Torben Hansen

Search results

• 2024

  A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

  de Vries, P. S., Reventun, P., Brown, M. R., Heath, A. S., Huffman, J. E., Le, N. Q., Bebo, A., Brody, J. A., Temprano-Sagrera, G., Raffield, L. M., Ozel, A. B., Thibord, F., Jain, D., Lewis, J. P., Rodriguez, B. A. T., Pankratz, N., Taylor, K. D., Polasek, O., Chen, M. H., Yanek, L. R. & 32 others, Carrasquilla, G. D., Marioni, R. E., Kleber, M. E., Trégouët, D. A., Yao, J., Li-Gao, R., Joshi, P. K., Trompet, S., Martinez-Perez, A., Ghanbari, M., Howard, T. E., Reiner, A. P., Arvanitis, M., Ryan, K. A., Bartz, T. M., Rudan, I., Faraday, N., Linneberg, A., Ekunwe, L., Davies, G., Delgado, G. E., Hansen, T., Chen, W. M., Jackson, R., Liu, Y., Loos, R. J. F., Rao, D. C., Wang, L., Nielsen, J. B., Kilpeläinen, T. O., Trans-Omics for Precision Medicine (TOPMed) program & the INVENT consortium, 2024, In: Blood. 143, 18, p. 1845-1855

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  2 Citations (Scopus)

• Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance

  Stinson, S. E., Fernández de Retana Alzola, I., Hovendal, E. D. B., Lund, M. A. V., Fonvig, C. E., Holm, L. A., Jonsson, A. E., Frithioff-Bøjsøe, C., Christiansen, M., Pedersen, O., Ängquist, L., Sørensen, T. I. A., Holst, J. J., Hartmann, B., Holm, J-C. & Hansen, T., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 6, p. 1590-1600 11 p.

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• Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans

  Lin, L., Andersen, M. K., Stæger, F. F., Li, Z., Hanghøj, K., Linneberg, A., Grarup, N., Jørgensen, M. E., Hansen, T., Moltke, I. & Albrechtsen, A., 2024, In: Genome Medicine. 16, 14 p., 71.

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• Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

  Kizilkaya, H. S., Sørensen, K. V., Madsen, J. S., Lindquist, P., Douros, J. D., Bork-Jensen, J., Berghella, A., Gerlach, P. A., Gasbjerg, L. S., Mokrosiński, J., Mowery, S. A., Knerr, P. J., Finan, B., Campbell, J. E., D’Alessio, D. A., Perez-Tilve, D., Faas, F., Mathiasen, S., Rungby, J., Sørensen, H. T. & 15 others, Vaag, A., Nielsen, J. S., Holm, J. C., Lauenborg, J., Damm, P., Pedersen, O., Linneberg, A., Hartmann, B., Holst, J. J., Hansen, T., Wright, S. C., Lauschke, V. M., Grarup, N., Hauser, A. S. & Rosenkilde, M. M., 2024, In: Nature Metabolism. 6, p. 1268–1281

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• Characterization of the gut bacterial and viral microbiota in latent autoimmune diabetes in adults

  Poulsen, C. S., Hesse, D., Fernandes, G. R., Hansen, T. H., Kern, T., Linneberg, A., Van Espen, L., Jørgensen, T., Nielsen, T., Alibegovic, A. C., Matthijnssens, J., Pedersen, O., Vestergaard, H., Hansen, T. & Andersen, M. K., 2024, In: Scientific Reports. 14, 1, 11 p., 8315.

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• Clinical effects of SGLT2 inhibitors in seven persons with HNF1A-MODY (MODY3)

  Maagensen, H., Hædersdal, S., Krogh, J., Hansen, T., Knop, F. K., Thuesen, A. C. B. & Vilsbøll, T., 2024, In: Diabetic Medicine. 41, 10, 4 p., e15387.

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• Depletion of TBC1D4 Improves the Metabolic Exercise Response by Overcoming Genetically Induced Peripheral Insulin Resistance

  Springer, C., Binsch, C., Weide, D., Toska, L., Cremer, A. L., Backes, H., Scheel, A. K., Espelage, L., Kotzka, J., Sill, S., Kurowski, A., Kim, D., Karpinski, S., Schnurr, T. M., Hansen, T., Hartwig, S., Lehr, S., Cames, S., Bruning, J. C., Lienhard, M. & 5 others, Herwig, R., Borno, S., Timmermann, B., Al-Hasani, H. & Chadt, A., 2024, In: Diabetes. 73, 7, p. 1058-1071 14 p.

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  2 Citations (Scopus)

• Distinct genetic signals at the FGF21 locus complicate studies of FGF21's role in diet regulation using human cohort data

  Ramne, S., García-Ureña, M., Gillum, M. P., Ängquist, L., Hansen, T., Merino, J. & Grarup, N., 2024, In: Molecular Metabolism. 90, 10 p., 102049.

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• Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

  Takele, W. W., Vesco, K. K., Josefson, J. L., Redman, L. M., Hannah, W., Bonham, M. P., Chen, M., Chivers, S. C., Fawcett, A. J., Grieger, J. A., Habibi, N., Leung, G. K. W., Liu, K., Mekonnen, E. G., Pathirana, M., Quinteros, A., Taylor, R., Ukke, G. G., Zhou, S. J., Franks, P. W. & 31 others, Rich, S. S., Wagner, R., Vilsbøll, T., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M., Redondo, M. J., Pratley, R. E., Pop-Busui, R., Pollin, T. I., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Murphy, R., Loos, R. J. F., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 15 p., 75.

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• Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology

  Madsen, A. L., Bonàs-Guarch, S., Gheibi, S., Prasad, R., Vangipurapu, J., Ahuja, V., Cataldo, L. R., Dwivedi, O., Hatem, G., Atla, G., Guindo-Martínez, M., Jørgensen, A. M., Jonsson, A. E., Miguel-Escalada, I., Hassan, S., Linneberg, A., Ahluwalia, T. S., Drivsholm, T., Pedersen, O., Sørensen, T. I. A. & 15 others, Astrup, A., Witte, D., Damm, P., Clausen, T. D., Mathiesen, E., Pers, T. H., Loos, R. J. F., Hakaste, L., Fex, M., Grarup, N., Tuomi, T., Laakso, M., Mulder, H., Ferrer, J. & Hansen, T., 2024, In: Nature Metabolism. 6, 10, p. 1897-1912 39 p.

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• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

  Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B. & 31 others, Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J-J., Pan, I., Taliun, D., Parra, E. J., Grarup, N., Chen, W-M., Bork-Jensen, J., Islam, M. T., Jørgensen, T., Linneberg, A., Witte, D. R., Lind, L., Hansen, T., Pedersen, O., Loos, R. J. F. & VA Million Veteran Program, 2024, In: Nature. 627, 8003, p. 347-357 11 p.

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• Genetic underpinnings of fasting and oral glucose-stimulated based insulin sensitivity indices

  Suleman, S., Madsen, A. L., Ängquist, L. H., Schubert, M., Linneberg, A., Loos, R. J. F., Hansen, T. & Grarup, N., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 11, p. 2754–2763 10 p.

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• Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health

  Stankevic, E., Kern, T., Borisevich, D., Poulsen, C. S., Madsen, A. L., Hansen, T. H., Jonsson, A., Schubert, M., Nygaard, N., Nielsen, T., Belstrøm, D., Ahluwalia, T. S., Witte, D. R., Grarup, N., Arumugam, M., Pedersen, O. & Hansen, T., 2024, In: Scientific Reports. 14, 11 p., 14738.

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• Genome-wide association study of preserved ratio impaired spirometry (PRISm)

  Higbee, D. H., Lirio, A., Hamilton, F., Granell, R., Wyss, A. B., London, S. J., Bartz, T. M., Gharib, S. A., Cho, M. H., Wan, E., Silverman, E., Crapo, J. D., Lominchar, J. V. T., Hansen, T., Grarup, N., Dantoft, T., Kårhus, L., Linneberg, A., O'Connor, G. T., Dupuis, J. & 25 others, Xu, H., De Vries, M. M., Hu, X., Rich, S. S., Barr, R. G., Manichaikul, A., Wijnant, S. R. A., Brusselle, G. G., Lahousse, L., Li, X., Hernández Cordero, A. I., Obeidat, M., Sin, D. D., Harris, S. E., Redmond, P., Taylor, A. M., Cox, S. R., Williams, A. T., Shrine, N., John, C., Guyatt, A. L., Hall, I. P., Davey Smith, G., Tobin, M. D. & Dodd, J. W., 2024, In: European Respiratory Journal. 63, 12 p.

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• Gut heavy metal and antibiotic resistome of humans living in the high Arctic

  Hauptmann, A. L., Johansen, J., Stæger, F. F., Nielsen, D. S., Mulvad, G., Hanghøj, K., Rasmussen, S., Hansen, T. & Albrechtsen, A., 2024, In: Frontiers in Microbiology. 15, 15 p., 1493803.

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• GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

  Senftleber, N. K., Andersen, M. K., Jørsboe, E., Stæger, F. F., Nøhr, A. K., Garcia-Erill, G., Meisner, J., Santander, C. G., Balboa, R. F., Gilly, A., Bjerregaard, P., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Moltke, I., Hansen, T. & Albrechtsen, A., 2024, In: European Journal of Human Genetics. 32, p. 215–223 9 p.

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• Healthcare Burden in Greenland of Gastrointestinal Symptoms in Adults with Inherited Loss of Sucrase-Isomaltase Function

  Andersen, K., Hansen, T., Jørgensen, M. E. & Senftleber, N., 2024, In: Application of Clinical Genetics. 17, p. 15-21 7 p.

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• Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents

  Kløve, S., Stinson, S. E., Romme, F. O., Butt, J., Graversen, K. B., Lund, M. A. V., Fonvig, C. E., Waterboer, T., Perez-Perez, G. I., Hansen, T., Holm, J-C. & Andersen, S. B., 2024, In: BMC Medicine. 22, 12 p., 379.

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• Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease

  Israelsen, M., Alvarez-Silva, C., Madsen, B. S., Hansen, C. D., Torp, N. C., Johansen, S., Hansen, J. K., Prier Lindvig, K., Insonere, J., Riviere, V., Juel, H. B., Brejnrod, A., Jensen, L. J., Thiele, M., Lelouvier, B., Hansen, T., Arumugam, M. & Krag, A., 2024, In: Gut. 73, 6, p. 1041-1044 gutjnl-2023-330360.

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• Increasing prevalence of galactose-α-1,3-galactose sensitization in the Danish general adult population

  Leth-Møller, K. B., van Hage, M., Apostolovic, D., Sørensen, J. A., Vestergaard, C., Madsen, F., Kjær, L. J., Hansen, T., Jonsson, A., Thomsen, S. F. & Linneberg, A., 2024, (E-pub ahead of print) In: Allergy.

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• Infections increase the risk of decompensation and death in patients with early alcohol-related liver disease

  Johansen, S., Langkjær, S., Rasmussen, D. N., Israelsen, M., Torp, N., Lindvig, K., Kjærgaard, M., Hansen, J. K., Hansen, C. D., Thorhauge, K., Andersen, P., Detlefsen, S., Juel, H. B., Justesen, U. S., Hansen, T., Krag, A., Thiele, M., GALAXY and MicrobLiver consortia & MicrobLiver Consortium, 2024, In: JHEP Reports. 6, 4, 10 p., 101016.

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• Interaction of genetic risk and lifestyle on the incidence of atrial fibrillation

  Frederiksen, T. C., Christiansen, M. K., Benjamin, E. J., Overvad, K., Olsen, A., Andersen, M. K., Hansen, T., Grarup, N., Jensen, H. K. & Dahm, C. C., 2024, In: Heart. 110, p. :644–649

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• Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

  ADA/EASD PMDI, Merino, J., Thuesen, A. C. B., Andersen, M. K., Clemmensen, C., Hansen, T., Nakabuye, M., Loos, R. J. F., Guasch-Ferré, M. & Vilsbøll, T., 2024, In: Communications Medicine. 4, 1, 8 p., 66.

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• Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

  Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, K. S., Kessing, L. V., Handgaard, L. J., Thørner, L. W., Didriksen, M., Nyegaard, M., Grarup, N., Ødum, N., Johansson, P. I., Jennum, P., Frikke-Schmidt, R., Berger, S. S., Brunak, S., Jacobsen, S., Hansen, T. F., Lundquist, T. K., Hansen, T., Sørensen, T. L., Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, H., Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, O. B., Ostrowski, S. R. & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

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• Lipid profiling identifies modifiable signatures of cardiometabolic risk in children and adolescents with obesity

  Huang, Y., Sulek, K., Stinson, S. E., Holm, L. A., Kim, M., Trost, K., Hooshmand, K., Lund, M. A. V., Fonvig, C. E., Juel, H. B., Nielsen, T., Ängquist, L., Rossing, P., Thiele, M., Krag, A., Holm, J. C., Legido-Quigley, C. & Hansen, T., 2024, (Accepted/In press) In: Nature Medicine.

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• Low birthweight in patients with type 2 diabetes is associated with elevated risk of cardiovascular events and mortality

  Hansen, A. L., Brøns, C., Engelhard, L. M., Andersen, M. K., Hansen, T., Nielsen, J. S., Vestergaard, P., Højlund, K., Jessen, N., Olsen, M. H., Sørensen, H. T., Thomsen, R. W. & Vaag, A., 2024, In: Diabetologia. 67, p. 1616–1629

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• Low-grade inflammation in persons with recently diagnosed type 2 diabetes: The role of abdominal adiposity and putative mediators

  Domazet, S. L., Olesen, T. B., Stidsen, J. V., Svensson, C. K., Nielsen, J. S., Thomsen, R. W., Jessen, N., Vestergaard, P., Andersen, M. K., Hansen, T., Brøns, C., Jensen, V. H., Vaag, A. A., Olsen, M. H. & Højlund, K., 2024, In: Diabetes, Obesity and Metabolism. 26, 6, p. 2092-2101

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• Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

  Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, C., Eriksson, J. G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, N., Gunjača, I., Hansen, T., Harding, B. N., Harris, S. E., Haunsø, S., Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, J. K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, A., Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, C., Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, O., Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, M. S., Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, T. I. A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A. & Medici, M., 2024, In: Nature Communications. 15, 1, 18 p., 888.

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• NK2R control of energy expenditure and feeding to treat metabolic diseases

  Sass, F., Ma, T., Ekberg, J. H., Kirigiti, M., Ureña, M. G., Dollet, L., Brown, J. M., Basse, A. L., Yacawych, W. T., Burm, H. B., Andersen, M. K., Nielsen, T. S., Tomlinson, A. J., Dmytiyeva, O., Christensen, D. P., Bader, L., Vo, C. T., Wang, Y., Rausch, D. M., Kristensen, C. K. & 27 others, Gestal-Mato, M., In het Panhuis, W., Sjøberg, K. A., Kernodle, S., Petersen, J. E., Pavlovskyi, A., Sandhu, M., Moltke, I., Jørgensen, M. E., Albrechtsen, A., Grarup, N., Babu, M. M., Rensen, P. C. N., Kooijman, S., Seeley, R. J., Worthmann, A., Heeren, J., Pers, T. H., Hansen, T., Gustafsson, M. B. F., Tang-Christensen, M., Kilpeläinen, T. O., Myers, M. G., Kievit, P., Schwartz, T. W., Hansen, J. B. & Gerhart-Hines, Z., 2024, In: Nature. 635, 8040, p. 987–1000 37 p.

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• Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases

  Thiele, M., Villesen, I. F., Niu, L., Johansen, S., Sulek, K., Nishijima, S., Espen, L. V., Keller, M., Israelsen, M., Suvitaival, T., Zawadzki, A. D., Juel, H. B., Brol, M. J., Stinson, S. E., Huang, Y., Silva, M. C. A., Kuhn, M., Anastasiadou, E., Leeming, D. J., Karsdal, M. & 12 others, Matthijnssens, J., Arumugam, M., Dalgaard, L. T., Legido-Quigley, C., Mann, M., Trebicka, J., Bork, P., Jensen, L. J., Hansen, T., Krag, A., MicrobLiver Consortium & GALAXY Consortium, 2024, In: Journal of Hepatology. 81, 2, p. 345-359

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• Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome

  Zhu, J., Eliasen, A. U., Aris, I. M., Stinson, S. E., Holm, J-C., Hansen, T., Hivert, M-F., Bønnelykke, K., Salem, R. M., Hirschhorn, J. N. & Chan, Y-M., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 2, p. 380-388

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• Precision stratification of prognostic risk factors associated with outcomes in gestational diabetes mellitus: a systematic review

  Semnani-Azad, Z., Gaillard, R., Hughes, A. E., Boyle, K. E., Tobias, D. K., Perng, W., Vilsbøll, T., Loos, R. J. F., Njølstad, P. R., Nakabuye, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 14 p., 9.

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• Precision treatment of beta-cell monogenic diabetes: a systematic review

  Naylor, R. N., Patel, K. A., Kettunen, J. L. T., Männistö, J. M. E., Støy, J., Beltrand, J., Polak, M., Franks, P. W., Rich, S. S., Wagner, R., Vilsbøll, T., Vesco, K. K., Udler, M. S., Tuomi, T., Sweeting, A., Sims, E. K., Sherr, J. L., Semple, R. K., Reynolds, R. M., Redondo, M. J. & 31 others, Redman, L. M., Pratley, R. E., Pop-Busui, R., Pollin, T. I., Perng, W., Pearson, E. R., Ozanne, S. E., Owen, K. R., Oram, R., Murphy, R., Mohan, V., Misra, S., Meigs, J. B., Mathioudakis, N., Mathieu, C., Ma, R. C. W., Loos, R. J. F., Lim, S. S., Laffel, L. M., Kwak, S. H., Josefson, J. L., Nolan, J. J., Nakabuye, M., Ried-Larsen, M., Hansen, T., Guasch-Ferré, M., Clemmensen, C., Andersen, M. K., Thuesen, A. C. B., Merino, J. & ADA/EASD PMDI, 2024, In: Communications Medicine. 4, 1, 17 p., 145.

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• Protocol for a randomised, double-blinded, controlled trial of youth with childhood-onset obesity treated with semaglutide 2.4 mg/week: the RESETTLE trial

  Byberg, S., Holt, J., Sandsdal, R. M., Holm, L. A., Madsen, L. B., Christensen, B. J., Jensen, S. B. K., Hansen, T., Holm, J. C. & Torekov, S., 2024, In: BMJ Open. 14, 11, 10 p., e082446.

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• Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort

  Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, Hansen, T., Linneberg, A. & Vaag, A., 2024, In: BMJ Open. 14, 1, 10 p., e078501.

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• Skeletal muscle from TBC1D4 p.Arg684Ter variant carriers is severely insulin resistant but exhibits normal metabolic responses during exercise

  Kristensen, J. M., Kjøbsted, R., Larsen, T. J., Carl, C. S., Hingst, J. R., Onslev, J., Birk, J. B., Thorup, A., Steenberg, D. E., Knudsen, J. R., Henriksen, N. S., Needham, E. J., Halling, J. F., Gudiksen, A., Rundsten, C. F., Hanghøj, K. E., Stinson, S. E., Hoier, B., Hansen, C. C., Jensen, T. E. & 11 others, Hellsten, Y., Pilegaard, H., Grarup, N., Olesen, J., Humphrey, S. J., James, D. E., Pedersen, M. L., Richter, E. A., Hansen, T., Jørgensen, M. E. & Wojtaszewski, J. F. P., 2024, (Accepted/In press) In: Nature Metabolism.

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• Temporal gut microbiota variability and association with dietary patterns: From the one-year observational Diet, Cancer, and Health - Next Generations MAX study

  Rostgaard-Hansen, A. L., Esberg, A., Dicksved, J., Hansen, T., Pelve, E., Brunius, C., Halkjær, J., Tjønneland, A., Johansson, I. & Landberg, R., 2024, In: American Journal of Clinical Nutrition. 119, 4, p. 1015-1026 12 p.

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• The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study

  Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A. & 26 others, McDonald, T. J., Kokkola, T., Rutters, F., Beulens, J., Muilwijk, M., Blom, M., Elders, P., Hansen, T. H., Fernandez-Tajes, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, O., Ruetten, H., Forgie, I., Holst, J. J., Thomsen, H. S., Ridderstråle, M., Bell, J. D., Adamski, J., Franks, P. W., Hansen, T., Holmes, E., Frost, G. & Pearson, E. R., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 9, p. e1697–e1707

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• The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project Cohort and Biobank from 2010 Through 2023 - A Cohort Profile Update

  Kristensen, F. P. B., Nicolaisen, S. K., Nielsen, J. S., Christensen, D. H., Højlund, K., Beck-Nielsen, H., Rungby, J., Friborg, S. G., Brandslund, I., Christiansen, J. S., Vestergaard, P., Jessen, N., Olsen, M. H., Andersen, M. K., Hansen, T., Brøns, C., Vaag, A., Thomsen, R. W. & Sørensen, H. T., 2024, In: Clinical Epidemiology. 16, p. 641-656 16 p.

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• The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk

  Stinson, S. E., Reim, P. K., Lund, M. A. V., Lausten-Thomsen, U., Holm, L. A., Huang, Y., Brøns, C., Vaag, A., Thiele, M., Krag, A., Fonvig, C. E., Grarup, N., Pedersen, O., Christiansen, M., Ängquist, L., Sørensen, T. I. A., Holm, J-C. & Hansen, T., 2024, In: EBioMedicine. 105, 12 p., 105205.

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• The Taste Liking Questionnaire (TasteLQ) – A tool for assessment of taste liking in the Danish population

  Haydar, S., Karlsson, C. C., Linneberg, A., Kårhus, L. L., Ängquist, L., Hansen, T., Bredie, W. & Grarup, N., 2024, In: Food Quality and Preference. 117, 12 p., 105176.

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• Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes

  Bradfield, J. P., Kember, R. L., Ulrich, A., Balkiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J-F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J-J., Íñiguez, C., Kobes, S., Leinonen, J. & 33 others, Lowry, E., Lyytikainen, L-P., Mahajan, A., Pitkänen, N., Schnurr, T. M., Have, C. T., Strachan, D. P., Thiering, E., Vogelezang, S., Wade, K. H., Wang, C. A., Wong, A., Holm, L. A., Chesi, A., Choong, C., Cruz, M., Elliott, P., Franks, S., Frithioff-Bøjsøe, C., Gauderman, W. J., Glessner, J. T., Gilsanz, V., Griesman, K., Hanson, R. L., Kaakinen, M., Kalkwarf, H., Kelly, A., Hansen, T., Holm, J-C., Sørensen, T. I. A., Grant, S. F. A., Cousminer, D. L. & Early Growth Genetics Consortium, 2024, In: Genome Biology. 25, 19 p., 22.

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• Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

  Huffman, J. E., Nicholas, J., Hahn, J., Heath, A. S., Raffield, L. M., Yanek, L. R., Brody, J. A., Thibord, F., Almasy, L., Bartz, T. M., Bielak, L. F., Bowler, R. P., Carrasquilla, G. D., Chasman, D. I., Chen, M-H., Emmert, D. B., Ghanbari, M., Haessler, J., Hottenga, J. J., Kleber, M. E. & 116 others, Le, N-Q., Lee, J., Lewis, J. P., Li-Gao, R., Luan, J., Malmberg, A. L., Mangino, M., Marioni, R., Martinez-Perez, A., Pankratz, N., Polasek, O., Richmond, A., Rodriguez, B. A. T., Rotter, J. I., Steri, M., Suchon, P., Trompet, S., Weiss, S., Zare, M., Auer, P. L., Cho, M., Christofidou, P., Davies, G., de Geus, E. J., Deleuze, J-F., Delgado, G. E., Ekunwe, L., Faraday, N., Gogele, M., Greinacher, A., Gao, H., Howard, T. E., Joshi, P. K., Kilpeläinen, T. O., Lahti, J., Linneberg, A., Naitza, S., Noordam, R., Vergés, F. P., Rich, S. S., Rosendaal, F. R., Rudan, I., Ryan, K. A., Souto, J. C. C., van Rooij, F. J. A., Wang, H., Zhao, W., Becker, L., Beswick, A., Brown, M. R., Cade, B., Campbell, H., Cho, K., Crapo, J., Curran, J., de Maat, M. P. M., Doyle, M. F., Elliott, P., Floyd, J. S., Fuchsberger, C., Grarup, N., Guo, X., Harris, S., Hou, L., Kolcic, I., Kooperberg, C., Menni, C., Nauck, M., O'Connell, J. R., Orru, V., Psaty, B. M., Räikkönen, K., Smith, J. A., Soria, J. M., Stott, D., van Hylckama Vlieg, A., Watkins, H., Willemsen, G., Wilson, P. W., Ben-Shlomo, Y., Blangero, J., Boomsma, D., Cox, S. R., Dehghan, A., Eriksson, J. G., Fiorillo, E., Fornage, M., Hansen, T., Hayward, C., Ikram, M. A., Jukema, J. W., Kardia, S., Lange, L., Maerz, W., Mathias, R., Mitchell, B. D., Mook-Kanamori, D. O., Morange, P-E., Pedersen, O., Pramstaller, P. P., Redline, S., Reiner, A. P., Ridker, P. M., Silverman, E. K., Spector, T. D., Volker, U., Wareham, N., Wilson, J., Yao, J., Tregouet, D-A., Johnson, A. D., Wolberg, A. S., de Vries, P. S., Sabater-Lleal, M., Morrison, A. & Smith, N. L., 2024, In: Blood. 144, 21, p. 2248–2265

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• 2023

  A comprehensive map of human glucokinase variant activity

  Gersing, S., Cagiada, M., Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, A., Gloyn, A. L., Hansen, T., Roth, F. P., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2023, In: Genome Biology. 24, 1, 23 p., 97.

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• Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction

  Thirion, F., Speyer, H., Hansen, T. H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Plaza Oñate, F., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S. K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O. & 3 others, Benros, M. E., Pedersen, O. & Ehrlich, S. D., 2023, In: Biological Psychiatry Global Open Science. 3, 2, p. 283-291 9 p.

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• An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents

  Huang, Y., Stinson, S. E., Juel, H. B., Lund, M. A. V., Holm, L. A., Fonvig, C. E., Nielsen, T., Grarup, N., Pedersen, O., Christiansen, M., Chabanova, E., Thomsen, H. S., Krag, A., Stender, S., Holm, J-C. & Hansen, T., 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.

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• A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

  Thuesen, A. C. B., Stæger, F. F., Kaci, A., Solheim, M. H., Aukrust, I., Jørsboe, E., Santander, C. G., Andersen, M. K., Li, Z., Gilly, A., Stinson, S. E., Gjesing, A. P., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, N., Jørgensen, M. E., Zeggini, E., Bjørkhaug, L., Njølstad, P. R. & 3 others, Albrechtsen, A., Moltke, I. & Hansen, T., 2023, In: The Lancet Regional Health - Europe. 24, 12 p., 100529.

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• Binge drinking episode causes acute, specific alterations in systemic and hepatic inflammation-related markers

  Stankevic, E., Israelsen, M., Juel, H. B., Madsen, A. L., Ängquist, L., Aldiss, P. S. J., Torp, N., Johansen, S., Hansen, C. D., Hansen, J. K., Thorhauge, K. H., Lindvig, K. P., Madsen, B. S., Sulek, K., Legido-Quigley, C., Thiele, M. S., Krag, A. & Hansen, T., 2023, In: Liver International. 43, 12, p. 2680–2691 12 p.

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• Biomarkers reflecting pericellular fibrosis improve together with liver histology after bariatric surgery in early non-alcoholic fatty liver disease

  Lønsmann, I., Pedersen, J. S., Krag, A., Hansen, T., Karsdal, M., Julie Leeming, D., Juul Nielsen, M. & Bendtsen, F., 2023, In: Clinical Biochemistry. 113, p. 29-35 7 p.

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• Birthweight is associated with clinical characteristics in people with recently diagnosed type 2 diabetes

  Hansen, A. L., Thomsen, R. W., Brøns, C., Svane, H. M. L., Jensen, R. T., Andersen, M. K., Hansen, T., Nielsen, J. S., Vestergaard, P., Højlund, K., Jessen, N., Olsen, M. H., Sørensen, H. T. & Vaag, A. A., 2023, In: Diabetologia. 66, p. 1680-1692 13 p.

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