

• Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges

  Bomholtz, S. H., Willumsen, N. J., Meinild, A-K., Klærke, D. A. & Novak, I., 2013, In: Acta Physiologica (Print). 207, 3, p. 503-515 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)
• 2012

  Evidence for a common pharmacological interaction site on K(Ca)2 channels providing both selective activation and selective inhibition of the human K(Ca)2.1 subtype

  Hougaard, C., Hammami, S., Eriksen, B. L., Sørensen, U. S., Jensen, M. L., Strøbæk, D., Christophersen, P. & Bomholtz, S. H., Feb 2012, In: Molecular Pharmacology. 81, 2, p. 210-9 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  23 Citations (Scopus)
• 2011

  Upregulation of KCNQ1 currents by the KCNE1 beta subunit is not caused by insertion of KCNQ1 into the membrane

  Hammami, S., Willumsen, N. & Klærke, D. A., 2011, (Submitted). 1 p.

  Research output: Contribution to conference › Conference abstract for conference › Research
• 2010

  KCNE1-induced increase in KCNQ1 currents is not mediated through enhanced membrane expression

  Hammami, S., Willumsen, N. J. & Klærke, D. A., Apr 2010, In: The FASEB Journal. 24, 610.6

  Research output: Contribution to journal › Conference abstract in journal › Research

• KCNQ1 channel response to cell volume changes is not mediated by ATP release

  Hammami, S., Willumsen, N., Novak, I. & Klærke, D. A., 2010, In: Acta Physiologica Scandinavica. Supplementum. 198, Suppl 677, p. 213 1 p.

  Research output: Contribution to journal › Conference abstract in journal › Research

• Mechanism for strict regulation of certain K⁺ channels by small, fast changes in cell volume

  Tejada, M. D. L. A., Stolpe, K., Hammami, S., Willumsen, N. J., Poulsen, A. N. & Klærke, D. A., 2010, In: Biophysical Journal. Supp. 1, p. 534a

  Research output: Contribution to journal › Conference abstract in journal › Research

• Mechanisms underlying KCNQ1channel cell volume sensitivity

  Hammami, S., 2010, Biologisk Institut: Museum Tusculanum. 112 p.

  Research output: Book/Report › Ph.D. thesis › Research
• 2009

  Cell volume and membrane stretch independently control K+ channel activity

  Bomholtz, S. H., Willumsen, N. J., Olsen, H. L., Morera, F. J., Latorre, R. & Klaerke, D. A., 2009, In: Journal of Physiology. 587, Pt 10, p. 2225-31 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  33 Citations (Scopus)

• Interaction of purinergic receptors, K⁺ channels and aquaporins in cell volume regulation

  Hammami, S., Novak, I., Willumsen, N. J. & Klærke, D. A., 2009, In: Journal of Physiological Sciences. 1, p. 387 1 p.

  Research output: Contribution to journal › Conference abstract in journal › Research
• 2007

  Cell volume and membrane stretch independently control K⁺ channel activity

  Hammami, S., Willumsen, N. J. & Klærke, D. A., 2007, In: The FASEB Journal. 5, p. A539-A539 1 p.

  Research output: Contribution to journal › Conference abstract in journal › Research