Research output per year
Research output per year
Personal profile
Short presentation
My current research focuses on how mitochondrial dysfunction and impaired mitophagy contribute to brain aging and neurodegenerative diseases, including Alzheimer’s disease. We use patient-derived cells and iPSC-differentiated brain cells for disease modeling and drug screening, with the goal of uncovering underlying mechanisms and identifying promising therapeutic targets for neurodegenerative disorders.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Interactions between rare variants in DNA repair genes and cardiometabolic risk explain more variability in cognitive function
Cherbuin, N., Camargo Tavares, L., Fraser, M. A., Li, Y., Navarro, C., Walsh, E. I., Andrews, S. J., Burns, R. A., Brüstle, A. & Juel Rasmussen, L., 2026, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Editorial: Targeting the aging mitochondria: mechanisms, methods, and therapeutic strategies
Li, Z., Palikaras, K., Li, Y. & Bohr, V. A., 2025, In: Frontiers in Aging Neuroscience. 17, 3 p., 1591288.Research output: Contribution to journal › Editorial › Research › peer-review
Open AccessFile51 Downloads (Pure) -
Functional analysis of pathological mutations in DNA topoisomerase 3A
Wang, Y., Kaiser, S., Martin-Gonzalez, J., Li, Y., Rasmussen, L. J., Lopez-Contreras, A. J., Bizard, A. H. & Hickson, I. D., 2025, In: Cell Reports. 44, 6, 23 p., 115764.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Citations (Scopus)53 Downloads (Pure) -
FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species
Song, J., Li, Z., Zhou, L., Chen, X., Sew, W. Q. G., Herranz, H., Ye, Z., Olsen, J. V., Li, Y., Nygaard, M., Christensen, K., Tong, X., Bohr, V. A., Rasmussen, L. J. & Dai, F., 2024, In: Nature Communications. 15, 1, 18 p., 7144.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile44 Citations (Scopus)138 Downloads (Pure) -
Human fibroblasts from sporadic Alzheimer's disease (AD) patients show mitochondrial alterations and lysosome dysfunction
Li, Y., Li, Z., Grillo, E., Desler, C., Navarro, C., Bohr, V. A., Berliocchi, L. & Rasmussen, L. J., 2024, In: Free Radical Biology and Medicine. 222, p. 569-578 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Citations (Scopus)105 Downloads (Pure) -
Interactions between mitochondrial dysfunction and other hallmarks of aging: Paving a path toward interventions that promote healthy old age
Li, Y., Berliocchi, L., Li, Z. & Rasmussen, L. J., 2024, In: Aging Cell. 23, 1, 12 p., e13942.Research output: Contribution to journal › Review › peer-review
Open AccessFile45 Citations (Scopus)139 Downloads (Pure) -
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Y., Orduña Dolado, A., Li, Z., Andersson, R., Berliocchi, L. & Rasmussen, L. J., 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)139 Downloads (Pure) -
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, S., Li, Z., Li, Y., Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, V. A., Desler, C., Naviaux, R. K. & Rasmussen, L. J., 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)149 Downloads (Pure)