Research output per year
Research output per year
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand
Chałupnik, P., Marek, A., Hovah, M. E. L., Pickering, D. S., Temperini, P., Donbosco, S., Szymańska, E. & Johansen, T. N., 2024, In: Journal of Labelled Compounds and Radiopharmaceuticals. 67, 4, p. 120-130Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Downloads (Pure) -
Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists
Chałupnik, P., Vialko, A., Pickering, D. S., Nielsen, B., Bay, Y., Kristensen, A. S., Hinkkanen, M., Szczepańska, K., Karcz, T., Latacz, G., Johansen, T. N. & Szymanska, E. M., 2023, In: ChemMedChem. 18, 18, 15 p., e202300278.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure) -
Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype
Chałupnik, P., Vialko, A., Pickering, D. S., Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, A. A., Nielsen, B., Bay, Y., Kristensen, A. S., Johansen, T. N., Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)53 Downloads (Pure) -
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds
Pallesen, J. S., Narayanan, D., Tran, K. T., Solbak, S. M. Ø., Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, T. N., Popowicz, G. M., Sattler, M., Gajhede, M. & Bach, A., 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Citations (Scopus)30 Downloads (Pure) -
N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide - a new kainate receptor selective antagonist and analgesic: Synthesis, X-ray crystallography, structure-affinity relationships, in vitro and in vivo pharmacology
Møllerud, S., Hansen, R. B., Pallesen, J. S., Temperini, P., Pasini, D., Bornholdt, J., Nielsen, B., Mamedova, E., Chalupnik, P., Paternain, A. V., Lerma, J., Del Castillo, M. D., Andreasen, J. T., Frydenvang, K., Kastrup, J. S., Johansen, T. N. & Pickering, D. S., 2019, In: ACS Chemical Neuroscience. 10, p. 4685-4695 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships and in vitro Pharmacology
Pallesen, J. S., Møllerud, S., Frydenvang, K. A., Pickering, D. S., Bornholt, J., Nielsen, B., Pasini, D., Han, L., Marconi, L., Kastrup, J. S. J. & Johansen, T. N., 20 Mar 2019, In: A C S Chemical Neuroscience. 10, p. 1841-1853 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands
Szymańska, E., Chałupnik, P., Johansen, T. N., Nielsen, B., Cuñado Moral, A. M., Pickering, D. S. & Kieć-Kononowicz, K., 1 Dec 2017, In: Chemical Biology & Drug Design. 90, p. 1271-1281 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors
Szymańska, E., Nielsen, B., Johansen, T. N., Cuñado Moral, A. M., Pickering, D. S., Szczepańska, K., Mickowska, A. & Kieć-Kononowicz, K., 2017, In: European Journal of Medicinal Chemistry. 138, p. 874-883 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
5 Citations (Scopus)
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Patientcentreret klinisk farmaci workshop
Lotte Stig Nørgaard (Participant), Tommy Nørskov Johansen (Member of organizing or programme committee), Charlotte Vermehren (Member of organizing or programme committee) & Johanne Mølby Hansen (Member of organizing or programme committee)
4 Apr 2024Activity: Participating in an event - types › Organisation of and participation in conference
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PCKF workshop
Johanne Mølby Hansen (Organizer), Lotte Stig Nørgaard (Organizer), Charlotte Vermehren (Organizer) & Tommy Nørskov Johansen (Organizer)
2 Mar 2023Activity: Participating in an event - types › Organisation of and participation in conference
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Stereochemistry and drug discovery
Tommy Nørskov Johansen (Lecturer)
1 Feb 2007Activity: Talk or presentation types › Lecture and oral contribution