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A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study

  • B Risslegger
  • , T Zoran
  • , M Lackner
  • , M Aigner
  • , F Sánchez-Reus
  • , A Rezusta
  • , A Chowdhary
  • , S J Taj-Aldeen
  • , M C Arendrup
  • , S Oliveri
  • , D P Kontoyiannis
  • , A Alastruey-Izquierdo
  • , K Lagrou
  • , G Lo Cascio
  • , J F Meis
  • , W Buzina
  • , C Farina
  • , M Drogari-Apiranthitou
  • , A Grancini
  • , A M Tortorano
  • B Willinger, A Hamprecht, E Johnson, L Klingspor, V Arsic-Arsenijevic, O A Cornely, J Meletiadis, W Prammer, V Tullio, J-J Vehreschild, L Trovato, R E Lewis, E Segal, P-M Rath, P Hamal, M Rodriguez-Iglesias, E Roilides, S Arikan-Akdagli, A Chakrabarti, A L Colombo, M S Fernández, M T Martin-Gomez, H Badali, G Petrikkos, N Klimko, S M Heimann, J Houbraken, O Uzun, M Edlinger, S de la Fuente, C. Lass-Flörl

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections.

METHODS: A total of 370 cases from 21 countries were evaluated.

RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L).

CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.

Original languageEnglish
JournalClinical Microbiology and Infection
Volume23
Issue number10
Pages (from-to)776.e1-776.e5
ISSN1198-743X
DOIs
Publication statusPublished - 2017

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