Research output per year
Research output per year
Personal profile
Short presentation
Common chromosomal fragile sites (CFSs) are regions of the genome that are highly unstable. CFSs host extremely large genes. The aim of my research is to understand why extremely large genes cause genomic instability and how mutations arise at CFSs. Moreover, our goal is to unravel potential biological functions of CFSs.
Keywords
- Faculty of Science
- Chromosomal Fragile Sites
- DNA repair
- Genome Stability
- Molecular genetics
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A mutational atlas for Parkin proteostasis
Clausen, L., Voutsinos, V., Cagiada, M., Johansson, K. E., Grønbæk-Thygesen, M., Nariya, S., Powell, R. L., Have, M. K. N., Oestergaard, V. H., Stein, A., Fowler, D. M., Lindorff-Larsen, K. & Hartmann-Petersen, R., 2024, In: Nature Communications. 15, 1, 17 p., 1541.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)17 Downloads (Pure) -
Emerging roles of the CIP2A–TopBP1 complex in genome integrity
Ummethum, H., Li, J., Lisby, M. & Oestergaard, VH., 2023, In: NAR Cancer. 5, 4, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)34 Downloads (Pure) -
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
Ambjorn, S. M., Duxin, J. P., Hertz, E. P. T., Nasa, I., Duro, J., Kruse, T., Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Oestergaard, V. H., Lisby, M. & Nilsson, J., 2021, In: Nature Communications. 12, 1, 11 p., 5748.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Citations (Scopus)102 Downloads (Pure) -
Functions of TopBP1 in preserving genome integrity during mitosis
Bagge, J., Oestergaard, V. H. & Lisby, M., 2021, In: Seminars in Cell and Developmental Biology. 113, p. 57-64 8 p.Research output: Contribution to journal › Review › Research › peer-review
21 Citations (Scopus) -
Large Intronic Deletion of the Fragile Site Gene PRKN Dramatically Lowers Its Fragility Without Impacting Gene Expression
Munk, S. H. N., Voutsinos, V. & Oestergaard, V. H., 2021, In: Frontiers in Genetics. 12, 9 p., 695172.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)58 Downloads (Pure) -
A distinct role for recombination repair factors in an early cellular response to transcription-replication conflicts
Shao, X., Joergensen, A. M., Howlett, N. G., Lisby, M. & Oestergaard, V. H., 2020, In: Nucleic Acids Research. 48, 10, p. 5467-5484 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile23 Citations (Scopus)144 Downloads (Pure) -
The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, S., Simonsen, A. K. W., Viswalingam, K. S., Gonzalez, L., Hickson, I. D., Oestergaard, V. H., Mankouri, H. W., Sung, P. & Lisby, M., 2020, In: Cell Reports. 32, 1, 25 p., 107849.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)122 Downloads (Pure) -
Common Chromosomal Fragile Sites - Conserved Failure Stories
Voutsinos, V., Munk, S. H. N. & Østergaard, V. H., 2018, In: Genes. 9, 12, p. 1-16 580.Research output: Contribution to journal › Review › Research › peer-review
Open AccessFile18 Citations (Scopus)120 Downloads (Pure)