Analysis of two large functionally uncharacterized regions in the Methanopyrus kandleri AV19 genome

Lars Juhl Jensen; Marie Skovgaard; Thomas Sicheritz-Pontén; Merete Kjaer Jørgensen; Christiane Lundegaard; Corinna Cavan Pedersen; Nanna Petersen; David Ussery

Analysis of two large functionally uncharacterized regions in the Methanopyrus kandleri AV19 genome

Lars Juhl Jensen, Marie Skovgaard, Thomas Sicheritz-Pontén, Merete Kjaer Jørgensen, Christiane Lundegaard, Corinna Cavan Pedersen, Nanna Petersen, David Ussery

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

Abstract

For most sequenced prokaryotic genomes, about a third of the protein coding genes annotated are "orphan proteins", that is, they lack homology to known proteins. These hypothetical genes are typically short and randomly scattered throughout the genome. This trend is seen for most of the bacterial and archaeal genomes published to date.

Original language	English
Journal	B M C Genomics
Volume	4
Issue number	1
Pages (from-to)	12
ISSN	1471-2164
Publication status	Published - 2003
Externally published	Yes

Cite this

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title = "Analysis of two large functionally uncharacterized regions in the Methanopyrus kandleri AV19 genome",

abstract = "For most sequenced prokaryotic genomes, about a third of the protein coding genes annotated are {"}orphan proteins{"}, that is, they lack homology to known proteins. These hypothetical genes are typically short and randomly scattered throughout the genome. This trend is seen for most of the bacterial and archaeal genomes published to date.",

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T1 - Analysis of two large functionally uncharacterized regions in the Methanopyrus kandleri AV19 genome

AU - Jensen, Lars Juhl

AU - Skovgaard, Marie

AU - Sicheritz-Pontén, Thomas

AU - Jørgensen, Merete Kjaer

AU - Lundegaard, Christiane

AU - Pedersen, Corinna Cavan

AU - Petersen, Nanna

AU - Ussery, David

PY - 2003

Y1 - 2003

N2 - For most sequenced prokaryotic genomes, about a third of the protein coding genes annotated are "orphan proteins", that is, they lack homology to known proteins. These hypothetical genes are typically short and randomly scattered throughout the genome. This trend is seen for most of the bacterial and archaeal genomes published to date.

AB - For most sequenced prokaryotic genomes, about a third of the protein coding genes annotated are "orphan proteins", that is, they lack homology to known proteins. These hypothetical genes are typically short and randomly scattered throughout the genome. This trend is seen for most of the bacterial and archaeal genomes published to date.

M3 - Journal article

C2 - 12697059

SN - 1471-2164

VL - 4

SP - 12

JO - B M C Genomics

JF - B M C Genomics

IS - 1

ER -