Abstract
The ileocolonic brake is impaired in short bowel syndrome (SBS) patients with distal bowel resections. An attenuated meal-stimulated hormone secretion may cause gastric hypersecretion, rapid gastric and intestinal transit and a poor adaptation. Attempting to restore this ileocolonic brake, this study evaluated the acute effects of continuous intravenous administration of glucagon-like peptide (GLP) 1 and 2, alone or in combination, on gastrointestinal function in SBS patients.
Original language | English |
---|---|
Journal | Regulatory Peptides |
Volume | 184 |
Issue number | 10 |
Pages (from-to) | 30-9 |
Number of pages | 10 |
ISSN | 0167-0115 |
DOIs | |
Publication status | Published - 10 Jun 2013 |