Trine Lisberg Toft

Research output

Research output per year 2013 2021 2022 2024 2024

• 584 Citations
• 28 Journal article
• 4 Review
• 1 Conference abstract in journal
• 1 Letter

Research output per year

Research output per year

Search results

• 2024

  Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration

  Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, T., Wardman, J. H., Jensen, C. A., Styrishave, B., MacAulay, N., Jensen, R. H. & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  30 Downloads (Pure)

• Aqp4a and Trpv4 mediate regulatory cell volume increase for swimming maintenance of marine fish spermatozoa

  Castro-Arnau, J., Chauvigné, F., Toft-Bertelsen, T. L., Finn, R. N., MacAulay, N. & Cerdà, J., 2024, In: Cellular and Molecular Life Sciences. 81, 1, 22 p., 285.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  4 Downloads (Pure)

• CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension

  Wardman, J. H., Andreassen, S. N., Toft-Bertelsen, T. L., Jensen, M. N., Wilhjelm, J. E., Styrishave, B., Hamann, S., Heegaard, S., Sinclair, A. J. & MacAulay, N., 2024, In: Fluids and Barriers of the CNS. 21, 1, 20 p., 10.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  16 Downloads (Pure)

• The CSF lipid profile in patients with probable idiopathic normal pressure hydrocephalus differs from control but does not differ between shunt responders and non-responders

  Toft-Bertelsen, T. L., Andreassen, S. N., Simonsen, A. H., Hasselbalch, S. G. & MacAulay, N., 2024, In: Brain Communications. 6, 6, 10 p., fcae388.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

• Toward New AQP4 Inhibitors: ORI-TRN-002

  Thormann, M., Traube, N., Yehia, N., Koestler, R., Galabova, G., MacAulay, N. & Toft-Bertelsen, T. L., 2024, In: International Journal of Molecular Sciences. 25, 2, 11 p., 924.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  16 Downloads (Pure)
• 2023

  Distinct Cerebrospinal Fluid Lipid Signature in Patients with Subarachnoid Hemorrhage-Induced Hydrocephalus

  Toft-Bertelsen, T. L., Andreassen, S. N., Rostgaard, N., Olsen, M. H., Norager, N. H., Capion, T., Juhler, M. & MacAulay, N., 2023, In: Biomedicines. 11, 9, 14 p., 2360.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  4 Citations (Scopus)

  14 Downloads (Pure)

• Dual function of the choroid plexus: Cerebrospinal fluid production and control of brain ion homeostasis

  MacAulay, N. & Toft-Bertelsen, T. L., 2023, In: Cell Calcium. 116, 9 p., 102797.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  17 Downloads (Pure)
• 2022

  Acetazolamide modulates intracranial pressure directly by its action on the cerebrospinal fluid secretion apparatus

  Barbuskaite, D., Ørnbo, E. K., Wardman, J. H., Toft-Bertelsen, T. L., Conti, E., Andreassen, S. N., Gerkau, N. J., Rose, C. R. & MacAulay, N., 2022, In: Fluids and Barriers of the CNS. 19, 1, p. 53 1 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  15 Citations (Scopus)

  20 Downloads (Pure)

• Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1

  Toft-Bertelsen, T. L., Barbuskaite, D., Heerfordt, E. K., Lolansen, S. D., Andreassen, S. N., Rostgaard, N., Olsen, M. H., Norager, N. H., Capion, T., Rath, M. F., Juhler, M. & MacAulay, N., 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p., 69.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  27 Citations (Scopus)

  19 Downloads (Pure)

• Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure

  Oernbo, E. K., Steffensen, A. B., Khamesi, P. R., Toft-Bertelsen, T. L., Barbuskaite, D., Vilhardt, F., Gerkau, N. J., Tritsaris, K., Simonsen, A. H., Lolansen, S. D., Andreassen, S. N., Hasselbalch, S. G., Zeuthen, T., Rose, C. R., Kurtcuoglu, V. & MacAulay, N., 2022, In: Fluids and Barriers of the CNS. 19, 1, 25 p., 65.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  23 Citations (Scopus)

  29 Downloads (Pure)

• Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

  Lolansen, S. D., Rostgaard, N., Barbuskaite, D., Capion, T., Olsen, M. H., Norager, N. H., Vilhardt, F., Andreassen, S. N., Toft-Bertelsen, T. L., Ye, F., Juhler, M., Keep, R. F. & MacAulay, N., 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 62.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  19 Downloads (Pure)

• Reply to: How Many SARS-CoV-2 "Viroporins" Are Really Ion Channels? [Inkl. Correction]

  Toft-Bertelsen, T. L., Jeppesen, M. G., Landbrug, A., Mujezinovic, A., Bentzen, B. H., Kledal, T. N. & Rosenkilde, M. M., 2022, In: Communications Biology . 5, 1, 1 p., 860.

  Research output: Contribution to journal › Letter › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  21 Downloads (Pure)

• The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion

  Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, T., Wardman, J., Jensen, C., Styrishave, B., MacAulay, N., Jensen, R. H. & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.

  Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

• Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

  Andreassen, S. N., Toft-Bertelsen, T. L., Wardman, J. H., Villadsen, R. & MacAulay, N., 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  20 Downloads (Pure)

• Viroporiners potentiale som lægemiddeltargets med fokus på SARS-CoV-2

  Translated title of the contribution: The antiviral targeting potential of viroporinsSund, J. D., Bollerup, S., Glamann, J. B., Vinten, C. A., Jensen, L. R., Toft-Bertelsen, T. L., Bentzen, B. H., Kledal, T. N., Weis, N. & Rosenkilde, M., 13 Jun 2022, In: Ugeskrift for Laeger. 184, 24, 8 p., V02220103.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  13 Downloads (Pure)
• 2021

  Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro

  Toft-Bertelsen, T. L., Jeppesen, M. G., Tzortzini, E., Xue, K., Giller, K., Becker, S., Mujezinovic, A., Bentzen, B. H., Andreas, L. B., Kolocouris, A., Kledal, T. N. & Rosenkilde, M. M., 2021, In: Communications Biology. 4, 10 p., 1347.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  35 Citations (Scopus)

  28 Downloads (Pure)

• Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

  Lakk, M., Hoffmann, G. F., Gorusupudi, A., Enyong, E., Lin, A., Bernstein, P. S., Toft-Bertelsen, T., MacAulay, N., Elliott, M. H. & Krizaj, D., 2021, In: Journal of Lipid Research. 62, 15 p., 100145.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

  15 Downloads (Pure)

• TRPing on Cell Swelling-TRPV4 Senses It

  Toft-Bertelsen, T. L. & MacAulay, N., 2021, In: Frontiers in Immunology. 12, 9 p., 730982.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  20 Citations (Scopus)

  16 Downloads (Pure)

• TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel

  Toft-Bertelsen, T. L. & MacAulay, N., 2021, In: Cells. 10, 1, 16 p., 165.

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  41 Citations (Scopus)

  42 Downloads (Pure)
• 2020

  Clearance of activity-evoked K⁺ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor

  Toft-Bertelsen, T. L., Larsen, B. R., Christensen, S. K., Khandelia, H., Waagepetersen, H. S. & MacAulay, N., 2020, In: Glia. 69, 1, p. 28-41 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  29 Citations (Scopus)

  12 Downloads (Pure)

• Pannexin 1 activation and inhibition is permeant-selective

  Nielsen, B. S., Toft-Bertelsen, T. L., Lolansen, S. D., Anderson, C. L., Nielsen, M. S., Thompson, R. J. & MacAulay, N., 2020, In: The Journal of Physiology. 598, 2, p. 361-379 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  31 Citations (Scopus)

• The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission

  Wierda, K. D. B., Toft-Bertelsen, T. L., Gøtzsche, C. R., Pedersen, E., Korshunova, I., Nielsen, J., Bang, M. L., Kønig, A. B., Owczarek, S., Gjørlund, M. D., Schupp, M., Bock, E. & Sørensen, J. B., 2020, In: Scientific Reports. 10, 1, 15 p., 18041.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  20 Downloads (Pure)
• 2019

  Evaluating the involvement of cerebral microvascular endothelial Na⁺/K⁺-ATPase and Na⁺-K⁺-2Cl^- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration

  Lykke, K., Assentoft, M., Hørlyck, S., Helms, H. C. C., Stoica, A., Toft-Bertelsen, T. L., Tritsaris, K., Vilhardt, F., Brodin, B. & MacAulay, N., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 3, p. 497-512

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  10 Citations (Scopus)

• Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain

  Toft-Bertelsen, T. L., Yarishkin, O., Redmon, S., Phuong, T. T. T., Krizaj, D. & MacAulay, N., 2019, In: Journal of Biological Chemistry. 294, 48, p. 18421-18434 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  32 Downloads (Pure)
• 2018

  A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance

  Berland, S., Toft-Bertelsen, T. L., Aukrust, I., Byska, J., Vaudel, M., Bindoff, L. A., MacAulay, N. & Houge, G., 2018, In: Cold Spring Harbor molecular case studies. 4, 1, 10 p., a002303.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  5 Citations (Scopus)

  127 Downloads (Pure)

• Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy: [Inkl. Corrigendum]

  Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Lykke, K., Toft-Bertelsen, T. L., Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, N., Kaila, K. & Löscher, W., 2018, In: Neuropharmacology. 143, p. 186-204 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  37 Citations (Scopus)

• Sensing and regulation of cell volume - we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?

  Toft-Bertelsen, T. L., Larsen, B. R. & MacAulay, N., 2018, In: Channels (Austin). 12, 1, p. 100-108

  Research output: Contribution to journal › Review › Research › peer-review

  Open Access

  File
  19 Citations (Scopus)

  141 Downloads (Pure)
• 2017

  When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor

  Toft-Bertelsen, T. L., Križaj, D. & MacAulay, N., 2017, In: Journal of Physiology. 595, 11, p. 3287-3302 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  55 Citations (Scopus)

• When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor

  Toft-Bertelsen, T. L., Križaj, D. & MacAulay, N., 1 Jun 2017, In: The Journal of Physiology. 595, 11, p. 3287-3302 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
• 2016

  Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis

  Landegren, N., Pourmousa Lindberg, M., Skov, J., Hallgren, Å., Eriksson, D., Lisberg Toft-Bertelsen, T., MacAulay, N., Hagforsen, E., Räisänen-Sokolowski, A., Saha, H., Nilsson, T., Nordmark, G., Ohlsson, S., Gustafsson, J., Husebye, E. S., Larsson, E., Anderson, M. S., Perheentupa, J., Rorsman, F., Fenton, R. A. & 1 others, Kämpe, O., Oct 2016, In: Journal of the American Society of Nephrology:JASN. 27, 10, p. 3220-3228

  Research output: Contribution to journal › Journal article › Research › peer-review
  17 Citations (Scopus)

• Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters

  Toft-Bertelsen, T. L., Ziomkiewicz, I., Houy, S., da Silva Pinheiro, P. C. & Sørensen, J. B., 1 Nov 2016, In: Molecular Biology of the Cell. 27, 21, p. 3329-3341 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  19 Citations (Scopus)

  546 Downloads (Pure)
• 2014

  Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23

  Weber, J. P., Toft-Bertelsen, T. L., Mohrmann, R., Delgado-Martinez, I. & Sørensen, J. B., 2014, In: PloS one. 9, 11, p. 1-22 22 p., e114033.

  Research output: Contribution to journal › Journal article › Research › peer-review
  45 Citations (Scopus)

• The SNARE protein vti1a functions in dense-core vesicle biogenesis

  Walter, A. M., Kurps, J., de Wit, H., Schöning, S., Toft-Bertelsen, T. L., Lauks, J., Ziomkiewicz, I., Weiss, A. N., Schulz, A., Fischer von Mollard, G., Verhage, M. & Sørensen, J. B., 5 Jun 2014, In: E M B O Journal. 33, p. 1681-1697 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  34 Citations (Scopus)
• 2013

  Developmental and Diurnal Expression of the Synaptosomal-Associated Protein 25 (Snap25) in the Rat Pineal Gland

  Karlsen, A. S., Rath, M. F., Rohde, K., Toft, T. & Møller, M., Jun 2013, In: Neurochemical Research. 38, 6, p. 1219-1228 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  8 Citations (Scopus)