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Tuomas Oskari Kilpeläinen

PhD

 https://orcid.org/0000-0002-8349-3028

  • Blegdamsvej 3B, Mærsk Tårnet, 8. sal

    2200 København N.

  • Source: Scopus
20072024

Research activity per year

Personal profile

Short presentation

Tuomas Kilpeläinen is an Associate Professor at the Novo Nordisk Foundation Center for Basic Metabolic Research (Denmark) and a Visiting Scientist at the Broad Institute of MIT and Harvard (USA). He completed his PhD at the University of Kuopio (Finland) and a 3-year postdoc at the University of Cambridge (UK). In 2015-2016, he was a Visiting Scientist and an Adjunct Assistant Professor at the Icahn School of Medicine at Mount Sinai (New York). Tuomas leads an inter-disciplinary research group that studies the genomics of obesity and metabolic health. His goal is to advance our understanding of obesity-related cardiometabolic disease by uncovering the mechanisms of action of genetic risk variants, particularly in adipose tissue.

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  • A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

    de Vries, P. S., Reventun, P., Brown, M. R., Heath, A. S., Huffman, J. E., Le, N. Q., Bebo, A., Brody, J. A., Temprano-Sagrera, G., Raffield, L. M., Ozel, A. B., Thibord, F., Jain, D., Lewis, J. P., Rodriguez, B. A. T., Pankratz, N., Taylor, K. D., Polasek, O., Chen, M. H., Yanek, L. R. & 32 others, Carrasquilla, G. D., Marioni, R. E., Kleber, M. E., Trégouët, D. A., Yao, J., Li-Gao, R., Joshi, P. K., Trompet, S., Martinez-Perez, A., Ghanbari, M., Howard, T. E., Reiner, A. P., Arvanitis, M., Ryan, K. A., Bartz, T. M., Rudan, I., Faraday, N., Linneberg, A., Ekunwe, L., Davies, G., Delgado, G. E., Hansen, T., Chen, W. M., Jackson, R., Liu, Y., Loos, R. J. F., Rao, D. C., Wang, L., Nielsen, J. B., Kilpeläinen, T. O., Trans-Omics for Precision Medicine (TOPMed) program & the INVENT consortium, 2024, In: Blood. 143, 18, p. 1845-1855

    Research output: Contribution to journal › Journal article › Research › peer-review

    2 Citations (Scopus)

  • Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease

    Carrasquilla, G. D., Ängquist, L., Sørensen, T. I. A., Kilpeläinen, T. O. & Loos, R. J. F., 2024, In: Diabetologia. 67, p. 864–873 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    2 Citations (Scopus)
    19 Downloads (Pure)

  • Estimating causality between smoking and abdominal obesity by Mendelian randomization

    Carrasquilla, G. D., García-Ureña, M., Romero-Lado, M. J. & Kilpeläinen, T. O., 2024, In: Addiction. 119, p. 1024-1034

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    7 Downloads (Pure)

  • Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

    Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, Madsen, K. L. & Clemmensen, C., 2024, In: Science Advances. 10, 9, 20 p., eadg2636.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    2 Citations (Scopus)
    38 Downloads (Pure)

  • Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

    Huffman, J. E., Nicholas, J., Hahn, J., Heath, A. S., Raffield, L. M., Yanek, L. R., Brody, J. A., Thibord, F., Almasy, L., Bartz, T. M., Bielak, L. F., Bowler, R. P., Carrasquilla, G. D., Chasman, D. I., Chen, M-H., Emmert, D. B., Ghanbari, M., Haessler, J., Hottenga, J. J., Kleber, M. E. & 116 others, Le, N-Q., Lee, J., Lewis, J. P., Li-Gao, R., Luan, J., Malmberg, A. L., Mangino, M., Marioni, R., Martinez-Perez, A., Pankratz, N., Polasek, O., Richmond, A., Rodriguez, B. A. T., Rotter, J. I., Steri, M., Suchon, P., Trompet, S., Weiss, S., Zare, M., Auer, P. L., Cho, M., Christofidou, P., Davies, G., de Geus, E. J., Deleuze, J-F., Delgado, G. E., Ekunwe, L., Faraday, N., Gogele, M., Greinacher, A., Gao, H., Howard, T. E., Joshi, P. K., Kilpeläinen, T. O., Lahti, J., Linneberg, A., Naitza, S., Noordam, R., Vergés, F. P., Rich, S. S., Rosendaal, F. R., Rudan, I., Ryan, K. A., Souto, J. C. C., van Rooij, F. J. A., Wang, H., Zhao, W., Becker, L., Beswick, A., Brown, M. R., Cade, B., Campbell, H., Cho, K., Crapo, J., Curran, J., de Maat, M. P. M., Doyle, M. F., Elliott, P., Floyd, J. S., Fuchsberger, C., Grarup, N., Guo, X., Harris, S., Hou, L., Kolcic, I., Kooperberg, C., Menni, C., Nauck, M., O'Connell, J. R., Orru, V., Psaty, B. M., Räikkönen, K., Smith, J. A., Soria, J. M., Stott, D., van Hylckama Vlieg, A., Watkins, H., Willemsen, G., Wilson, P. W., Ben-Shlomo, Y., Blangero, J., Boomsma, D., Cox, S. R., Dehghan, A., Eriksson, J. G., Fiorillo, E., Fornage, M., Hansen, T., Hayward, C., Ikram, M. A., Jukema, J. W., Kardia, S., Lange, L., Maerz, W., Mathias, R., Mitchell, B. D., Mook-Kanamori, D. O., Morange, P-E., Pedersen, O., Pramstaller, P. P., Redline, S., Reiner, A. P., Ridker, P. M., Silverman, E. K., Spector, T. D., Volker, U., Wareham, N., Wilson, J., Yao, J., Tregouet, D-A., Johnson, A. D., Wolberg, A. S., de Vries, P. S., Sabater-Lleal, M., Morrison, A. & Smith, N. L., 3 Sep 2024, (E-pub ahead of print) In: Blood.

    Research output: Contribution to journal › Journal article › Research › peer-review

    1 Citation (Scopus)

  • Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss

    Christiansen, M. R., Kilpelöainen, T. O. & McCaffery, J. M., 2023, In: Diabetes. 72, 10, p. 1424-1432 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    5 Citations (Scopus)
    3 Downloads (Pure)

  • Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

    de las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C. Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A., Kolčić, I. & 178 others, Lim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F. C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L. P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y. D. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C. K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs, D. R., Kavousi, M., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O’Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polašek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y. X., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Völzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C. T., Morrison, A. C., Rotter, J. I. & Fornage, M., 2023, In: Frontiers in Genetics. 14, 16 p., 1235337.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    9 Downloads (Pure)

  • Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

    Drag, M. H., Debes, K. P., Franck, C. S., Flethøj, M., Lyhne, M. K., Møller, J. E., Ludvigsen, T. P., Jespersen, T., Olsen, L. H. & Kilpeläinen, T. O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
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    1 Citation (Scopus)
    42 Downloads (Pure)
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