Zach Gerhart-Hines

Zach Gerhart-Hines

Ph.D. Biochemistry-Cellular and Molecular Biology

  • Blegdamsvej 3B, Mærsk Tårnet, 6. sal

    2200 København N.

  • Source: Scopus
20062024

Research activity per year

Personal profile

Current research

Signals or cues from the environment, diet, circadian clock, and other organs exert substantial control over the plasticity and function of adipose tissue. The overarching goal of my group is to uncover how these diverse 'inputs' converge on adipocytes to uniquely shape adipose tissue biology and coordinate organismal energy metabolism. Specifically, we focus on identifying cell surface receptors, intracellular enzymes, and transporters that represent key regulatory nodes in influencing adipose tissue catabolism. By combining global gene, protein, metabolite, and lipid profiling with cutting-edge in vivo physiological phenotyping and pharmacological engineering, we believe we are ideally poised to make transformative breakthroughs in the basic understanding of adipose biology and to develop innovative strategies for counteracting metabolic disease.

Possible conflicts of interest

I am a co-founder of Embark Biotech ApS, a company developing therapeutics for the treatment of type 2 diabetes and obesity.

Education/Academic qualification

Biochemistry-Cellular and Molecular Biology, Ph.D., Johns Hopkins University

Award Date: 1 Mar 2011

Keywords

  • Metabolism
  • Insulin sensitivity
  • Adipose tissue
  • Energy Expenditure
  • Obesity
  • Diabetes
  • Mitochondria
  • G Protein-Coupled Receptors
  • Circadian Rhythm

Collaborations and top research areas from the last five years

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