TY - JOUR
T1 - Aging and drug discovery
AU - Bakula, Daniela
AU - Aliper, Alexander M.
AU - Mamoshina, Polina
AU - Petr, Michael A.
AU - Teklu, Amanuel
AU - Baur, Joseph A.
AU - Campisi, Judith
AU - Ewald, Collin Y.
AU - Georgievskaya, Anastasia
AU - Gladyshev, Vadim N.
AU - Kovalchuk, Olga
AU - Lamming, Dudley W.
AU - Luijsterburg, Martijn S.
AU - Martín-Montalvo, Alejandro
AU - Maudsley, Stuart
AU - Mkrtchyan, Garik V.
AU - Moskalev, Alexey
AU - Jay Olshansky, S.
AU - Ozerov, Ivan V.
AU - Pickett, Alexander
AU - Ristow, Michael
AU - Zhavoronkov, Alex
AU - Scheibye-Knudsen, Morten
PY - 2018
Y1 - 2018
N2 - Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare.
AB - Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Here academia and industry came together, to discuss the latest progress and issues in aging research. The meeting covered talks about the mechanistic cause of aging, how longevity signatures may be highly conserved, emerging biomarkers of aging, possible interventions in the aging process and the use of artificial intelligence for aging research and drug discovery. Importantly, a consensus is emerging both in industry and academia, that molecules able to intervene in the aging process may contain the potential to transform both societies and healthcare.
KW - Aging
KW - Drug discovery
U2 - 10.18632/aging.101646
DO - 10.18632/aging.101646
M3 - Journal article
C2 - 30425188
AN - SCOPUS:85058128265
VL - 10
SP - 3079
EP - 3088
JO - Aging
JF - Aging
SN - 1945-4589
IS - 11
ER -