Research output per year
Research output per year
Personal profile
Short presentation
My research aim is cross-disciplinary focusing on the interface between physical chemistry, biophysics, biology and pharmaceutical sciences. I explore the barrier interactions between biological membranes, the skin and mucus barrier, and advanced drug delivery systems (DDS) or components hereof e.g., permeation enhancers and solid-state formulations intended for delivery of biopharmaceuticals. My research includes small as well as large molecules. I have a particular interest in how diseases in the barrier affects drug uptake and barrier interaction. By combining advanced biophysical techniques such as synchrotron X-ray and neutron scattering, rheology, rheo-microscopy, advanced microscopy (cryo-SEM and TEM) and thermal characterization with in vitro and in vivo models, I am currently developing a multimodal research platform to explore interactions between the skin barrier and delivery systems being deep eutectics and ionic liquids.
Introductory remarks on publicationslist
Maternaty leaves:
- January 2017-Spring 2018
- February 2015-February 2016
- March 2019-August 2020
Education/Academic qualification
Food biophysics, PhD, Fat Crystallization in Dairy Products. Rheology and Microstructure., University of Copenhagen
1 Mar 2010 → 28 Feb 2013
Award Date: 19 Apr 2013
Pharmacist, MSc.pharm., Skin penetration of PEGylated liposomes
1 Sept 2007 → 7 Aug 2009
Award Date: 7 Aug 2009
Pharmacy, BSc.pharm.
1 Sept 2004 → 30 Jun 2008
External positions
Pharmacist, Landsapoteket Dronning Ingrids Hospital
1 Sept 2009 → 28 Feb 2010
MSc. student, LEO Pharma
1 Feb 2009 → 31 Jul 2009
QC Student assistant, LEO Pharma
1 Feb 2005 → 30 Nov 2007
Keywords
- Former Faculty of Pharmaceutical Sciences
- Fatty acids
- Faculty of Science
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro
Rønholt, S., Kristensen, M. & Nielsen, H. M., 2015, Cell-penetrating peptides : Methods and Protocols. Langel, Ü. (ed.). Humana Press, Vol. 1324. p. 261-277 17 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The effect of butter grains on physical properties of butter-like emulsions
Rønholt, S., Buldo, P., Mortensen, K., Andersen, U., Knudsen, J. C. & Wiking, L., 2014, In: Journal of Dairy Science. 97, 4, p. 1929-1938 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
Metodeudvikling: Reologi til bestemmelse af fedtbaserede produkters materialeegenskaber
Rønholt, S., Knudsen, J. C. & Mortensen, K., 2013, In: Dansk Kemi. 94, 11, p. 33-34 2 p.Research output: Contribution to journal › Journal article › Communication
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Fat crystallization in dairy products: Rheology and microstructure of fat crystals
Rønholt, S., 2013, Department of Food Science, University of Copenhagen. 283 p.Research output: Book/Report › Ph.D. thesis
File -
Effect of cream cooling rate and water content on butter microstructure during four weeks of storage
Rønholt, S., Kirkensgaard, J. J. K., Mortensen, K. & Knudsen, J. C., 2014, In: Food Hydrocolloids. 34, p. 169-176 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
40 Citations (Scopus) -
The effect of capacity, rotational speed and storage on crystallization and rheological properties of puff pastry butter
Rønholt, S., Kirkensgaard, J. J. K., Høyer, K. F., Mortensen, K. & Knudsen, J. C., 2014, In: Journal of the American Oil Chemists' Society. 91, 1, p. 29-38Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
The effective factors on the structure of butter and other milk fat-based products
Rønholt, S., Mortensen, K. & Knudsen, J. C., 2013, In: Comprehensive Reviews in Food Science and Food Safety. 12, 5, p. 468-482 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
79 Citations (Scopus) -
Small deformation rheology for characterization of anhydrous milk fat/rapeseed oil samples
Rønholt, S., Mortensen, K. & Knudsen, J. C., 2014, In: Journal of Texture Studies. 45, 1, p. 20-29 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
8 Citations (Scopus)
Activities
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2014 AAPS Annual meeting and EXPO
Rønholt, S. (Speaker)
2 Nov 2014 → 6 Nov 2014Activity: Participating in an event - types › Participation in workshop, seminar, course
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COMPACT
Rønholt, S. (Speaker)
3 Feb 2015 → 5 Feb 2015Activity: Participating in an event - types › Participation in workshop, seminar, course
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EUPATI
Rønholt, S. (Speaker)
1 Jan 2014 → …Activity: Participating in an event - types › Participation in workshop, seminar, course
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Cell Penetrating Peptides
Rønholt, S. (Participant)
7 Oct 2013 → 13 Oct 2013Activity: Participating in an event - types › Participation in workshop, seminar, course
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Copenhagen Summer University
Nielsen, H. M. (Organizer) & Harloff-Helleberg, S. (Organizer)
14 Aug 2017 → 18 Aug 2017Activity: Participating in an event - types › Organisation of and participation in conference
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Assessment of Mucoadhesion Using Small Deformation Rheology Revisited
Harloff-Helleberg, S. (Other) & Nielsen, H. M. (Other)
3 Apr 2017 → 6 Apr 2017Activity: Talk or presentation types › Lecture and oral contribution
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Journal of Food Engineering (Journal)
Harloff-Helleberg, S. (Peer reviewer)
2017 → …Activity: Peer-review and editorial work types › Peer review of manuscripts › Research
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Biopharmaceutical delivery - oral delivery
Harloff-Helleberg, S. (Invited speaker)
19 Aug 2016Activity: Talk or presentation types › Lecture and oral contribution