Zach Gerhart-Hines

Search results

• 2024

  Mild Cold Stress at Ambient Temperature Elevates Muscle Calcium Cycling and Exercise Adaptations in Obese Female Mice

  Raun, S. H., Braun, J. L., Karavaeva, I., Henriquez-Olguín, C., Ali, M. S., Møller, L. L. V., Gerhart-Hines, Z., Fajardo, V. A., Richter, E. A. & Sylow, L., 2024, In: Endocrinology (United States). 165, 10, bqae102.

  Research output: Contribution to journal › Journal article › Research › peer-review

• NK2R control of energy expenditure and feeding to treat metabolic diseases

  Sass, F., Ma, T., Ekberg, J. H., Kirigiti, M., Ureña, M. G., Dollet, L., Brown, J. M., Basse, A. L., Yacawych, W. T., Burm, H. B., Andersen, M. K., Nielsen, T. S., Tomlinson, A. J., Dmytiyeva, O., Christensen, D. P., Bader, L., Vo, C. T., Wang, Y., Rausch, D. M., Kristensen, C. K. & 27 others, Gestal-Mato, M., In het Panhuis, W., Sjøberg, K. A., Kernodle, S., Petersen, J. E., Pavlovskyi, A., Sandhu, M., Moltke, I., Jørgensen, M. E., Albrechtsen, A., Grarup, N., Babu, M. M., Rensen, P. C. N., Kooijman, S., Seeley, R. J., Worthmann, A., Heeren, J., Pers, T. H., Hansen, T., Gustafsson, M. B. F., Tang-Christensen, M., Kilpeläinen, T. O., Myers, M. G., Kievit, P., Schwartz, T. W., Hansen, J. B. & Gerhart-Hines, Z., 2024, In: Nature. 635, 8040, p. 987–1000 37 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  10 Downloads (Pure)
• 2023

  Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice

  Correia, C. M., Præstholm, S. M., Havelund, J. F., Pedersen, F. B., Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Z., Heeren, J., Brewer, J., Larsen, S., Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue

  Bager Christensen, I., Blom, I., Dohlmann, T. L., Finger, F., W Helge, J., Gerhart-Hines, Z., Dela, F. & Larsen, S., 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 10, p. e916-e922 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

• Full activation of thermogenesis in brown adipocytes requires Basigin action

  Rupar, K., Isidor, M. S., Argemi-Muntadas, L., Agueda-Oyarzabal, M., Plucińska, K., Brown, E. L., Mattanovich, M., Bossi, S., Tozzi, M., Tandio, D., Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, J. B., Gerhart-Hines, Z., Nielsen, S., Moritz, T. & Emanuelli, B., 2023, In: F E B S Journal. 290, 10, p. 2673-2691

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  2 Citations (Scopus)

  98 Downloads (Pure)

• Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

  Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Z. & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  28 Citations (Scopus)

  30 Downloads (Pure)

• NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

  Basse, A. L., Nielsen, K. N., Karavaeva, I., Ingerslev, L. R., Ma, T., Havelund, J. F., Nielsen, T. S., Frost, M., Peics, J., Dalbram, E., Dall, M., Zierath, J. R., Barrès, R., Færgeman, N. J., Treebak, J. T. & Gerhart-Hines, Z., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  12 Citations (Scopus)

  72 Downloads (Pure)

• Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

  Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, J. T., 2023, In: npj Aging. 9, 21 p., 7.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Citations (Scopus)

  40 Downloads (Pure)

• PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

  Backe, M. B., Andersen, R. C., Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, J. T., Hansen, J. B., Gerhart-hines, Z., Madsen, K. L. & Holst, B., 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  1 Citation (Scopus)

  33 Downloads (Pure)

• ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

  Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, A. H., Treebak, J. T., Olsen, J. V., Poulsen, S. S., Pownall, M. E., Jensen, B. A. H., Clemmensen, C., Gerhart-Hines, Z., Gatfield, D. & Bekker-Jensen, S., 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  31 Citations (Scopus)

  53 Downloads (Pure)

• The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

  Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, C., 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File
  28 Citations (Scopus)

• TNIK is a conserved regulator of glucose and lipid metabolism in obesity

  Pham, T. C. P., Dollet, L., Ali, M. S., Raun, S. H., Møller, L. L. V., Jafari, A., Ditzel, N., Andersen, N. R., Fritzen, A. M., Gerhart-Hines, Z., Kiens, B., Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, P., Nieminen, A. I., Richter, E. A., Havula, E. & Sylow, L., 2023, In: Science Advances. 9, 32, 18 p., eadf7119.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  7 Citations (Scopus)

  40 Downloads (Pure)
• 2022

  Fueling the fire of adipose thermogenesis

  Wolfrum, C. & Gerhart-Hines, Z., 2022, In: Science. 375, 6586, p. 1229-1231 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  38 Citations (Scopus)

  12 Downloads (Pure)

• Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

  Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Z., Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, A. E. B., Olsen, B. H., Hansen, T., Gluud, L. L., Madsbad, S., Larsen, S., Bendtsen, F. & Dela, F., 2022, In: Nature Communications. 13, 15 p., 2931.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  20 Citations (Scopus)

  37 Downloads (Pure)

• Lipolysis regulates major transcriptional programs in brown adipocytes

  Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, J. B., Gerhart-Hines, Z., Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  26 Citations (Scopus)

  60 Downloads (Pure)

• Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

  Snieckute, G., Genzor, A. V., Vind, A. C., Ryder, L., Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, F., Blasius, M., López, A. R., Brynjólfsdóttir, S. H., Andersen, K. L., Willis, A. E., Frankel, L. B., Poulsen, S. S., Gatfield, D., Gerhart-Hines, Z., Clemmensen, C. & Bekker-Jensen, S., 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  31 Citations (Scopus)

  53 Downloads (Pure)
• 2021

  Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake

  de Guia, R. M., Hassing, A. S., Ma, T., Plucinska, K., Holst, B., Gerhart-Hines, Z., Emanuelli, B. & Treebak, J. T., 2021, In: F A S E B Journal. 35, 5, e21450.

  Research output: Contribution to journal › Journal article › Research › peer-review
  3 Citations (Scopus)

• Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men

  Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, A. E., Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A-S., Berntsen, M., Loft, A., Kjaer, A., Gerhart-Hines, Z., Johannesen, H. H., Pedersen, B. K., Karstoft, K. & Scheele, C., 2021, In: Cell Reports Medicine. 2, 10, 23 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  36 Citations (Scopus)

  159 Downloads (Pure)

• Cold-induction of afadin in brown fat supports its thermogenic capacity

  Lundh, M., Altıntaş, A., Tozzi, M., Fabre, O., Ma, T., Shamsi, F., Gerhart-Hines, Z., Barrès, R., Tseng, Y-H. & Emanuelli, B., 2021, In: Scientific Reports. 11, 11 p., 9794.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  3 Citations (Scopus)

  46 Downloads (Pure)

• Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis

  Neess, D., Kruse, V., Marcher, A. B., Wæde, M. R., Vistisen, J., Møller, P. M., Petersen, R., Brewer, J. R., Ma, T., Colleluori, G., Severi, I., Cinti, S., Gerhart-Hines, Z., Mandrup, S. & Færgeman, N. J., 2021, In: Molecular Metabolism. 44, 11 p., 101144.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  46 Downloads (Pure)

• White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

  Rabiee, A., Plucińska, K., Isidor, M. S., Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda-Oyarzabal, M., Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, A., Barrès, R., Jensen, O. N., Gerhart-Hines, Z. & Emanuelli, B., 2021, In: Molecular Metabolism. 44, 17 p., 101137.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  14 Citations (Scopus)

  113 Downloads (Pure)
• 2020

  Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

  Husted, A. S., Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, T., Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Z., Calebiro, D., Dragsted, L. O. & Schwartz, T. W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  17 Citations (Scopus)

  69 Downloads (Pure)

• Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

  Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, S. D., Hansen, M. H., Høgh, R. I., Aldana, B. I., Desler, C., Rasmussen, L. J., Sustarsic, E. G., Gerhart-Hines, Z., Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, H. H., Andresen, L. & Skov, S., 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  11 Citations (Scopus)

  92 Downloads (Pure)

• Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus

  de Guia, R. M., Hassing, A. S., Skov, L. J., Ratner, C., Plucinska, K., Madsen, S., Diep, T. A., Dela Cruz, G. V., Trammell, S. A. J., Sustarsic, E. G., Emanuelli, B., Gillum, M. P., Gerhart-Hines, Z., Holst, B. & Treebak, J. T., 2020, In: Acta Physiologica. 228, 4

  Research output: Contribution to journal › Journal article › Research › peer-review
  22 Citations (Scopus)

• Housing temperature influences exercise training adaptations in mice

  Raun, S. H., Henriquez-Olguín, C., Karavaeva, I., Ali, M., Møller, L. L. V., Kot, W., Castro-Mejía, J. L., Nielsen, D. S., Gerhart-Hines, Z., Richter, E. A. & Sylow, L., 2020, In: Nature Communications. 11, 16 p., 1560.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  56 Citations (Scopus)

  152 Downloads (Pure)

• Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

  Khatib-Massalha, E., Bhattacharya, S., Massalha, H., Biram, A., Golan, K., Kollet, O., Kumari, A., Avemaria, F., Petrovich-Kopitman, E., Gur-Cohen, S., Itkin, T., Brandenburger, I., Spiegel, A., Shulman, Z., Gerhart-Hines, Z., Itzkovitz, S., Gunzer, M., Offermanns, S., Alon, R., Ariel, A. & 1 others, Lapidot, T., 2020, In: Nature Communications. 11, 1, 18 p., 3547.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  107 Citations (Scopus)

  37 Downloads (Pure)

• Role of Energy Excretion in Human Body Weight Regulation

  Lund, J., Gerhart-Hines, Z. & Clemmensen, C., 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  25 Citations (Scopus)

  60 Downloads (Pure)

• Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

  Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, J., Ingerslev, L. R., Fritzen, A. M., Carl, C. S., Lundsgaard, A., Frost, M., Ma, T., Schjerling, P., Gerhart-Hines, Z., Flamant, F., Gauthier, K., Larsen, S., Richter, E. A., Kiens, B. & Clemmensen, C., 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  24 Citations (Scopus)

  144 Downloads (Pure)
• 2019

  Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

  Lundh, M., Petersen, P. S., Isidor, M. S., Kazoka-Sørensen, D. N., Plucińska, K., Shamsi, F., Ørskov, C., Tozzi, M., Brown, E. L., Andersen, E., Ma, T., Müller, U. A., Barrès, R., Kristiansen, V. B., Gerhart-Hines, Z., Tseng, Y-H. & Emanuelli, B., 2019, In: EMBO Reports. 20, 8, e48216.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  14 Citations (Scopus)

• Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

  Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, M. & Scheele, C., 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  115 Citations (Scopus)
• 2018

  A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening

  van den Berg, R., Kooijman, S., Noordam, R., Ramkisoensing, A., Abreu-Vieira, G., Tambyrajah, L. L., Dijk, W., Ruppert, P., Mol, I. M., Kramar, B., Caputo, R., Puig, L. S., de Ruiter, E. M., Kroon, J., Hoekstra, M., van der Sluis, R. J., Meijer, O. C., Willems van Dijk, K., van Kerkhof, L. W. M., Christodoulides, C. & 8 others, Karpe, F., Gerhart-Hines, Z., Kersten, S., Meijer, J. H., Coomans, C. P., van Heemst, D., Biermasz, N. R. & Rensen, P. C. N., 2018, In: Cell Reports. 22, 13, p. 3521-3533 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  72 Citations (Scopus)

  318 Downloads (Pure)

• Brown fat: the biological furnace that could burn away obesity

  Lund, J., Peics, J. & Gerhart-Hines, Z., 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

  Research output: Contribution to journal › Journal article › Research

  File

• Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

  Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, A., Pedersen, O., Kiebish, M. A., Qvortrup, K., Han, X., Pedersen, B. K., Jastroch, M., Mandrup, S., Kjær, A., Gygi, S. P., Hansen, T., Gillum, M. P., Grarup, N., Emanuelli, B., Nielsen, S., Scheele, C., Tseng, Y-H., Færgeman, N. J. & Gerhart-Hines, Z., 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  110 Citations (Scopus)

  429 Downloads (Pure)

• Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism

  Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, F., Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Z., Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  62 Citations (Scopus)

  106 Downloads (Pure)

• Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

  Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Z., Brodin, P., Pereira, T., Berggren, P-O. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5

  Research output: Contribution to journal › Journal article › Research › peer-review
  207 Citations (Scopus)

• NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

  Nielsen, K. N., Peics, J., Ma, T., Karavaeva, I., Dall, M., Chubanava, S., Basse, A. L., Dmytriyeva, O., Treebak, J. T. & Gerhart-Hines, Z., May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  62 Citations (Scopus)

  326 Downloads (Pure)

• Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status

  Basse, A. L., Dalbram, E., Larsson, L., Gerhart-Hines, Z., Zierath, J. R. & Treebak, J. T., 2018, In: Frontiers in Physiology. 9, p. 1-12 12 p., 1198.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  33 Citations (Scopus)

  297 Downloads (Pure)
• 2017

  Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

  Emmett, M. J., Lim, H-W., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, T., Sims, C. A., Baur, J. A., Pei, L., Won, K-J., Seale, P., Gerhart-Hines, Z. & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  142 Citations (Scopus)
• 2015

  Rev-erbα and the circadian transcriptional regulation of metabolism.

  Gerhart-Hines, Z. & Lazar, M. A., 2015, In: Diabetes, Obesity and Metabolism Online. 17, S1, p. 12-16 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  29 Citations (Scopus)
• 2014

  Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor rev-erbα

  Jager, J., Timothy O'Brien, W., Manlove, J., Krizman, E. N., Fang, B., Gerhart-Hines, Z., Robinson, M. B., Klein, P. S. & Lazar, M. A., 2014, In: Molecular Endocrinology. 28, 4, p. 490-498 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  61 Citations (Scopus)

• Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

  Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Z., Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  181 Citations (Scopus)
• 2013

  Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex

  Lim, J. H., Gerhart-Hines, Z., Dominy, J. E., Lee, Y., Kim, S., Tabata, M., Xiang, Y. K. & Puigserver, P., 8 Mar 2013, In: Journal of Biological Chemistry. 288, 10, p. 7117-7126 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  173 Citations (Scopus)

• The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

  Gerhart-Hines, Z., Feng, D., Emmett, M. J., Everett, L. J., Loro, E., Briggs, E. R., Bugge, A. S., Hou, C., Ferrara, C., Seale, P., Pryma, D. A., Khurana, T. S. & Lazar, M. A., 2013, In: Nature. 503, 7476, p. 410-3 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  226 Citations (Scopus)
• 2012

  A metabolic prosurvival role for PML in breast cancer

  Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Z., Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  227 Citations (Scopus)
• 2011

  Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming

  Dominy, J. E., Gerhart-Hines, Z. & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  11 Citations (Scopus)

• The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD ⁺

  Gerhart-Hines, Z., Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  278 Citations (Scopus)
• 2009

  AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity

  Cantó, C., Gerhart-Hines, Z., Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  2700 Citations (Scopus)

• Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

  Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Z., Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  872 Citations (Scopus)

• Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

  Suchankova, G., Nelson, L. E., Gerhart-Hines, Z., Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review
  151 Citations (Scopus)
• 2008

  Metabolic adaptations through the PGC-1α and SIRT1 pathways

  Rodgers, J. T., Lerin, C., Gerhart-Hines, Z. & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access
  532 Citations (Scopus)