Personal profile
CV
- Associate Professor at the Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 2008.
- Assistant Professor, Department of Pharmaceutics and Analytical Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, 2003.
- PhD, Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, 2003.
Primary fields of research
- Design of intra-articular oil injectables aiming at local prolonged balanced analgesia
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A novel prodrug principle (patented) to achieve localized and sustained NSAID action after joint injection.
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Characterization of in situ suspension-forming injectables for sustained drug delivery
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Development and utility of in vitro release methods to characterize in vivo performance of depot formulations for the subcutaneous and intra-articular route of administration.
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In situ formed liquid crystalline nanostructures as sustained release injectable formulations.
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Osteoarthritis – Improved therapy trough drug targeting to the articular cartilage.
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Lymphatic targeting and biodistribution of drug nanocarriers based on cubosomes and hexosomes.
- Microfluidic characterization of drug dissolution phenomena
Teaching
- Pharmaceutical Physical Chemistry
- Pharmaceutical Preformulation
- Bachelorproject in Pharmacy
- Supervision of master and PhD students
Keywords
- Former Faculty of Pharmaceutical Sciences
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Assessment of subcutaneously administered insulins using in vitro release cartridge: Medium composition and albumin binding
Bock, F., Zivlaei, N., Nguyen, A. T. H., Larsen, S. W., Lu, X. & Østergaard, J., 2024, In: International Journal of Pharmaceutics. 661, 12 p., 124436.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)58 Downloads (Pure) -
Development of a bio-relevant in vitro release testing method for subcutaneous and intramuscular oil depot formulations
Østergaard, J., Mertz, N., Gancho, V., Le, A., Barber, M., Bezawada, P., Larsen, S. W., O'Brien Laramy, M. N. & Rohit, J., 2024, In: Journal of Drug Delivery Science and Technology. 102, 11 p., 106412.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)30 Downloads (Pure) -
Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, S. W., Müllertz, A., Box, K. & Østergaard, J., 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)79 Downloads (Pure) -
Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization
Bock, F., Hu, A., Cicale, V., Larsen, S. W., Lu, X. & Østergaard, J., 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)42 Downloads (Pure) -
Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties
Hedengran, A., Freiberg, J. C., Hansen, P. M., Jacobsen, J., Larsen, S. W., Harloff‐helleberg, S., Freude, K., Boix‐lemonche, G., Petrovski, G., Heegaard, S. & Kolko, M., 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Citations (Scopus)90 Downloads (Pure) -
Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro
Huang, J., Jacobsen, J., Genina, N., Larsen, S. W., Nielsen, H. M., Müllertz, A. & Mu, H., 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)105 Downloads (Pure) -
Investigation of diclofenac release and dynamic structural behavior of non-lamellar liquid crystal formulations during in situ formation by UV–Vis imaging and SAXS
Mertz, N., Bock, F., Østergaard, J., Yaghmur, A. & Weng Larsen, S., 2022, In: International Journal of Pharmaceutics. 623, 121880.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)152 Downloads (Pure) -
Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance
Bock, F., Bøtker, J. P., Larsen, S. W., Lu, X. & Østergaard, J., 2022, In: International Journal of Molecular Sciences. 23, 7, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)97 Downloads (Pure)