Personal profile
Primary fields of research
Thue W. Schwartz forsker i appetitregulering og udvikling af lægemidler mod fedme. Han forskersgruppe undersøger især hvordan sult og mæthedssignaler transmitteres fra mave til hjernen. Thue W. Schwartz er medstifter af virksomheden 7TM Pharma, hvor han også fungerer som forskningsdirektør. Virksomheden fokuserer på opdagelse og udvikling af nye lægemidler mod fedme, hvor de første - udsprunget af forskningen på KU - nu bliver afprøvet.Keywords
- Faculty of Health and Medical Sciences
- Eating Disorders
- Obesity
- Molecular Pharmacology
Collaborations and top research areas from the last five years
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Challenging activity and signaling bias in tachykinin NK1 and NK2 receptors by truncated neuropeptides
Petersen, J. E., Pavlovskyi, A., Madsen, J. J., Schwartz, T. W., Frimurer, T. M. & Olsen, O. H., 2025, In: Journal of Biological Chemistry. 301, 6, 11 p., 108522.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)15 Downloads (Pure) -
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
Moretti, C. H., Grasset, E., Zhu, J., Yang, G., Olofsson, L. E., Khan, M. T., Bergh, P. O., Oh, J. H., Lundqvist, A., van Gils, T., Krämer, M., Olsson, L. M., Patel, P., Mitteregger, M., Monges, D. E., Dwibedi, C., Krautkramer, K. A., Koopman, N., Henricsson, M. & Macpherson, A. J. & 7 others, , 2025, In: Cell Reports. 44, 10, 21 p., 116434.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Downloads (Pure) -
Intracrine FFA4 signaling controls lipolysis at lipid droplets
O'Brien, S. L., Tripp, E., Barki, N., Blondel-Tepaz, E., Smith, G., Boufersaoui, A., Roberts, J., Pike, J. A., Correia, J., Miljus, T., Bouvier, M., Tennant, D. A., Hudson, B. D., Gerhart-Hines, Z., Milligan, G., Schwartz, T. W. & Calebiro, D., 2025, In: Nature Chemical Biology. 22, p. 109–119Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
Neurons Co-Expressing GLP-1, CCK, and PYY Receptors Particularly in Right Nodose Ganglion and Innervating Entire GI Tract in Mice
Lansbury, E. L., Vana, V., Lund, M. L., Ludwig, M. Q., Mamedova, E., Gautron, L., Arnold, M., Egerod, K. L., Kuhre, R. E., Holst, J. J., Rekling, J., Schwartz, T. W., Pankratova, S. & Dmytriyeva, O., 2025, In: International Journal of Molecular Sciences. 26, 5, 23 p., 2053.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)12 Downloads (Pure) -
Shaping the future of cardiometabolic innovation: advances and opportunities
Clemmensen, C., Gerhart-Hines, Z., Schwartz, T. W., Zierath, J. R. & Sakamoto, K., 2025, In: Nature Metabolism. 7, 8, p. 1495–1497 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
2 Citations (Scopus) -
Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine
Agueda-Oyarzabal, M., Isidor, M. S., Plucińska, K., Ingerslev, L. R., Dmytriyeva, O., Petersen, P. S. S., Laftih, S., Pontoppidan, A. B., Henningsen, J. B., Rupar, K., Brown, E. L., Schwartz, T. W., Barrès, R., Gerhart-Hines, Z., Schéele, C. C. & Emanuelli, B., 2025, In: Molecular Metabolism. 93, 15 p., 102102.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)38 Downloads (Pure) -
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
Christiansen, M., Burm, H. B., Schmidt, J. H., Skov, L. J., Andersen, R. C., Bowin, C. F., Støier, J. F., Jensen, K. L., Posselt, L. P., Dmytriyeva, O., Sørensen, A. T., Egerod, K. L., Holst, B., Rickhag, M., Schwartz, T. W. & Gether, U., 2024, In: Cell Reports. 43, 7, 23 p., 114509.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)54 Downloads (Pure) -
GLP-1-directed NMDA receptor antagonism for obesity treatment
Petersen, J., Ludwig, M. Q., Juozaityte, V., Ranea-Robles, P., Svendsen, C., Hwang, E., Kristensen, A. W., Fadahunsi, N., Lund, J., Breum, A. W., Mathiesen, C. V., Sachs, L., Moreno-Justicia, R., Rohlfs, R., Ford, J. C., Douros, J. D., Finan, B., Portillo, B., Grose, K. & Petersen, J. E. & 13 others, , 2024, In: Nature. 629, 8014, p. 1133–1141Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile64 Citations (Scopus)165 Downloads (Pure)