A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial

Thomas Strøm; Torben Martinussen; Palle Toft

doi:10.1016/S0140-6736(09)62072-9

A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial

Thomas Strøm, Torben Martinussen, Palle Toft

Research output: Contribution to journal › Journal article › Research › peer-review

691 Citations (Scopus)

Abstract

Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation.

Original language	English
Journal	Lancet
Volume	375
Issue number	9713
Pages (from-to)	475-80
Number of pages	6
DOIs	https://doi.org/10.1016/S0140-6736(09)62072-9
Publication status	Published - 6 Feb 2010
Externally published	Yes

Access to Document

10.1016/S0140-6736(09)62072-9

Cite this

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title = "A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial",

abstract = "Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation.",

author = "Thomas Str{\o}m and Torben Martinussen and Palle Toft",

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AU - Strøm, Thomas

AU - Martinussen, Torben

AU - Toft, Palle

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Y1 - 2010/2/6

N2 - Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation.

AB - Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general intesive care unit of Odense University Hospital, Denmark, standard practice is a protocol of no sedation. We aimed to establish whether duration of mechanical ventilation could be reduced with a protocol of no sedation versus daily interruption of sedation.

U2 - 10.1016/S0140-6736(09)62072-9

DO - 10.1016/S0140-6736(09)62072-9

M3 - Journal article

C2 - 20116842

VL - 375

SP - 475

EP - 480

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9713

ER -