Thomas Mandrup-Poulsen

Research output

Research output per year 1985 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2018 2019 2020 2024

• 13613 Citations
• 181 Journal article
• 5 Conference abstract for conference
• 5 Review
• 3 Book chapter
• 14 More
  • 3 Poster
  • 3 Comment/debate
  • 3 Conference abstract in journal
  • 2 Letter
  • 2 Other contribution
  • 1 Article in proceedings

Research output per year

Research output per year

Search results

• 2024

  Nutrient Abundance Signals the Changing of the Seasons by Phosphorylating PER2

  Levine, D. C., Reeh, R. H., McMahon, T., Mandrup-Poulsen, T., Fu, Y-H. & Ptáček, L. J., 30 Jan 2024, In: bioRxiv.

  Research output: Contribution to journal › Journal article › Research

• Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

  Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, J. H., Porse, B. T., Mandrup-Poulsen, T. & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  6 Downloads (Pure)

• Tipping-point transition from transient to persistent inflammation in pancreatic islets

  Holst-hansen, T., Nielsen, P. Y., Jensen, M. H., Mandrup-poulsen, T. & Trusina, A., 12 Sep 2024, In: npj Systems Biology and Applications. 10, 1, 13 p., 102.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
• 2023

  A randomised, double-blind, crossover study of the effect of the fluoroquinolone moxifloxacin on glucose levels and insulin sensitivity in young men and women

  Juhl, C. R., Burgdorf, J., Knudsen, C., Lubberding, A. F., Veedfald, S., Isaksen, J. L., Hartmann, B., Frikke-Schmidt, R., Mandrup-Poulsen, T., Holst, J. J., Kanters, J. K. & Torekov, S. S., 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 98-109

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  70 Downloads (Pure)

• Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

  Sileikaite-Morvaközi, I., Hansen, W. H., Davies, M. J., Mandrup-Poulsen, T. & Hawkins, C. L., 2023, In: International Journal of Molecular Sciences. 24, 19, 13 p., 14585.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  17 Downloads (Pure)

• FK506-Binding Protein 2 Participates in Proinsulin Folding

  Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, Borowiak, M., Wierer, M., MacDonald, P. E., Mandrup-Poulsen, T. & Marzec, M. T., 2023, In: Biomolecules. 13, 1, 20 p., 152.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  2 Citations (Scopus)

  39 Downloads (Pure)

• Interaction Between Dietary Iron Intake and Genetically Determined Iron Overload: Risk of Islet Autoimmunity and Progression to Type 1 Diabetes in the TEDDY Study

  Ullitz Thorsen, S., Liu, X., Kataria, Y., Mandrup-poulsen, T., Kaur, S., Uusitalo, U., Virtanen, S. M., Norris, J., Rewers, M., Hagopian, W., Yang, J., She, J., Akolkar, B., Rich, S. S., Aronsson, C. A., Lernmark, Å., Ziegler, A., Toppari, J., Krischer, J. P., Parikh, H. M. & 31 others, Ellervik, C., Svensson, J., Rewers, M., Barbour, A., Bautista, K., Baxter, J., Felipe-morales, D., Frohnert, B. I., Stahl, M., Gesualdo, P., Hoffman, M., Karban, R., Liu, E., Munoz, A., Norris, J., O’donnell, H., Peacock, S., Shorrosh, H., Steck, A., Stern, M., Waugh, K., Toppari, J., Simell, O. G., Adamsson, A., Ahonen, S., Åkerlund, M., Anttila, S., Hakola, L., Hekkala, A., Agardh, D. & Environmental Determinants of Diabetes in the Young (TEDDY) Group, 2023, In: Diabetes Care. 46, 5, p. 1-5

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  2 Citations (Scopus)

  7 Downloads (Pure)

• Obesity-induced changes in gene expression in feline adipose and skeletal muscle tissue

  Stenberg, K., Novotny, G. W., Lutz, T. A., Mandrup-Poulsen, T. & Bjørnvad, C. R., 2023, In: Journal of Animal Physiology and Animal Nutrition. 107, 5, p. 1262 - 1278

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  2 Citations (Scopus)

  14 Downloads (Pure)
• 2022

  A Blunted GPR183/Oxysterol Axis during Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung during Mycobacterium tuberculosis Infection

  Ngo, M. D., Bartlett, S., Bielefeldt-Ohmann, H., Foo, C. X., Sinha, R., Arachchige, B. J., Reed, S., Mandrup-Poulsen, T., Rosenkilde, M. M. & Ronacher, K., 2022, In: Journal of Infectious Diseases. 225, 12, p. 2219-2228

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  14 Citations (Scopus)

  24 Downloads (Pure)

• Celebrities in the heart, strangers in the pancreatic beta cell: Voltage-gated potassium channels K_v7.1 and K_v11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes

  Lubberding, A. F., Juhl, C. R., Skovhoj, E. Z., Kanters, J. K., Mandrup-Poulsen, T. & Torekov, S. S., 2022, In: Acta Physiologica. 234, 3, 18 p., 13781.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

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  63 Downloads (Pure)

• Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells

  Khilji, M. S., Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., Buus, S., Nielsen, M., Klusek, J., Mandrup-Poulsen, T., Pandey, K., Purcell, A. W. & Marzec, M. T., 2022, In: Biomedicines. 10, 4, 814.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  36 Downloads (Pure)
• 2021

  Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

  Lubberding, A. F., Zhang, J., Lundh, M., Nielsen, T. S., Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, M. B., Treebak, J. T., Holst, J. J., Kanters, J. K., Mandrup-Poulsen, T., Jespersen, T., Emanuelli, B. & Torekov, S. S., 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  11 Citations (Scopus)

  54 Downloads (Pure)

• Divalent metal transporter 1 knock-down modulates il-1β mediated pancreatic beta-cell pro-apoptotic signaling pathways through the autophagic machinery

  Kang, T., Huang, H., Mandrup-Poulsen, T. & Larsen, M. R., 2021, In: International Journal of Molecular Sciences. 22, 15, 25 p., 8013.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  5 Citations (Scopus)

  12 Downloads (Pure)

• Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity

  Andersen, P. A. K., Petrenko, V., Rose, P. H., Koomen, M., Fischer, N., Ghiasi, S. M., Dahlby, T., Dibner, C. & Mandrup-Poulsen, T., 2021, In: International Journal of Molecular Sciences. 22, 1, p. 1-25 83.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  2 Citations (Scopus)

  31 Downloads (Pure)

• The role of RNA oxidation in islet dysfunction in Type 2 diabetes

  Sileikaite, I., Davies, M. J., Mandrup-Poulsen, T. & Hawkins, C. L., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1 , p. S37-S38

  Research output: Contribution to journal › Conference abstract in journal › Research
• 2020

  Combination of ferric ammonium citrate with cytokines involved in apoptosis and insulin secretion of human pancreatic beta cells related to diabetes in thalassemia

  Rattanaporn, P., Tongsima, S., Mandrup-Poulsen, T., Svasti, S. & Tanyong, D., 2020, In: PeerJ. 8, e9298.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  1 Citation (Scopus)

  51 Downloads (Pure)

• Enhancer of Zeste Homolog 2 (EZH2) Mediates Glucolipotoxicity-Induced Apoptosis in beta-Cells

  Dahlby, T., Simon, C., Backe, M. B., Dahllof, M. S., Holson, E., Wagner, B. K., Boni-Schnetzler, M., Marzec, M. T., Lundh, M. & Mandrup-Poulsen, T., 2020, In: International Journal of Molecular Sciences. 21, 21, 18 p., 8016.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  5 Citations (Scopus)

  31 Downloads (Pure)

• GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity

  Bartlett, S., Gemiarto, A. T., Ngo, M. D., Sajiir, H., Hailu, S., Sinha, R., Foo, C. X., Kleynhans, L., Tshivhula, H., Webber, T., Bielefeldt-Ohmann, H., West, N. P., Hiemstra, A. M., MacDonald, C. E., Christensen, L. V. V., Schlesinger, L. S., Walzl, G., Rosenkilde, M. M., Mandrup-Poulsen, T. & Ronacher, K., 2020, In: Frontiers in Immunology. 11, 11 p., 601534.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  1 Citation (Scopus)

  89 Downloads (Pure)

• Interleukin-6 receptor blockade or TNF alpha inhibition for reducing glycaemia in patients with RA and diabetes: post hoc analyses of three randomised, controlled trials

  Genovese, M. C., Burmester, G. R., Hagino, O., Thangavelu, K., Iglesias-Rodriguez, M., John, G. S., Gonzalez-Gay, M. A., Mandrup-Poulsen, T. & Fleischmann, R., 2020, In: Arthritis Research & Therapy. 22, 1, 12 p., 206.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  2 Citations (Scopus)

  15 Downloads (Pure)

• Mitophagy protects beta cells from inflammatory damage in diabetes

  Sidarala, V., Pearson, G. L., Parekh, V. S., Thompson, B., Christen, L., Gingerich, M. A., Zhu, J., Stromer, T., Ren, J., Reck, E. C., Chai, B., Corbett, J. A., Mandrup-Poulsen, T., Satin, L. S. & Soleimanpour, S. A., 2020, In: JCI insight. 5, 24, 15 p., 141138.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  73 Citations (Scopus)

  14 Downloads (Pure)

• Pancreatic beta-cells respond to fuel pressure with an early metabolic switch

  Malinowski, R. M., Ghiasi, S. M., Mandrup-Poulsen, T., Meier, S., Lerche, M. H., Ardenkjaer-Larsen, J. H. & Jensen, P. R., 2020, In: Scientific Reports. 10, 1, 11 p., 15413.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  20 Downloads (Pure)

• Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case–control ancillary study

  Miettinen, M. E., Niinistö, S., Erlund, I., Cuthbertson, D., Nucci, A. M., Honkanen, J., Vaarala, O., Hyöty, H., Krischer, J. P., Knip, M., Virtanen, S. M., Mandrup-Poulsen, T. & TRIGR Investigators, 2020, In: Diabetologia. 63, 4, p. 780-787 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  30 Citations (Scopus)

  8 Downloads (Pure)

• The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

  Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, T., 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  4 Citations (Scopus)

  74 Downloads (Pure)

• The inducible beta 5i proteasome subunit contributes to proinsulin degradation in GRP94-deficient beta-cells and is overexpressed in type 2 diabetes pancreatic islets

  Khilji, M. S., Bresson, S. E., Verstappen, D., Pihl, C., Andersen, P. A. K., Agergaard, J. B., Dahlby, T., Bryde, T. H., Klindt, K., Nielsen, C. K., Walentinsson, A., Zivkovic, D., Bousquet, M-P., Tyrberg, B., Richardson, S. J., Morgan, N. G., Mandrup-Poulsen, T. & Marzec, M. T., 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E892-E900

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  8 Citations (Scopus)

• The intermediate proteasome is constitutively expressed in pancreatic beta cells and upregulated by stimulatory, low concentrations of interleukin 1 β

  Khilji, M. S., Verstappen, D., Dahlby, T., Prause, M. C. B., Pihl, C., Bresson, S. E., Bryde, T. H., Andersen, P. A. K., Klindt, K., Zivkovic, D., Bousquet-Dubouch, M. P., Tyrberg, B., Mandrup-Poulsen, T. & Marzec, M. T., 2020, In: PLoS ONE. 15, 2, 21 p., e0222432.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  12 Citations (Scopus)

  99 Downloads (Pure)
• 2019

  Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling

  Ghiasi, S. M., Dahlby, T., Hede Andersen, C., Haataja, L., Petersen, S., Omar-Hmeadi, M., Yang, M., Pihl, C., Bresson, S. E., Khilji, M. S., Klindt, K., Cheta, O., Perone, M. J., Tyrberg, B., Prats, C., Barg, S., Tengholm, A., Arvan, P., Mandrup-Poulsen, T. & Marzec, M. T., Apr 2019, In: Diabetes. 68, 4, p. 747-760 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  46 Citations (Scopus)

• Gluten under graviditeten og risiko for type 1 diabetes hos barnet: [Medicinsk nyhed]

  Mandrup-Poulsen, T., 2019, In: Ugeskrift for Laeger. 22

  Research output: Contribution to journal › Comment/debate › Communication

• Inflammatory and metabolic stress perturbs the beta cell circadian clock: [Meeting Abstract]

  Andersen, P. A. K., Rose, P. H., Koomen, M., Petrenko, V., Dahlby, T., Ghiasi, S. M., Dibner, C. & Mandrup-Poulsen, T., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S120-S120 237.

  Research output: Contribution to journal › Conference abstract in journal › Research

• Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

  Østergaard, H. B., Mandrup-Poulsen, T., Berkelmans, G. F. N., van der Graaf, Y., Visseren, F. L. J. & Westerink, J., 2019, In: Diabetes and Metabolism. 45, 3, p. 254-260 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  14 Citations (Scopus)

• Neuromedin U Does Not Act as a Decretin in Rats

  Kuhre, R. E., Christiansen, C. B., Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, I. M., Mandrup-Poulsen, T., Albrechtsen, R., Rosenkilde, M. M., Hartmann, B., Albrechtsen, N. J. W. & Holst, J. J., 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  9 Citations (Scopus)

  148 Downloads (Pure)

• No direct effect of SGLT2 activity on glucagon secretion

  Kuhre, R. E., Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, N. J. W., Andersen, D. B., Aivazidis, A., Chen, L., Mandrup-Poulsen, T., Ørskov, C., Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, J. J., 2019, In: Diabetologia. 62, 6, p. 1011-1023

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  64 Citations (Scopus)

  135 Downloads (Pure)

• Targeting innate immune mediators in type 1 and type 2 diabetes

  Donath, M. Y., Dinarello, C. A. & Mandrup-Poulsen, T., 2019, In: Nature Reviews. Immunology. 19, 12, p. 734-746

  Research output: Contribution to journal › Review › Research › peer-review
  258 Citations (Scopus)

• The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

  Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, S. S., Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, B. & Mandrup-Poulsen, T., 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  21 Citations (Scopus)

  104 Downloads (Pure)

• Treatment of type 2 diabetes by targeting interleukin-1: a meta-analysis of 2921 patients

  Kataria, Y., Ellervik, C. & Mandrup-Poulsen, T., 2019, In: Seminars in Immunopathology. 41, 4, p. 413-425

  Research output: Contribution to journal › Review › Research › peer-review
  29 Citations (Scopus)

• Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes

  Kjaer, L. K., Cejvanovic, V., Henriksen, T., Hansen, T., Pedersen, O., Christensen, C. K., Torp-Pedersen, C., Gerds, T. A., Brandslund, I., Mandrup-Poulsen, T. & Poulsen, H. E., 3 Jun 2019, In: Free Radical Research. 53, 6, p. 694-703

  Research output: Contribution to journal › Journal article › Research › peer-review
  5 Citations (Scopus)
• 2018

  Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

  Christiansen, C. B., Lind, S. J., Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, R. E., Hartmann, B., Mandrup-Poulsen, T., Deacon, C. F., Albrechtsen, N. J. W. & Holst, J. J., 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

  Research output: Contribution to journal › Journal article › Research › peer-review

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  8 Citations (Scopus)

  137 Downloads (Pure)

• Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

  TRIGR Study Group, 2018, In: J A M A: The Journal of the American Medical Association. 319, 1, p. 38-48

  Research output: Contribution to journal › Journal article › Research › peer-review
  107 Citations (Scopus)

• Glucolipotoxic conditions induce beta-cell iron import, cytosolic ROS formation and apoptosis

  Hansen, J. B., Dos Santos, L. R. B., Liu, Y., Prentice, K. J., Teudt, F., Tonnesen, M., Jonas, J-C., Wheeler, M. B. & Mandrup-Poulsen, T., 2018, In: Journal of Molecular Endocrinology. 61, 2, p. 69-77

  Research output: Contribution to journal › Journal article › Research › peer-review
  29 Citations (Scopus)

• Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing

  Mandrup-Poulsen, T., Feb 2018, In: Nature Reviews Endocrinology. 14, 2, p. 72-74 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  11 Citations (Scopus)

• Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study

  Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, T., Nordestgaard, B. G. & Ellervik, C., 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  27 Citations (Scopus)

• Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

  Ballak, D. B., Li, S., Cavalli, G., Stahl, J. L., Tengesdal, I. W., van Diepen, J. A., Kluck, V., Swartzwelter, B., Azam, T., Tack, C. J., Stienstra, R., Mandrup-Poulsen, T., Seals, D. R. & Dinarello, C. A., 2018, In: Journal of Biological Chemistry. 293, 37, p. 14224-14236

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  45 Citations (Scopus)

• Iron Status and Gestational Diabetes: A Meta-Analysis

  Kataria, Y., Wu, Y., Horskjaer, P. D. H., Mandrup-Poulsen, T. & Ellervik, C., 2018, In: Nutrients. 10, 5, 15 p., 621 .

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

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  63 Citations (Scopus)

  117 Downloads (Pure)

• Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

  Backe, M. B., Andersson, J. L., Bacos, K., Christensen, D. P., Hansen, J. B., Dorosz, J. J., Gajhede, M., Dahlby, T., Bysani, M., Kristensen, L. H., Ling, C., Olsen, L. & Mandrup-Poulsen, T., 15 Jan 2018, In: Molecular and Cellular Endocrinology. 460, p. 47-56 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  24 Citations (Scopus)

• MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

  Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, F. & Mandrup-Poulsen, T., 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

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  16 Citations (Scopus)

  155 Downloads (Pure)

• Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice

  Besançon, A., Goncalves, T., Valette, F., Dahllöf, M. S., Mandrup-Poulsen, T., Chatenoud, L. & You, S., 1 Feb 2018, In: Diabetologia. 61, 2, p. 389-398 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)

• Regulation of the beta-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis

  Ghiasi, S. M., Dahllöf, M. S., Osmai, Y., Osmai, M., Jakobsen, K. K., Aivazidis, A., Tyrberg, B., Perruzza, L., Prause, M. C. B., Christensen, D. P., Fog-Tonnesen, M., Lundh, M., Grassi, F., Chatenoud, L. & Mandrup-Poulsen, T., 2018, In: Molecular and Cellular Endocrinology. 478, p. 106-114

  Research output: Contribution to journal › Journal article › Research › peer-review
  20 Citations (Scopus)

• The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival

  Ghiasi, S. M., Krogh, N., Tyrberg, B. & Mandrup-Poulsen, T., 2018, In: Diabetes. 67, 10, p. 2019-2037 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  15 Citations (Scopus)
• 2017

  A guiding map for inflammation

  Netea, M. G., Balkwill, F., Chonchol, M., Cominelli, F., Donath, M. Y., Giamarellos-Bourboulis, E. J., Golenbock, D., Gresnigt, M. S., Heneka, M. T., Hoffman, H. M., Hotchkiss, R., Joosten, L. A. B., Kastner, D. L., Korte, M., Latz, E., Libby, P., Mandrup-Poulsen, T., Mantovani, A., Mills, K. H. G., Nowak, K. L. & 12 others, O'Neill, L. A., Pickkers, P., van der Poll, T., Ridker, P. M., Schalkwijk, J., Schwartz, D. A., Siegmund, B., Steer, C. J., Tilg, H., van der Meer, J. W. M., van de Veerdonk, F. L. & Dinarello, C. A., 19 Jul 2017, In: Nature Immunology. 18, 8, p. 826-831 6 p.

  Research output: Contribution to journal › Comment/debate › Research › peer-review
  533 Citations (Scopus)

• Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

  Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, T., Pedersen, O., Christensen, C. K., Torp-Pedersen, C., Gerds, T. A., Brandslund, I., Mandrup-Poulsen, T. & Poulsen, H. E., Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  49 Citations (Scopus)

• Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No

  Mandrup-Poulsen, T., Dec 2017, In: Diabetes. 66, 12, p. 2937-2939 3 p.

  Research output: Contribution to journal › Letter › Research › peer-review
  3 Citations (Scopus)