A hierarchical scheme for geodesic anatomical labeling of airway trees

Aasa Feragen, Jens Petersen, Megan Owen, Pechin Chien Pau Lo, Laura Thomsen, Mathilde M. W. Wille, Asger Dirksen, Marleen de Bruijne

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

24 Citations (Scopus)
2062 Downloads (Pure)

Abstract

We present a fast and robust supervised algorithm for label-
ing anatomical airway trees, based on geodesic distances in a geometric
tree-space. Possible branch label configurations for a given unlabeled air-
way tree are evaluated based on the distances to a training set of labeled
airway trees. In tree-space, the airway tree topology and geometry change
continuously, giving a natural way to automatically handle anatomical
differences and noise. The algorithm is made efficient using a hierarchical
approach, in which labels are assigned from the top down. We only use
features of the airway centerline tree, which is relatively unaffected by
pathology.

A thorough leave-one-patient-out evaluation of the algorithm is made on
40 segmented airway trees from 20 subjects labeled by 2 medical experts.
We evaluate accuracy, reproducibility and robustness in patients with
Chronic Obstructive Pulmonary Disease (COPD). Performance is statis-
tically similar to the inter- and intra-expert agreement, and we found no
significant correlation between COPD stage and labeling accuracy.
Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention – MICCAI 2012 : 15th International Conference, Nice, France, October 1-5, 2012, Proceedings, Part III
EditorsNicholas Ayache , Hervé Delingette , Polina Golland, Kensaku Mori
Number of pages9
PublisherSpringer
Publication date2012
Pages147-155
ISBN (Print)978-3-642-33453-5
ISBN (Electronic)978-3-642-33454-2
DOIs
Publication statusPublished - 2012
Event15th International Conference on Medical Image Computing and Computer-Assisted Intervention - Nice, France
Duration: 1 Oct 20125 Oct 2012
Conference number: 15

Conference

Conference15th International Conference on Medical Image Computing and Computer-Assisted Intervention
Number15
Country/TerritoryFrance
CityNice
Period01/10/201205/10/2012
SeriesLecture notes in computer science
Volume7512
ISSN0302-9743

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