An overview of current and emerging devices for percutaneous left atrial appendage closure

Danny H F Chow, Yam-Hong Wong, Jai-Wun Park, Yat-Yin Lam, Tom De Potter, Josep Rodés-Cabau, Lluis Asmarats, Marcus Sandri, Eleftherios Sideris, Trevor McCaw, Randall J Lee, Horst Sievert, Lars Søndergaard, Ole De Backer

Research output: Contribution to journalReviewResearchpeer-review

18 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is common and is a prominent risk factor for ischemic stroke. Oral anticoagulant (OAC) therapy has been the main strategy for stroke prevention in AF patients; however, OAC therapy carries a bleeding risk and is not tolerated by all patients. Left atrial appendage (LAA) closure offers a non-pharmacological alternative for stroke prevention in patients with non-valvular AF. In this update, an overview of current and emerging LAA occluders is given - with special attention to the key design features of every single device and, if available, preclinical or clinical data.

Original languageEnglish
JournalTrends in Cardiovascular Medicine
Volume29
Issue number4
Pages (from-to)228-236
ISSN1050-1738
DOIs
Publication statusPublished - 2019

Keywords

  • Animals
  • Atrial Appendage/physiopathology
  • Atrial Fibrillation/complications
  • Cardiac Catheterization/adverse effects
  • Equipment Design
  • Humans
  • Risk Factors
  • Stroke/diagnosis
  • Treatment Outcome

Cite this