Abstract
Atrial fibrillation (AF) is common and is a prominent risk factor for ischemic stroke. Oral anticoagulant (OAC) therapy has been the main strategy for stroke prevention in AF patients; however, OAC therapy carries a bleeding risk and is not tolerated by all patients. Left atrial appendage (LAA) closure offers a non-pharmacological alternative for stroke prevention in patients with non-valvular AF. In this update, an overview of current and emerging LAA occluders is given - with special attention to the key design features of every single device and, if available, preclinical or clinical data.
Original language | English |
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Journal | Trends in Cardiovascular Medicine |
Volume | 29 |
Issue number | 4 |
Pages (from-to) | 228-236 |
ISSN | 1050-1738 |
DOIs | |
Publication status | Published - 2019 |
Keywords
- Animals
- Atrial Appendage/physiopathology
- Atrial Fibrillation/complications
- Cardiac Catheterization/adverse effects
- Equipment Design
- Humans
- Risk Factors
- Stroke/diagnosis
- Treatment Outcome