A nation-wide twin study of social cognition in schizophrenia spectrum disorders

Cecilie K. Lemvigh*, Birte Y. Glenthoj, Birgitte Fagerlund

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)
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Abstract

We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ). All participants were recruited through the Danish registers. Patients showed several deficits in the ability to detect sarcasm. Impairments were also observed in the unaffected MZ co-twins, indicating that social cognitive deficits could be a genetic vulnerability indicator of the disease. Worse social cognition was associated with lower intelligence and higher levels of psychopathology in patients.

Original languageEnglish
Article number12
Journalnpj Schizophrenia
Volume8
Number of pages5
ISSN2334-265X
DOIs
Publication statusPublished - 2022

Keywords

  • DEFICITS
  • RELIABILITY
  • VALIDITY
  • SCALE

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